| Sol-Y-Mar Court (Paignton) Limited | Households | 2005 |
| Sol-Y-Mar Management Ltd | Households | 2024 |
| Sola Leisure Ltd | Hospitality | 2026 |
| Solar PV & Electrical Ltd | Construction | 2022 |
| Soleiru Creative Ltd. | Wholesale & retail | 2020 |
| Solitzy Ltd | Wholesale & retail | 2018 |
| Solmag Ltd | Manufacturing | 2025 |
| Solviant Limited | Financial services | 2026 |
| Soma Shot Ltd | Manufacturing | 2026 |
| Somers Court Bell View Management Company Limited | Households | 2020 |
| Somers Lodge Property Management Ltd | Households | 2024 |
| Sonder Arts Collective Community Interest Company | Education | 2025 |
| SOS Store Ltd | Transport & logistics | 2022 |
| SOS SW Limited | Transport & logistics | 2019 |
| Sound Communities Community Interest Company | Information & communication | 2012 |
| Source & Stone Group Ltd | Construction | 2025 |
| South CE Ltd | Health & social care | 2022 |
| South Coast Hospitality Group Ltd | Professional & scientific | 2025 |
| South Devon Accounting and Business Services Limited | Professional & scientific | 2009 |
| South Devon Fhah Ltd | Professional & scientific | 2019 |
| South Hams Express Limited | Transport & logistics | 2016 |
| South Legacy Limited | Hospitality | 2013 |
| South West Asset Finance Limited | Financial services | 2009 |
| South West Balustrades Limited | Construction | 2021 |
| South West Building Controls Ltd | Construction | 2024 |
| South West Explorer Ltd | Information & communication | 2026 |
| South West Leak Detection Limited | Other services | 2019 |
| South West Paraplanning Ltd | Financial services | 2024 |
| South West Procurement Limited | Wholesale & retail | 2013 |
| South West RIB Rides (Torbay) Ltd | Extraterritorial | 2020 |
| South West Services Limited | Manufacturing | 1984 |
| South West Steel Reinforcements Ltd | Administrative & support | 2019 |
| South West Taverns Ltd | Hospitality | 2023 |
| South West Vending Limited | Hospitality | 2021 |
| South Western Carpet Distributors (Torbay) Limited | Wholesale & retail | 1968 |
| Southern Strands Hair Co. Ltd | Other services | 2025 |
| Southsands Management Company Limited | Households | 2001 |
| Specialised Surfacing Limited | Construction | 2016 |
| Speed Culture Limited | Wholesale & retail | 1991 |
| Spencer Holdings Limited | Professional & scientific | 2011 |
| Spindatrecord Ltd | Wholesale & retail | 2024 |
| Spiral Carpets Limited | Construction | 2019 |
| Spot on Home Improvements Ltd | Administrative & support | 2023 |
| SPS Fit Ltd | Arts & recreation | 2025 |
| Srinivas and SON Ltd | Health & social care | 2013 |
| ST John the Baptist Trading Co Limited | Wholesale & retail | 2006 |
| ST. Peter's Development Torbay Limited | Construction | 1994 |
| Staffing 4 Everything Limited | Professional & scientific | 2025 |
| Stallion Investments Limited | Construction | 2002 |
| Standerwick Land Design Ltd | Professional & scientific | 2024 |
| Star Draws & Comps Ltd | Arts & recreation | 2023 |
| Starfyre Games Ltd | Information & communication | 2025 |
| Stella Isaac Illustration Ltd | Arts & recreation | 2023 |
| Stellar Films Limited | Information & communication | 2004 |
| Stenner Holdings Ltd | Real estate | 2025 |
| Stephie & Stefna Trading (PVT) Ltd | Wholesale & retail | 2025 |
| Steve Terry Building Services Ltd | Construction | 2020 |
| Stewart Cockburn Ltd | Information & communication | 2019 |
| Stockbox Events Ltd | Hospitality | 2025 |
| Stones Throw Brixham Ltd | Hospitality | 2026 |
| Stoneworx.Sw Ltd | Real estate | 2015 |
| Story Sense Ltd | Education | 2022 |
| Strata Developments Ltd | Real estate | 2025 |
| Strongholduk Ltd | Construction | 2014 |
| Studio Yarner Ltd | Professional & scientific | 2024 |
| Style App Limited | Wholesale & retail | 2025 |
| Sulaco Property SW Ltd | Real estate | 2020 |
| Summit Scaffolding SW Ltd | Construction | 2024 |
| Sunmez Food UK Ltd | Hospitality | 2024 |
| Sunrider Drones Limited | Professional & scientific | 2018 |
| Sunshine Developments (SW) Ltd | Construction | 2021 |
| Supa-Shade Blinds and Awnings Ltd | Manufacturing | 2003 |
| Supa-Shade Engineering Ltd | Manufacturing | 2023 |
| Superb Holdings Limited | Financial services | 2020 |
| Superhub Ltd | Administrative & support | 2020 |
| Superhub Media Ltd | Other services | 2019 |
| Supernova UK Limited | Professional & scientific | 2001 |
| Supervideo Ltd | Wholesale & retail | 2020 |
| Support Services Southwest Limited | Energy | 2004 |
| Swan Property Lets Ltd | Real estate | 2025 |
| Sway Hair Extensions Trade Limited | Wholesale & retail | 2017 |
| Swethuk Limited | Households | 2026 |
| Swift Carpets and Flooring Ltd | Wholesale & retail | 2010 |
| Swift Logistics (SW) Ltd | Transport & logistics | 2023 |
| Sylvan Property Management Ltd | Real estate | 2002 |
| Szabo Smith UK Ltd | Wholesale & retail | 2023 |
| T J Reynolds Electrical Contractors Ltd | Construction | 2019 |
| T-Me Clothing Limited | Wholesale & retail | 2016 |
| TA & RWP Enterprises Limited | Information & communication | 2026 |
| Tabs Accountants Ltd | Professional & scientific | 2002 |
| Taco Media Ltd | Information & communication | 2026 |
| Taher Limited | Administrative & support | 2001 |
| Tailored Torbay Limited | Other services | 2025 |
| TAK International Ltd | Transport & logistics | 2023 |
| Taleblazers CIC | Education | 2021 |
| Talentcoast Ltd | Administrative & support | 2026 |
| Tam's Events and Catering Ltd | Hospitality | 2024 |
| Tambu Outdoor UK Ltd | Wholesale & retail | 2021 |
| Tangerine Plant Limited | Construction | 2015 |
| Tango Feast Ltd | Arts & recreation | 2025 |