| Environmental Consulting Engineers Limited | Professional & scientific | 2011 |
| EPA Property Ltd | Real estate | 2022 |
| Equity Staffing Limited | Administrative & support | 2017 |
| ER Travel Overseas Ltd | Professional & scientific | 2020 |
| Erha Aamir Collective Ltd | Wholesale & retail | 2025 |
| Ermine Security Limited | Administrative & support | 2014 |
| ES Civils Limited | Construction | 2022 |
| Essential GAS Ltd | Construction | 2019 |
| Essential Legal Limited | Professional & scientific | 2021 |
| Essentially Together Ltd | Financial services | 2024 |
| Estera WAX and Wellness Ltd | Wholesale & retail | 2025 |
| Ethelaustin.Co.Uk Limited | Wholesale & retail | 2017 |
| Ets-Solutions NW Ltd | Administrative & support | 2016 |
| Eurofood Partners Ltd | Wholesale & retail | 2004 |
| European Doorsets & Ironmongery Limited | Extraterritorial | 2006 |
| European Doorsets Limited | Extraterritorial | 2006 |
| European Horseboxes Limited | Wholesale & retail | 2016 |
| European Trading Limited | Other services | 2018 |
| European Wood Products Limited | Manufacturing | 1990 |
| Evaristo Estates Ltd | Households | 2018 |
| Evelyn House Care Ltd | Health & social care | 2025 |
| Everitt Limited | Mining & quarrying | 2005 |
| Evermac Limited | Construction | 2017 |
| Everything Ultrasound Limited | Health & social care | 2025 |
| Evidentia Consulting Limited | Professional & scientific | 2025 |
| EW & KM Webster Ltd | Agriculture & fishing | 2014 |
| EWC Environmental Services Ltd | Water & waste | 2018 |
| Exceptional Care Developments Limited | Real estate | 2017 |
| Exceptional Care Limited | Health & social care | 2013 |
| Exchange Financial Services Limited | Financial services | 1988 |
| Exec Travel NW Ltd | Transport & logistics | 2021 |
| Exit Hardware Limited | Manufacturing | 2017 |
| Explayers Ltd | Other services | 2022 |
| Explorer Boats (UK) Ltd | Transport & logistics | 2015 |
| F & H Construction (NW) Ltd | Construction | 2023 |
| F P Baybutt Limited | Agriculture & fishing | 2018 |
| F Thomas Limited | Hospitality | 2012 |
| Face Salon Ltd | Other services | 2022 |
| Facilitate Expert Solutions Limited | Administrative & support | 2016 |
| Fadel Medical Ltd | Health & social care | 2026 |
| Fairbeck Limited | Construction | 2021 |
| Fairhoward Contracting Ltd | Other services | 2019 |
| Fairways Consulting Services Limited | Professional & scientific | 2021 |
| Falcon Nest Limited | Administrative & support | 2025 |
| Falcon Place Limited | Real estate | 2012 |
| Family Psychology Services Limited | Health & social care | 2013 |
| Famous Brand Wholesale Ltd | Wholesale & retail | 2014 |
| Farrier Drinks Ltd | Hospitality | 2023 |
| Fast Track Repairs (NW) Ltd | Construction | 2009 |
| Fauve Limited | Administrative & support | 2011 |
| Fenben Productions Limited | Information & communication | 2009 |
| Fenestration Consulting Solutions Limited | Professional & scientific | 2003 |
| Festivalz Ltd | Hospitality | 2025 |
| Fettler Drinks Ltd | Hospitality | 2023 |
| Ffmbvelocafe Limited | Hospitality | 2015 |
| FIC Developments Limited | Construction | 2020 |
| Fieldsongs Limited | Information & communication | 2016 |
| Financial Services (Sefton) Limited | Financial services | 1985 |
| Finch Electrical Contractors Limited | Construction | 2025 |
| Firefly Agency Limited | Professional & scientific | 2015 |
| First Class (Tyldesley) Limited | Wholesale & retail | 2020 |
| First Class Accommodation Limited | Real estate | 2025 |
| First Class Accountants Ltd | Professional & scientific | 2012 |
| First Foot Forward Sports Management Ltd | Professional & scientific | 2024 |
| Firwood Properties (North West) Limited | Construction | 1986 |
| Fitness Flow Pilates Limited | Other services | 2017 |
| Fitzgeralds Vehicles Limited | Manufacturing | 2019 |
| Five 0 Taxis Blueline Ormskirk Ltd | Transport & logistics | 2019 |
| Five Elements Gracie Jiu-Jitsu Limited | Education | 2022 |
| Flagship Automation Limited | Information & communication | 2020 |
| Flair Property Co. Limited | Real estate | 2003 |
| Fleet Control Services Ltd | Administrative & support | 2019 |
| Fleetwood Rentals Limited | Administrative & support | 2025 |
| Flinders Chase Limited | Construction | 2012 |
| Flinders Properties LLP | | 2019 |
| Florida Holdings Limited | Financial services | 2025 |
| Flourish Research Ltd | Professional & scientific | 2018 |
| Flow Payroll Ltd | Professional & scientific | 2025 |
| Fluff and Flock Rescue CIC | Agriculture & fishing | 2024 |
| FLY Llanbedr Limited | Transport & logistics | 2014 |
| FM Consultants UK Ltd | Construction | 2021 |
| Focus Critical Limited | Information & communication | 2014 |
| Foggs Properties Ltd | Real estate | 2024 |
| Foot Faults Podiatry Limited | Health & social care | 2021 |
| Format Golfing Ltd | Manufacturing | 2026 |
| Fortress Scaffolding (NW) Limited | Construction | 2016 |
| Forum Industries Ltd | Wholesale & retail | 2000 |
| Foster Medical Ltd | Health & social care | 2016 |
| Foulkes Associates Ltd | Professional & scientific | 2011 |
| Four Seasons Garden Services (NW) Ltd | Administrative & support | 2026 |
| Foxglove & Fern Limited | Wholesale & retail | 2026 |
| FOY Properties Ltd | Households | 2020 |
| Frampton Electrical Solutions Ltd | Construction | 2020 |
| Frampton Group Ltd | Financial services | 2023 |
| Frampton Solar Ltd | Construction | 2023 |
| Francis Michael Beckett Ltd | Construction | 2024 |
| Francographics Ltd | Professional & scientific | 2013 |
| Fraser O'Hare Limited | Professional & scientific | 2007 |
| Freddies OM Ltd | Wholesale & retail | 2025 |
| Freeflow NW Ltd | Administrative & support | 2016 |