| Studio Clark Ltd | Professional & scientific | 2021 |
| Styling Touch Ltd | Construction | 2020 |
| Stylish Blinds Ltd | Manufacturing | 2025 |
| Subc Engineering Limited | Administrative & support | 2010 |
| Subc Training Limited | Professional & scientific | 2011 |
| Subsea Insight Ltd | Manufacturing | 2021 |
| Succeed Global Ltd | Information & communication | 2025 |
| Succeed Impact C.I.C. | Other services | 2025 |
| Suetek Ltd | Wholesale & retail | 2025 |
| Sukr Limited | Administrative & support | 2009 |
| Summerwood Holdings Limited | Financial services | 2023 |
| Summerwood Ltd | Households | 2019 |
| Superbru Ltd | Wholesale & retail | 2023 |
| Superior Developments Limited | Real estate | 1998 |
| Survey 1ST Professionals Limited | Construction | 2026 |
| Survey 1ST UK Ltd | Construction | 2022 |
| Survey Accessories Limited | Wholesale & retail | 2024 |
| Suttons Garage Limited | Wholesale & retail | 2025 |
| Svante Studio UK Limited | Wholesale & retail | 2024 |
| SW Glazing Group Limited | Manufacturing | 2022 |
| Swan Mechanical (Services) Ltd | Construction | 2012 |
| Swifts Recovery & MOT Limited | Wholesale & retail | 2022 |
| Swiftstep Limited | Professional & scientific | 1998 |
| SY Management Limited | Professional & scientific | 2025 |
| Sycamore Dog Field Limited | Arts & recreation | 2019 |
| Sycamore Equestrian Limited | Other services | 2017 |
| T. Silcock and Sons Limited | Extraterritorial | 2015 |
| T.E. Smith Ltd | Agriculture & fishing | 2020 |
| Tailored Climate Solutions Ltd | Construction | 2022 |
| Tails and Trails Dog Walker Ltd | Other services | 2020 |
| Take a Peek Limited | Health & social care | 2006 |
| Talk Change Grow UK CIC | Education | 2021 |
| Tandm BID Ltd | Information & communication | 2024 |
| TAO Services Ltd | Other services | 2024 |
| TAP Room Twelve Ltd | Hospitality | 2022 |
| TAP28 Limited | Wholesale & retail | 2026 |
| Tapas R US Limited | Hospitality | 2012 |
| Target Controls PK North West Ltd | Professional & scientific | 2017 |
| Tastebuds (Lancashire) Limited | Hospitality | 2014 |
| Tatlocks Grange Management Company Limited | Administrative & support | 2010 |
| Tattersall Family Limited | Financial services | 2024 |
| Taurus Groundworks Ltd | Construction | 2020 |
| Taylor's Bar Ltd | Hospitality | 2015 |
| Taylors Farm Shop Limited | Agriculture & fishing | 2008 |
| TBH Electrical Limited | Construction | 2023 |
| Tbls Textiles Limited | Wholesale & retail | 2018 |
| TBR Property Ltd. | Real estate | 2000 |
| Tcnc Investments Ltd | Real estate | 2023 |
| TCS071428Y Ltd | Professional & scientific | 2024 |
| TDI Financial Intermediary Solutions Limited | Financial services | 2025 |
| Team Aprilia Limited | Arts & recreation | 1996 |
| Team DMO Ltd | Professional & scientific | 2018 |
| Team Go Green Ltd | Arts & recreation | 2015 |
| Team Lovely Limited | Hospitality | 2024 |
| Techsalv Limited | Other services | 2024 |
| Tedham Construction NW Ltd | Construction | 2025 |
| Teesside Steel Company Limited | Manufacturing | 2025 |
| Teesside Steel Corporation Limited | Manufacturing | 2025 |
| Tempest Tempest Ltd | Transport & logistics | 2024 |
| Tenderfoot Theatre C.I.C. | Arts & recreation | 2021 |
| Tennis 360 Limited | Administrative & support | 2018 |
| Test Electrical & Mechanical Services Ltd | Construction | 2024 |
| TF Joinery & Building Contractors Ltd | Construction | 2026 |
| TFP Consultants Limited | Professional & scientific | 2018 |
| TG Techno Limited | Extraterritorial | 2014 |
| TG Trade Holdings Limited | Financial services | 2019 |
| TGM Electrical and Network Solutions Limited | Construction | 2014 |
| Thanks for Dinner Ltd | Arts & recreation | 2023 |
| THE 1:1 Diet by Cambridge Weight Plan With Gill Ltd | Health & social care | 2023 |
| THE Aesthetic Clinic (NW) Ltd | Other services | 2015 |
| THE Aesthetics and Health Company Ltd | Other services | 2016 |
| THE Air Conditioning Network Limited | Professional & scientific | 2024 |
| THE Andrews Family Property Company Limited | Real estate | 2014 |
| THE Ashcroft Group Holdings Limited | Financial services | 2026 |
| THE Atacc Group Ltd | Administrative & support | 2011 |
| THE Aviary Ormskirk Limited | Hospitality | 2021 |
| THE Bagel Deli Ltd | Wholesale & retail | 2018 |
| THE Bakehouse Formby C.I.C. | Hospitality | 2021 |
| THE Bicycle Lounge Limited | Wholesale & retail | 2011 |
| THE Boathouse Rufford Limited | Hospitality | 2014 |
| THE Boot Room Bar Ltd | Hospitality | 2026 |
| THE Bridal Barn Boutique Limited | Wholesale & retail | 2016 |
| THE BUS Bar Ltd | Hospitality | 2024 |
| THE Cake Pavilion Limited | Hospitality | 2017 |
| THE Calm Charm Ltd | Manufacturing | 2020 |
| THE Clarke Family Charitable Foundation | Health & social care | 2018 |
| THE Collectors Circuit Ltd | Administrative & support | 2026 |
| THE Construction Company North Limited | Real estate | 2016 |
| THE Costs Room Limited | Professional & scientific | 2016 |
| THE Costs Room Medical Limited | Professional & scientific | 2024 |
| THE Cosy POD Company Ltd | Administrative & support | 2022 |
| THE Cricketers (Ormskirk) Ltd | Hospitality | 2013 |
| THE Crowes Nest Cafe Ltd | Hospitality | 2025 |
| THE Digital Media Guys Ltd | Information & communication | 2024 |
| THE Dogs Dangleez Limited | Wholesale & retail | 2020 |
| THE Duck Inn (Ormskirk) Limited | Hospitality | 2025 |
| THE Edge Lets Limited | Real estate | 2013 |
| THE Farm Burscough Limited | Wholesale & retail | 2013 |
| THE Festival Manager Ltd | Hospitality | 2020 |
| THE Flower Farm Lancashire Limited | Agriculture & fishing | 2016 |