| DPH OL1 Limited | Real estate | 2024 |
| DPM Groundwork Ltd | Construction | 2019 |
| DPU Limited | Professional & scientific | 2023 |
| DQ Transport Limited | Other services | 2011 |
| DR AHM Properties Ltd | Real estate | 2026 |
| DR Equity Limited | Real estate | 2026 |
| DR Kershaw's Hospice | Health & social care | 2004 |
| DR MN Derm Ltd | Health & social care | 2026 |
| DR Nadia Saleem Limited | Health & social care | 2025 |
| DR Naseem Consulting Limited | Health & social care | 2021 |
| DR Rupinder Kaler Limited | Health & social care | 2025 |
| DR SG Your Best Self Ltd | Other services | 2022 |
| DR T Friedman Ltd | Health & social care | 2013 |
| DR. Kershaw's Hospice (Trading) Limited | Health & social care | 2004 |
| DR. Rebecca Aesthetics & Medical Ltd | Health & social care | 2018 |
| DR7 Ltd | Wholesale & retail | 2024 |
| DRA Corporation Ltd | Wholesale & retail | 2020 |
| Draft Fabrications Limited | Manufacturing | 2015 |
| Dragon Kilns Limited | Manufacturing | 2004 |
| Dragon NW Ltd | Information & communication | 2013 |
| Dransfield Property Development Limited | Construction | 2024 |
| Dransfields Engineering Services Limited | Professional & scientific | 1989 |
| Dransfields Holdings (UK) Limited | Financial services | 2013 |
| Dream Big Sports Ltd | Administrative & support | 2016 |
| Dream Clean by Simina Limited | Administrative & support | 2025 |
| Dream Day OUT Limited | Other services | 2019 |
| Dream Developments Northwest Ltd | Households | 2021 |
| Dream Distributions Ltd | Wholesale & retail | 2023 |
| Dream Trading (UK) Limited | Wholesale & retail | 2015 |
| Dream Traveller Tales Ltd | Information & communication | 2018 |
| Dreamhomesuk Limited | Construction | 2022 |
| Dreamilux Ltd | Manufacturing | 2025 |
| Dreamland Mattress Factory Ltd | Manufacturing | 2023 |
| Dreams Digital Ltd | Professional & scientific | 2023 |
| Dreams Trading Ltd | Wholesale & retail | 2021 |
| Dreamy Lashes Ltd | Wholesale & retail | 2024 |
| Dreamzone Bedding Ltd | Wholesale & retail | 2020 |
| Drive Away Manchester Limited | Wholesale & retail | 2021 |
| Drive Away Motors NW Ltd | Wholesale & retail | 2026 |
| Drive Club School of Motoring Ltd | Administrative & support | 2016 |
| Drive Spark Limited | Wholesale & retail | 2024 |
| Drive-Tek Limited | Extraterritorial | 2013 |
| DRIVE4ME Ltd | Transport & logistics | 2019 |
| Drivehaus Ltd | Wholesale & retail | 2025 |
| Driveino Ltd | Information & communication | 2026 |
| Driven Motor Group Ltd | Manufacturing | 2026 |
| Driver Driven Training Limited | Education | 2011 |
| Driveshine Ltd | Administrative & support | 2016 |
| DRJ Property Investment Limited | Real estate | 2023 |
| Drogan Consultants Ltd | Professional & scientific | 2023 |
| Dronescopex Ltd | Professional & scientific | 2025 |
| Dronsfields Holdings Limited | Financial services | 2019 |
| Dronsfields Limited | Wholesale & retail | 2005 |
| Dronsfields Worldwide Limited | Wholesale & retail | 2000 |
| Dropx Couriers Ltd | Transport & logistics | 2026 |
| Drovars Ltd | Construction | 2024 |
| DRS Advising Ltd | Professional & scientific | 2009 |
| DRS Advisory Ltd | Professional & scientific | 2024 |
| DRS Consultants Ltd | Professional & scientific | 2009 |
| DRS Insolvency Ltd | Administrative & support | 2019 |
| DRS Legal Ltd | Professional & scientific | 2024 |
| Drury Lane Auto Services Ltd | Wholesale & retail | 2022 |
| Druvo Ltd | Wholesale & retail | 2025 |
| Dryaged Ltd | Wholesale & retail | 2019 |
| DS Garden Services Ltd | Administrative & support | 2026 |
| DS Ladhani Ltd | Wholesale & retail | 2023 |
| DS Landscaping & Driveways Ltd | Administrative & support | 2026 |
| DS Property and Landscaping Ltd | Administrative & support | 2026 |
| Dsfr Reality Group Ltd. | Professional & scientific | 2013 |
| Dsgnuk Ltd. | Information & communication | 2016 |
| DSI Electrical Ltd | Construction | 2023 |
| DSK Homes Ltd | Real estate | 2026 |
| DSP 1 Ltd | Wholesale & retail | 2025 |
| DSP Heights Ltd | Construction | 2024 |
| DT Business Services Limited | Professional & scientific | 2024 |
| DT Investments (Yorks) Limited | Real estate | 2021 |
| DT Plastering Solutions Ltd | Construction | 2025 |
| DT Plumbing (NW) Ltd | Construction | 2016 |
| DT Services (Hull) Limited | Manufacturing | 2013 |
| DTC Access & Maintenance Ltd | Transport & logistics | 2020 |
| DTE Surveying Limited | Professional & scientific | 2012 |
| DTP Commercial Ltd | Real estate | 2020 |
| DUA H Abbas Ltd | Wholesale & retail | 2023 |
| DUA Legacy Investments Limited | Construction | 2025 |
| Duaa Healthcare Ltd | Health & social care | 2021 |
| Dubai Coffee Ltd | Hospitality | 2019 |
| Duel Solutions Ltd | Professional & scientific | 2024 |
| Duffy Decorators Ltd | Construction | 2019 |
| Duke Street Boutique Hotel Limited | Hospitality | 2019 |
| Duke Street Motors (Shaw) Ltd | Wholesale & retail | 2021 |
| DUM Holdings Limited | Transport & logistics | 2024 |
| Dumi Limited | Health & social care | 2016 |
| Duncan's of Oldham Limited | Transport & logistics | 1990 |
| Dunealey Limited | Manufacturing | 2019 |
| Dungarvan Ltd | Real estate | 2003 |
| Dunroe Construction Services Ltd | Professional & scientific | 2013 |
| Dunscroft Garage Limited | Wholesale & retail | 2017 |
| Dunwood Livery Yard Ltd | Arts & recreation | 2025 |
| Duri Products Ltd | Extraterritorial | 2017 |
| Durus Security Limited | Administrative & support | 2012 |