| Dubwood Tuning & Camper Conversions Ltd | Professional & scientific | 2026 |
| Duchesperfectfinds Ltd | Wholesale & retail | 2026 |
| Ducky Drones Ltd | Manufacturing | 2025 |
| Ducky Zebra Ltd | Wholesale & retail | 2019 |
| Dudo Creative Ltd. | Information & communication | 2020 |
| Duerer Press Limited | Arts & recreation | 2014 |
| Duhok News Oxford Ltd | Wholesale & retail | 2022 |
| Duke Property Ltd | Hospitality | 2023 |
| Dukes Wharf Management Company Limited | Households | 2000 |
| Dungey Construction Limited | Construction | 2012 |
| Dunne Property Developments Limited | Construction | 2015 |
| Dunstall Brand Marketing Limited | Professional & scientific | 2014 |
| Dunwell (Oxford) Limited | Health & social care | 2010 |
| Duologee Ltd | Professional & scientific | 2025 |
| Duval Betgate Ltd | Construction | 2009 |
| Duval Inns Ltd | Hospitality | 2021 |
| DV Vinyl Limited | Information & communication | 2016 |
| Dwell Housing Ltd | Real estate | 2019 |
| Dwell Oxford | Construction | 2020 |
| DWG Plans Cotswolds Ltd | Professional & scientific | 2024 |
| Dylogic Management Services Ltd | Information & communication | 2019 |
| Dynamic Aesthetics Ltd | Wholesale & retail | 2024 |
| Dynamic Culture Ltd | Wholesale & retail | 2013 |
| Dynamic Engineering Simulation Ltd | Professional & scientific | 2013 |
| Dynamic Propulsion Limited | Wholesale & retail | 2026 |
| Dynamic Solutions Incorporation Ltd | Information & communication | 2007 |
| Dynamic Thermal Systems Ltd | Professional & scientific | 2022 |
| Dynamique Limited | Professional & scientific | 1997 |
| Dynaverse Ltd | Information & communication | 2003 |
| Dynix Simulations Ltd | Professional & scientific | 2026 |
| DYS 44 Art Gallery Limited | Administrative & support | 2015 |
| E Enterprises Ltd | Real estate | 2018 |
| E H & S Consultancy Limited | Professional & scientific | 2023 |
| E Healthcare Limited | Health & social care | 2015 |
| E&J Property Group Ltd | Real estate | 2026 |
| E&T ALL Purpose Ltd | Construction | 2023 |
| E-Group Property Limited | Professional & scientific | 2021 |
| E-Livery Ltd | Transport & logistics | 2020 |
| E. Galilee Consultancy Limited | Professional & scientific | 1997 |
| E.Dumani Construction Ltd | Administrative & support | 2017 |
| E.F Kerin & Sons Ltd | Administrative & support | 2012 |
| E.K. Mobile Entertainment Limited | Arts & recreation | 2015 |
| E.L.R Engineering Ltd | Construction | 2026 |
| E.N.K. Construction Limited | Construction | 2018 |
| E.W. Manners & SON Limited | | 1970 |
| E360 Consulting Ltd | Professional & scientific | 2026 |
| E8PORTAL Ltd | Information & communication | 2009 |
| Eafor Limited | Real estate | 2017 |
| Eagle Electrical and Property Services Limited | Construction | 2025 |
| Eagle Taxi Ltd | Transport & logistics | 2022 |
| Eagles Construction and Service Limited | Construction | 2021 |
| Eaglespan Limited | Wholesale & retail | 1986 |
| Eagleswood Ltd | Transport & logistics | 2026 |
| Eaglow PVT Ltd | Information & communication | 2026 |
| Eala Consulting Limited | Professional & scientific | 2023 |
| Eamaw Ltd | Wholesale & retail | 2025 |
| Eames Events Limited | Extraterritorial | 2010 |
| Eamonn Rose Properties Limited | Real estate | 2025 |
| Earls Green Management Company Limited | Real estate | 2021 |
| Earnest Tutors Ltd | Education | 2017 |
| Earnestereo Ltd | Manufacturing | 2024 |
| Earnestfilm Ltd | Information & communication | 2013 |
| Earnestory Ltd | Information & communication | 2020 |
| Earnestudios Ltd | Information & communication | 2020 |
| Earth and Pearl Ltd | Manufacturing | 2025 |
| Earth Hazards International Ltd | Professional & scientific | 2025 |
| Earth Safe Products Ltd | Manufacturing | 2010 |
| EAS Labels Direct Limited | Wholesale & retail | 2009 |
| East END Enterprises Limited | Hospitality | 2014 |
| East Stour Management Company Limited | Households | 2005 |
| East Street Studio Oxford Limited | Health & social care | 2019 |
| East Timor Logistics Solutions Limited | Transport & logistics | 2025 |
| Eastern Continental Store Ltd | Wholesale & retail | 2011 |
| Eastern Trade Ltd | Wholesale & retail | 2021 |
| Eastwood-Morrells Limited | Wholesale & retail | 2020 |
| Easy Linen Supplier Limited | Administrative & support | 2025 |
| Easyown Limited | Wholesale & retail | 2026 |
| EAT Pizza Oxon Ltd | Hospitality | 2025 |
| EBA Conferences Limited | Administrative & support | 2012 |
| EBB Publishing Limited | Information & communication | 2021 |
| EBD Group Limited | Financial services | 2022 |
| Ebonite Management Limited | Administrative & support | 2012 |
| Ebudget Ltd | Information & communication | 2023 |
| Ebury Group Holdings Limited | Financial services | 1991 |
| EC Catering Partners Limited | Hospitality | 2024 |
| Echo Healthcare Ltd | Education | 2022 |
| Echolalic Limited | Information & communication | 2026 |
| Eclipse AI Consulting Ltd | Information & communication | 2024 |
| Eclm Economics Limited | Professional & scientific | 2013 |
| Eco Autos Ltd | Wholesale & retail | 2024 |
| Eco Systems GLO Ltd | Administrative & support | 2025 |
| Eco-Fridge UK Limited | Administrative & support | 2009 |
| Ecofit Construction Ltd | Construction | 2012 |
| Ecoheat Innovation Ltd | Construction | 2025 |
| Ecole DE Lumiere Ltd | Education | 2026 |
| Ecological Cleaning Services Ltd | Administrative & support | 2020 |
| Ecology by Design Limited | Professional & scientific | 2014 |
| Ecommerce Partners Limited | Wholesale & retail | 2023 |
| Economy Consulting Ltd | Financial services | 2018 |
| Ecoplastex Ltd | Manufacturing | 2023 |