| CSC Couriers Ltd | Transport & logistics | 2026 |
| CSC Home Improvements Ltd | Construction | 2019 |
| Culshaw Ltd | Manufacturing | 2015 |
| Cult Football Limited | Wholesale & retail | 2020 |
| Culture Calendar Limited | Arts & recreation | 2022 |
| Cunliffe Estates Ltd | Real estate | 2018 |
| CUO Property's Ltd | Real estate | 2025 |
| Cura Connections Ltd | Households | 2025 |
| Currency Matters Retail Limited | Financial services | 2013 |
| Current Concepts Ltd | Construction | 2017 |
| CW Engineering Services Ltd | Professional & scientific | 2023 |
| CWJ Properties and Investments Limited | Real estate | 2022 |
| CWR Investments Ltd | Real estate | 2018 |
| CXH Enterprise Ltd | Wholesale & retail | 2025 |
| Cygnet Design Limited | Wholesale & retail | 2017 |
| Cypress House Liverpool Limited | Administrative & support | 2013 |
| D & E Monk Limited | Wholesale & retail | 2015 |
| D E Corlett Accountancy Ltd | Professional & scientific | 2011 |
| D E Strype Limited | Other services | 2026 |
| D J & J Wignall Limited | Construction | 2013 |
| D L Social Work Ltd | Health & social care | 2021 |
| D.C. Scott & Sons (Ormskirk) Limited | Other services | 1979 |
| D.H.W. Agencies Limited | Wholesale & retail | 2003 |
| D.J.B. & K. Anderson Ltd | Transport & logistics | 2012 |
| D.J.R Homes Limited | Real estate | 2026 |
| D.Lomas and Sons Ltd | Transport & logistics | 2018 |
| D.Ryan Construction Ltd | Construction | 2016 |
| Dabrenco Limited | Health & social care | 2024 |
| Daco Property Limited | Real estate | 2025 |
| Daforza (Distribution) Ltd | Wholesale & retail | 2017 |
| Daga Holdings Ltd | Financial services | 2025 |
| Daily Dose Coffee Ltd | Hospitality | 2020 |
| Dakota BP Management Company Ltd | Real estate | 2019 |
| Dalajabe Global Ltd | Extraterritorial | 2006 |
| DAN Heavican Personal Training Limited | Arts & recreation | 2016 |
| Dann Enterprises Limited | Financial services | 2025 |
| DAR Industrial Trucks Limited | Manufacturing | 2021 |
| Darcie Property Limited | Hospitality | 2023 |
| Darren Mcilwaine Property Limited | Construction | 2018 |
| Darren's Fresh Fish Ltd | Wholesale & retail | 2013 |
| Dave Craven Ltd | Information & communication | 2017 |
| Davenport Transport Limited | Transport & logistics | 2001 |
| David a LEA & Sons Ltd | Hospitality | 2010 |
| Dayz Waste Solutions Ltd | Water & waste | 2021 |
| DCP Trading Ltd | Wholesale & retail | 2025 |
| DDT (UK) Ltd | Construction | 2008 |
| Deanswood Trading Limited | Other services | 2019 |
| Dearg Obartuin Ltd | Information & communication | 2018 |
| Dears Brack Limited | Real estate | 2004 |
| Debtlaw Collections Ltd | Administrative & support | 2020 |
| Decades Consulting Ltd | Professional & scientific | 2025 |
| Decorators for Christmas Ltd | Administrative & support | 2023 |
| Deelex Construction Ltd | Administrative & support | 2014 |
| Degreemain Limited | Manufacturing | 1994 |
| Deli-Licious Ormskirk Ltd | Hospitality | 2018 |
| Dell House Limited | Real estate | 2006 |
| Dell House Summerhill Management Company Limited | Real estate | 2006 |
| Delta Fourtwo Project Planning Ltd | Professional & scientific | 2017 |
| Deltagap Limited | Extraterritorial | 2020 |
| Derv Developments Ltd | Professional & scientific | 2023 |
| DF Landscapes Ltd | Administrative & support | 2016 |
| DGR Building Maintenance Limited | Construction | 2010 |
| DHM Fork Trucks Ltd | Manufacturing | 2017 |
| DI Ceramica Ltd | Construction | 2010 |
| Diamond Edge Limited | Wholesale & retail | 1972 |
| Diamond Rigging UK Ltd | Information & communication | 2025 |
| Diamondjetwash Limited | Other services | 2025 |
| Diane Frances Limited | Other services | 2019 |
| Dianna Ltd | Other services | 2017 |
| Diaspora Direct Ltd | Other services | 2025 |
| Dickinson Parker Hill Solicitors Limited | Professional & scientific | 2023 |
| Digital Accountancy Limited | Professional & scientific | 2013 |
| Digital Community Solutions CIC | Information & communication | 2017 |
| Digital Firestarter Ltd | Professional & scientific | 2018 |
| Digital Perspective Limited | Information & communication | 2020 |
| Dinas Bay Management Company Limited | Professional & scientific | 1990 |
| Dingle Heyes Farm Stud and Equestrian Limited | Agriculture & fishing | 2016 |
| Direct 4 Baby Limited | Wholesale & retail | 2012 |
| Direct Accident Management Limited | Administrative & support | 1996 |
| Direct Technology Communities CIC | Information & communication | 2017 |
| Directfleet Group Ltd | Wholesale & retail | 2020 |
| Dirt B Gone Cleaning Ltd | Administrative & support | 2019 |
| Discovery European Ltd | Administrative & support | 2021 |
| Distant Journeys DMC Limited | Hospitality | 2021 |
| Distant Journeys Limited | Administrative & support | 2014 |
| Distinctive Plastics Ltd | Construction | 2005 |
| DJS Consultancy Group Ltd | Households | 2024 |
| DJW Ainscough Ltd | Construction | 2026 |
| DK Dance Ltd | Arts & recreation | 2021 |
| DL LAB Consultants Ltd | Professional & scientific | 2024 |
| DM Engineering (NW) Limited | Professional & scientific | 2020 |
| DM Professional Services Ltd | Information & communication | 2020 |
| DM Webstuff Ltd | Administrative & support | 2018 |
| DMC Creative Services Limited | Information & communication | 2025 |
| DMC Offshore Service Limited | Professional & scientific | 2022 |
| DMG Distribution Ltd | Administrative & support | 2019 |
| DMW Properties Ltd | Real estate | 2020 |
| DN Leads Ltd | Professional & scientific | 2025 |
| Dobsons Produce Holdings Ltd | Financial services | 2014 |
| Dolce Ainsdale Restaurants Ltd | Hospitality | 2026 |