| Dusk Till Dawn Sleepovers Ltd | Other services | 2019 |
| DVS Healthcare Ltd | Extraterritorial | 2008 |
| DW Fabrications Limited | Construction | 2021 |
| DW Financial Services Ltd | Extraterritorial | 2015 |
| DW Frostbite Ltd | Professional & scientific | 2025 |
| DWA Law Ltd | Professional & scientific | 2025 |
| Dwellin Limited | Real estate | 2025 |
| DWF Civils Limited | Construction | 2026 |
| Dylbev Ltd | Professional & scientific | 2024 |
| Dyllis Properties Limited | Real estate | 2018 |
| Dynaavs Ltd | Manufacturing | 2024 |
| Dynamic Carer Manchester Limited | Extraterritorial | 2023 |
| Dynamic Cleaning Empire Ltd | Administrative & support | 2024 |
| Dynamic Controls Limited | Manufacturing | 1982 |
| Dynamic Massage Ltd | Other services | 2016 |
| Dynamic Measures Ltd | Administrative & support | 2020 |
| Dynamic Solutions (MCR) Limited | Manufacturing | 2021 |
| Dynamic Spray Ltd | Other services | 2019 |
| Dynamic UK Solutions Limited | Administrative & support | 2021 |
| Dynamicsbase Limited | Administrative & support | 2008 |
| E & S Prosthetics Ltd | Health & social care | 2002 |
| E - Gauge Products Limited | Professional & scientific | 2007 |
| E a Ceramics Limited | Wholesale & retail | 2014 |
| E and a Developments Limited | Real estate | 2011 |
| E and S Collectables Ltd | Wholesale & retail | 2012 |
| E Davies Properties Ltd | Real estate | 2026 |
| E Inspiring Ltd | Wholesale & retail | 2023 |
| E Knowles Ltd | Professional & scientific | 2013 |
| E L Rubber Company Ltd | Manufacturing | 2017 |
| E L Wilkinson Limited | Professional & scientific | 2026 |
| E R Legal Limited | Professional & scientific | 2026 |
| E Smoke News Ltd | Wholesale & retail | 2021 |
| E-Basket Ltd | Wholesale & retail | 2020 |
| E-Ciggers Ltd | Wholesale & retail | 2018 |
| E-Marketplaces Service Ltd | Wholesale & retail | 2024 |
| E-Solutionzzz Limited | Wholesale & retail | 2024 |
| E. Edwards Consulting Limited | Professional & scientific | 2025 |
| E.A.E. Polishing Services Company Limited | Manufacturing | 1981 |
| E.C. Creative Services Limited | Transport & logistics | 1993 |
| E.C.C.I. Ltd | Administrative & support | 2011 |
| E.E.L. Property Maintenance Coordination Ltd | Construction | 2020 |
| E.H.A. Foods Ltd | Hospitality | 2016 |
| E.T.I.P. Company Ltd | Professional & scientific | 2016 |
| E.Z. Bakery Ltd | Manufacturing | 2025 |
| Eaba Express Ltd | Administrative & support | 2017 |
| Eagle I Care Ltd | Health & social care | 2024 |
| Eagle I Imports Ltd | Wholesale & retail | 2023 |
| Eagle Management & Asset Trading Ltd | Construction | 2020 |
| Eagle Property Rentals Ltd | Real estate | 2023 |
| Eagle Traders Manchester Limited | Wholesale & retail | 2023 |
| Earlscrest Limited | Hospitality | 2021 |
| Early Life Childminding Ltd | Health & social care | 2021 |
| Early Years Development Co Ltd | Health & social care | 2021 |
| Earlymatch Limited | Manufacturing | 1990 |
| Earn in Property Ltd | Real estate | 2017 |
| Earnovia AI Limited | Wholesale & retail | 2025 |
| Earth Cures Ltd | Wholesale & retail | 2023 |
| Earthbeam Limited | Wholesale & retail | 2025 |
| Earthcast Services Limited | Manufacturing | 1993 |
| East Lancashire Mark Benevolent Fund Limited | Health & social care | 1966 |
| East Manchester DAB Limited | Information & communication | 2021 |
| East to West (Disley) Ltd | Hospitality | 2021 |
| Eastern Catering Services Oldham Ltd | Administrative & support | 2019 |
| Eastern Chai Ltd | Hospitality | 2021 |
| Eastern Concept Limited | Real estate | 2007 |
| Eastern Halal Poultry Ltd | Manufacturing | 2023 |
| Eastern Pavilion Oldham Limited | Hospitality | 2017 |
| Eastlands Supplies Ltd. | Wholesale & retail | 2008 |
| Eastline Electrical Solutions Limited | Construction | 2022 |
| Eastline Estates Ltd | Real estate | 2025 |
| Easy Caring Ltd | Health & social care | 2025 |
| Easy Consultants Ltd | Information & communication | 2021 |
| Easy Glass and Glazing Ltd | Construction | 2019 |
| Easy Green Homes Ltd | Construction | 2019 |
| Easy Healthcare Ltd | Health & social care | 2016 |
| Easy Services Limited | Wholesale & retail | 2022 |
| Easyacesslimited Limited | Health & social care | 2022 |
| Easybuy Essentials Ltd | Wholesale & retail | 2025 |
| Easycare Business Rental Services Limited | Real estate | 2006 |
| Easyel Wellness Ltd | Wholesale & retail | 2025 |
| Easyfix Holidays Ltd | Real estate | 2026 |
| Easyfix Solutions Limited | Construction | 2015 |
| Easymove Homes Limited | Construction | 2002 |
| Eats & Treats Oldham Ltd | Hospitality | 2025 |
| Eats Fresh Limited | Hospitality | 2026 |
| Eatwaze Ltd | Wholesale & retail | 2023 |
| Eazycredithire Limited | Administrative & support | 2021 |
| EB Roofing & Construction Ltd | Construction | 2017 |
| EBB App Ltd | Information & communication | 2021 |
| Ebelldistrubutions Ltd | Wholesale & retail | 2026 |
| Ebenezer House Dental Care Limited | Health & social care | 2009 |
| Ebes Group Ltd | Construction | 2026 |
| Ebfire Ltd | Construction | 2025 |
| Ebirdy Tech Nest Ltd | Information & communication | 2025 |
| Ebis Management Services Limited | Professional & scientific | 2025 |
| Ebonies Ltd | Hospitality | 2026 |
| EBS (North West) Limited | Manufacturing | 2022 |
| EC Domestic & Commercial Cleaning Services Ltd | Administrative & support | 2024 |
| Ecaz Ltd | Construction | 2022 |
| Ecco Blinds Ltd | Construction | 2022 |