| Sherwood Universal Limited | Manufacturing | 2012 |
| Sherwood Urology Ltd | Health & social care | 2019 |
| Sherwood Vale Holdings Limited | Administrative & support | 2020 |
| Shetliffe Group Holdings Limited | Financial services | 2020 |
| Shewolves Productions CIC | Education | 2022 |
| Sheyilaconsult Ltd | Administrative & support | 2017 |
| Shezambi and Co Ltd | Health & social care | 2014 |
| SHF39 Ltd | Wholesale & retail | 2025 |
| Shhhip Ltd | Administrative & support | 2020 |
| Shiba Ltd | Wholesale & retail | 2021 |
| Shie Kayres Limited | Administrative & support | 2023 |
| Shield and Gleam Services Limited | Construction | 2024 |
| Shield Cars TA Ltd | Wholesale & retail | 2026 |
| Shield Electrical Solutions Ltd. | Construction | 2024 |
| Shield Security & Electrical Limited | Administrative & support | 2003 |
| Shielded Services Ltd | Administrative & support | 2024 |
| Shifaa Medical Company Ltd | Health & social care | 2025 |
| Shifapath Limited | Health & social care | 2025 |
| Shift Innovation Ltd | Professional & scientific | 2018 |
| Shiftd Ltd | Wholesale & retail | 2018 |
| Shiftd Media Ltd | Extraterritorial | 2018 |
| Shifting Your Mindset | Hospitality | 2021 |
| Shifts to Success Ltd | Education | 2017 |
| Shiggins Civils Ltd | Construction | 2018 |
| Shikokungu Care Ltd | Health & social care | 2013 |
| Shiloh Care Ltd | Health & social care | 2021 |
| Shilton Family Homes Ltd | Extraterritorial | 2024 |
| Shim Care Limited | Health & social care | 2025 |
| Shine Enterprise Ltd | Health & social care | 2026 |
| Shine Multi Academy Trust | Education | 2012 |
| Shine Talent Management Limited | Arts & recreation | 2020 |
| Shinequest Cleaning Services Limited | Administrative & support | 2025 |
| Shining Bathroom Limited | Wholesale & retail | 2026 |
| Shining Light Investments Limited | Real estate | 2025 |
| Shinnate Care Limited | Health & social care | 2020 |
| Shinsei Engineering Ltd | Professional & scientific | 2019 |
| Shiny Bees Ltd | Health & social care | 2025 |
| Shiny by Alin Ltd | Administrative & support | 2025 |
| Shiny Games Ltd | Wholesale & retail | 2015 |
| Shiny Hand Car Wash Notts Ltd | Administrative & support | 2025 |
| Shiny Show Ltd | Other services | 2025 |
| Shio Street Food Limited | Hospitality | 2025 |
| Shipday Logistics Ltd | Hospitality | 2022 |
| Shipley Blinds Limited | Construction | 2003 |
| Shipley Commercial Property Co Ltd | Professional & scientific | 2018 |
| Shipley Holdings Limited | Extraterritorial | 2015 |
| Shipley Property Company Ltd | Real estate | 2005 |
| Shippersworld Limited | Transport & logistics | 2017 |
| Shippex Ltd | Wholesale & retail | 2019 |
| Ships Property Holdings Ltd | Real estate | 2017 |
| Shipstones Beer Company Ltd | Manufacturing | 2013 |
| Shipwreck Kayaks Ltd | Wholesale & retail | 2020 |
| Shiraz Constraction Ltd | Construction | 2026 |
| Shiraz Properties Limited | Real estate | 2024 |
| Shire Burrows Limited | Real estate | 2026 |
| Shirebrook DIY Home & Garden Ltd | Wholesale & retail | 2020 |
| Shirecare Limited | Health & social care | 2016 |
| Shires Motorcycle Training Limited | Education | 2005 |
| Shirley Longford Business Services Limited | Professional & scientific | 2016 |
| Shiro Stand Ltd | Professional & scientific | 2024 |
| Shirohstarlight Healthcare Ltd | Administrative & support | 2022 |
| Shirtcliffe and Co Limited | Extraterritorial | 2019 |
| Shirtysomething Limited | Administrative & support | 2006 |
| Shisha Corner Ltd | Wholesale & retail | 2021 |
| Shiso Software Limited | Information & communication | 2023 |
| Shisu Co Limited | Hospitality | 2025 |
| Shiva Stores Ltd | Wholesale & retail | 2024 |
| Shivago Psychology Ltd. | Education | 2017 |
| Shivah Food Ltd | Hospitality | 2025 |
| Shivan Kovil Nottingham Ltd | Real estate | 2024 |
| Shivay Shakti Limited | Hospitality | 2025 |
| Shoaib Khan Consulting Ltd | Construction | 2022 |
| Shoaib Khan Limited | Wholesale & retail | 2025 |
| Shoal Consulting Limited | Information & communication | 2009 |
| Shobu Ramen Limited | Hospitality | 2025 |
| Shoby Holdings Limited | Financial services | 2020 |
| Shoby Investments Limited | Financial services | 2015 |
| Shoby Priory Agricultural Limited | Agriculture & fishing | 2016 |
| Shoby Properties Limited | Real estate | 2000 |
| Shoby Recruitment Ltd | Administrative & support | 2016 |
| Shoby Residential Limited | Real estate | 2018 |
| Shock & Shape Ltd | Arts & recreation | 2023 |
| Shoes by RS Ltd | Wholesale & retail | 2026 |
| Shola and Spice Ltd | Hospitality | 2026 |
| Shonarani Limited | Other services | 2019 |
| Shooter Consultancy Ltd | Administrative & support | 2011 |
| Shop 4 Sofas Limited | Wholesale & retail | 2003 |
| Shop at Last Enterprise Ltd | Wholesale & retail | 2023 |
| Shop Online Cheap Ltd | Wholesale & retail | 2025 |
| Shop Supplies 4 U Limited | Wholesale & retail | 2014 |
| Shopfitting Joinery Midlands Ltd | Manufacturing | 2014 |
| Shopmakers Limited | Manufacturing | 2007 |
| Shopwithcs Ltd | Wholesale & retail | 2023 |
| Shore to Please Ltd | Wholesale & retail | 2018 |
| Shoreline Group Limited | Construction | 2024 |
| Shores Tech Ltd | Information & communication | 2019 |
| Shoreway Business Support Ltd | Professional & scientific | 2022 |
| Short Stitch Ltd | Manufacturing | 2021 |
| Short-Sided Ltd | Other services | 2023 |
| Shortcat Drive Ltd | Transport & logistics | 2018 |