| Seahorse Trading Ltd | Construction | 2025 |
| Seaside Town Properties Ltd | Real estate | 2024 |
| SEB Healthcare Ltd | Administrative & support | 2023 |
| Sebastian Efraim Transport Ltd | Transport & logistics | 2025 |
| Sector 22 Ltd | Information & communication | 2020 |
| Seed Megastore Ltd | Wholesale & retail | 2018 |
| Seemore Energy Limited | Administrative & support | 2022 |
| Sehgal & Ghag Investment Limited | Real estate | 2020 |
| Sehgal & Mutta Investment Limited | Real estate | 2021 |
| Sehgal Consultancy Limited | Professional & scientific | 2021 |
| Sehgal Group Ltd | Real estate | 2020 |
| Sekhon Property Dealer Ltd | Real estate | 2024 |
| SEL Property Management LLP | | 2021 |
| Selasi MAX Services Ltd | Administrative & support | 2017 |
| Select Cars Nuneaton Limited | Wholesale & retail | 2025 |
| Seltech Ltd | Wholesale & retail | 2025 |
| SEM Automotion Ltd | Manufacturing | 2023 |
| Sence RPC Limited | Real estate | 2023 |
| Send IT App Ltd | Transport & logistics | 2025 |
| Sendplan Ltd | Education | 2021 |
| Sensbio Ltd | Wholesale & retail | 2026 |
| Seppy Limited | Wholesale & retail | 2022 |
| Sequallity Limited | Information & communication | 2005 |
| Seratar Property Ltd | Households | 2026 |
| Serenith Ltd | Health & social care | 2025 |
| Serenity Support & Care Agency Ltd | Health & social care | 2023 |
| Sergo Care Limited | Other services | 2019 |
| Serine Limited | Manufacturing | 2026 |
| Serren Studios Ltd | Arts & recreation | 2025 |
| Servare Vitas Ltd | Health & social care | 2020 |
| Servibox Ltd | Manufacturing | 2025 |
| Sese & Semi Ltd | Real estate | 2025 |
| Sevenstars Property Ltd | Real estate | 2026 |
| Seventyne Limited | Real estate | 1982 |
| Seymour Holdings (Nuneaton) Limited | Real estate | 2018 |
| Seyrek Barber Limited | Other services | 2019 |
| SFB Accountants Ltd | Professional & scientific | 2021 |
| SFB Consultants Limited | Professional & scientific | 2003 |
| SFB Group (Holdings) Limited | Financial services | 2011 |
| SFB Group Limited | Professional & scientific | 2015 |
| Sfex Event Solutions Ltd | Professional & scientific | 2019 |
| SFH Ground Works Ltd | Professional & scientific | 2026 |
| SFP Group Ltd | Construction | 2016 |
| SG Green Life Ltd | Wholesale & retail | 2023 |
| SG Licensing Ltd | Professional & scientific | 2016 |
| SH Active Sports Limited | Education | 2021 |
| Shadow Moon Limited | Professional & scientific | 2011 |
| Shadowmaine Maine Coons Ltd | Agriculture & fishing | 2025 |
| Shady Blinds Ltd | Manufacturing | 2018 |
| Shahara Taxi Limited | Transport & logistics | 2021 |
| Shala Health Limited | Health & social care | 2023 |
| Shanda Capital Limited | Financial services | 2024 |
| Shared Wisdom Limited | Professional & scientific | 2019 |
| SHARK3D Ltd | Professional & scientific | 2022 |
| Shaun G Consultant Limited | Transport & logistics | 2025 |
| SHE Kicks Academy CIC | Education | 2023 |
| SHE Sells Socials Ltd | Professional & scientific | 2024 |
| Shefcut Tool & Engineering Limited | Extraterritorial | 1976 |
| Sheffield Cable Water SKI Ltd | Arts & recreation | 2012 |
| Sheila's Destiny Limited | Health & social care | 2019 |
| Sheldons Electrical & Plumbing Limited | Construction | 2011 |
| Shelly’S Hair Ltd | Other services | 2018 |
| Shenton (Nuneaton) Estate Company | Real estate | 1950 |
| Sheqoda Systems Limited | Information & communication | 2025 |
| Sheridan Accounting Solutions Limited | Professional & scientific | 2009 |
| Sheridan Business Solutions Ltd | Information & communication | 2021 |
| Sherlok Homes Ltd | Real estate | 2022 |
| Sherrington Services Ltd | Administrative & support | 2026 |
| Ship Happens Wholesalers Ltd | Wholesale & retail | 2026 |
| Shipp Properties Ltd | Real estate | 2018 |
| Shiraz Chhibu Limited | Extraterritorial | 2025 |
| Shirin Homes Limited | Real estate | 2019 |
| Shivom News Limited | Wholesale & retail | 2005 |
| Shoe Tecnik (UK) Limited | Wholesale & retail | 2000 |
| Shopmobility (Nuneaton & Bedworth) Ltd. | Other services | 2004 |
| Shopnature Ltd | Wholesale & retail | 2023 |
| Shraddha Motors Limited | Wholesale & retail | 2024 |
| Shubec Ltd | Transport & logistics | 2018 |
| Shuku Limited | Households | 2020 |
| Shupe Ltd | Other services | 2017 |
| Shwing Sweets Ltd | Wholesale & retail | 2026 |
| SIA Security Services Limited | Other services | 2022 |
| Sibandabros Ltd | Wholesale & retail | 2025 |
| Sibson Mill Properties Limited | Real estate | 1961 |
| SID Properties Limited | Real estate | 2016 |
| Sient Maya Drylining Limited | Construction | 2010 |
| Sigma Seal Limited | Construction | 2022 |
| Sign and Graphics Services (Birmingham) Limited | Professional & scientific | 2012 |
| Sign to Sign (Nuneaton) Limited | Administrative & support | 2016 |
| Signature Clean Group Midlands Ltd | Administrative & support | 2026 |
| Signature Spa Treatments by Suraiya Ltd | Other services | 2022 |
| Silca Limited | Wholesale & retail | 1990 |
| Silly Car Repairs Ltd | Wholesale & retail | 2025 |
| Silva Landscapes Ltd | Administrative & support | 2023 |
| Silva Lingerie Ltd | Wholesale & retail | 2025 |
| Silver Birch Court Management Company Limited | Households | 2006 |
| Silver Delphin Ltd | Wholesale & retail | 2022 |
| Silverback Racing UK Limited | Wholesale & retail | 2025 |
| Silverline Roofing Solutions Ltd | Construction | 2025 |
| Silverlings Limited | Wholesale & retail | 2018 |