| Sofsys Consulting Ltd | Information & communication | 2019 |
| Soft Answers Limited | Information & communication | 2025 |
| Soft Aqua Systems Limited | Administrative & support | 2012 |
| Soft Play Enterprise Limited | Manufacturing | 2018 |
| Soft Service NG7 Ltd | Administrative & support | 2024 |
| Softclue Data Empowerment CIC | Information & communication | 2025 |
| Softclue Technologies Ltd | Information & communication | 2026 |
| Softgular Consultancy Limited | Real estate | 2015 |
| Softqa Limited | Information & communication | 1997 |
| Software Company Direct Ltd | Wholesale & retail | 2024 |
| Software Into Action Limited | Information & communication | 1999 |
| Software Medical Informatics Limited | Information & communication | 1997 |
| Software Strategy Tools and Consulting Limited | Information & communication | 2018 |
| Softwaredome Ltd | Information & communication | 2021 |
| Softwaring Ltd | Information & communication | 2019 |
| Sogalton Ltd | Wholesale & retail | 2025 |
| Sogwa Limited | Health & social care | 2022 |
| Sohail & Sons Ltd | Wholesale & retail | 2020 |
| Sohail Nasti Productions Ltd | Information & communication | 2021 |
| Sohal Brothers Limited | Wholesale & retail | 1998 |
| Sohal International Ltd | Wholesale & retail | 2015 |
| Soham & Dhruv Ltd | Real estate | 2020 |
| Sohawon Properties Limited | Real estate | 2019 |
| Soilandleaf Ltd | Agriculture & fishing | 2026 |
| Soiza Property Limited | Other services | 2018 |
| Sojoko Enterprises Ltd | Professional & scientific | 2017 |
| Sojourn Resorts Ltd | Hospitality | 2018 |
| Sokhi Enterprises Limited | Real estate | 2002 |
| Sokyo Hyde Limited | Wholesale & retail | 2025 |
| SOL Systems Ltd | Information & communication | 2025 |
| Sola Fit (UK) Limited | Professional & scientific | 2011 |
| Solace UK Accommodations Limited | Real estate | 2025 |
| Solair Limited | Manufacturing | 1993 |
| Solaire Logistics Ltd | Transport & logistics | 2021 |
| Solairehandymen Ltd | Administrative & support | 2024 |
| Solar Connect Solutions Ltd | Professional & scientific | 2025 |
| Solar Flare Investment Ltd | Wholesale & retail | 2021 |
| Solar Innovations Limited | Construction | 2025 |
| Solar Peak Renewables Ltd | Construction | 2024 |
| Solar Renewables and Importations Ltd | Professional & scientific | 2023 |
| Solar Salvage Limited | Professional & scientific | 2023 |
| Solar Star Property Group Limited | Real estate | 2022 |
| Solara Grace Ltd | Wholesale & retail | 2024 |
| Solarcrowdin Ltd | Manufacturing | 2020 |
| Solarpointscircuits Ltd | Transport & logistics | 2019 |
| Solcare (Broxtowe & Erewash) Ltd | Health & social care | 2015 |
| Sold OUT Stock Limited | Wholesale & retail | 2019 |
| Soldonmydrive.Com Ltd | Information & communication | 2023 |
| Sole-Care Limited | Health & social care | 2022 |
| Solea Global Ltd | Wholesale & retail | 2026 |
| Soleil Universal Networks Ltd | Information & communication | 2022 |
| Solent Metals Ltd | Water & waste | 2011 |
| Solent Ridge Ltd | Wholesale & retail | 2026 |
| Solent Surgery Ltd | Professional & scientific | 2013 |
| Soleo Products Limited | Wholesale & retail | 2024 |
| Soletto Eyewear Ltd | Wholesale & retail | 2023 |
| Solid Aspect UK Limited | Wholesale & retail | 2023 |
| Solid Grappling Ltd | Arts & recreation | 2023 |
| Solid Healthcare Ltd | Administrative & support | 2022 |
| Solid Systems Global Limited | Information & communication | 2012 |
| Solitude Dynamics Limited | Real estate | 2025 |
| Sollich (UK) Ltd. | Wholesale & retail | 1996 |
| Sollys SB Limited | Hospitality | 2026 |
| Solo and Co (Nottm) Limited | Arts & recreation | 2005 |
| Solo Audio Accessories Limited | Manufacturing | 1980 |
| Solo Gains Limited | Wholesale & retail | 2024 |
| Solo Homes Limited | Real estate | 2017 |
| Solo Leads Limited | Professional & scientific | 2005 |
| Solo Software Ltd | Information & communication | 2020 |
| Solo Support Services Ltd | Health & social care | 2010 |
| Solo Tape Limited | Wholesale & retail | 2002 |
| Sologub Limited | Transport & logistics | 2021 |
| Solomon Alfie Proficiency Limited | Professional & scientific | 2021 |
| Solstice Risk Advisory Ltd | Professional & scientific | 2025 |
| Solsure Electrical Ltd | Construction | 2025 |
| Solution Forge Service Ltd | Hospitality | 2019 |
| Solution Supplies Limited | Other services | 2009 |
| Solution Tank Limited | Construction | 2003 |
| Solutions & Solutions Limited | Administrative & support | 2023 |
| Solutions Accountants and Financial Services Ltd | Professional & scientific | 2012 |
| Solutions AK Ltd | Professional & scientific | 2020 |
| Solutions Cloud Limited | Information & communication | 2019 |
| Solutions Diverse Holdings Limited | Arts & recreation | 2020 |
| Solutions Diverse Ltd. | Arts & recreation | 1999 |
| Solutions for Accounting Limited | Information & communication | 1998 |
| Solutions for Retail Brands Limited | Information & communication | 2006 |
| Solutions Today Limited | Information & communication | 2020 |
| Solvabl Ltd | Wholesale & retail | 2020 |
| Solvdd UK Ltd | Professional & scientific | 2025 |
| Solvenergy Limited | Construction | 2023 |
| Solvexa Green Energy Holdings Ltd | Construction | 2025 |
| Solvexa Green Energy Ltd | Professional & scientific | 2006 |
| Solving More Ltd | Administrative & support | 2023 |
| SOM Investments Limited | Real estate | 2025 |
| Soma Libra Limited | Manufacturing | 2023 |
| Somatic Leadership Group Ltd | Professional & scientific | 2026 |
| Somersby Consulting Limited | Professional & scientific | 2010 |
| Somerset Creameries Group Limited | Manufacturing | 2005 |
| Somerset Creameries Limited | Professional & scientific | 1941 |
| Something Blue Weddings Limited | Wholesale & retail | 2013 |