| Scorpio VIP Ltd | Wholesale & retail | 2024 |
| Scorpion Project Solutions Limited | Construction | 2016 |
| Scotcher Interiors Limited | Administrative & support | 2016 |
| Scott Barlow Limited | Wholesale & retail | 2004 |
| Scott Bentley Associates Limited | Health & social care | 2010 |
| Scott Construction Civil Engineering Limited | Construction | 2015 |
| Scott FRY Limited | Professional & scientific | 2006 |
| Scott Gorman Ltd | Construction | 2015 |
| Scott Heating Solutions Limited | Construction | 2023 |
| Scott Inspections and Access Ltd | Professional & scientific | 2022 |
| Scott Investment Group Ltd | Financial services | 2022 |
| Scott INVESTMENT1 Limited | Real estate | 2026 |
| Scott INVESTMENT2 Limited | Real estate | 2026 |
| Scott Johnson Foundation CIC | Arts & recreation | 2021 |
| Scott Martin Rentals Limited | Real estate | 2024 |
| Scott Mount Limited | Professional & scientific | 2018 |
| Scott Neil Limited | Professional & scientific | 1998 |
| Scott-Smith Consultancy Ltd | Health & social care | 2018 |
| Scout & Cast Limited | Other services | 2021 |
| Scout 1842 Limited | Real estate | 2022 |
| Scoutedbyjr (MA) Ltd | Administrative & support | 2020 |
| SCP Services Ltd | Information & communication | 2023 |
| SCR Carpets Limited | Wholesale & retail | 2025 |
| Scrapmetaluk Ltd | Wholesale & retail | 2022 |
| Scratch Analytics Limited | Information & communication | 2023 |
| Scratch Creative London Ltd | Professional & scientific | 2020 |
| Scratch Golf Range Limited | Arts & recreation | 2024 |
| Screen Photography Ltd | Professional & scientific | 2013 |
| Screenlytic Limited | Information & communication | 2025 |
| Screenstar Media Limited | Information & communication | 2002 |
| Screveton (Old Hall Gardens) Residents Management Company Ltd | Households | 2019 |
| Screveton Limited | Professional & scientific | 2013 |
| Screwfast Foundations Limited | Construction | 2000 |
| Screwtape Limited | Information & communication | 2008 |
| Scriptbyjaymal Ltd | Information & communication | 2024 |
| Scription Ltd. | Information & communication | 2020 |
| Scriptwriting East Midlands Ltd | Information & communication | 2024 |
| Scroll Studios Ltd | Professional & scientific | 2024 |
| Scrub IT and Clean IT Recruitment Ltd | Transport & logistics | 2025 |
| Scruffy Dog Games Ltd | Information & communication | 2025 |
| Scrutiny Holdings Ltd | Financial services | 2025 |
| Scrutiny Media Ltd | Information & communication | 2025 |
| SCS Cosmetics Ltd | Extraterritorial | 2023 |
| SCS RG4 Mgmt Ltd | Hospitality | 2026 |
| SCS Technology Solutions Limited | Information & communication | 2000 |
| Sctf-Uk Limited | Education | 2010 |
| Sculpture Salon (UK) Limited | Other services | 2009 |
| Scunthorpe V.E. Limited | Other services | 1997 |
| Scurlage Ltd | Hospitality | 2022 |
| SCW Building Company Ltd | Construction | 2015 |
| Scyles Ltd | Wholesale & retail | 2025 |
| SD Aerotech Limited | Manufacturing | 2013 |
| SD Builders Ltd | Construction | 2022 |
| SD Cubed Ltd | Information & communication | 2022 |
| SD Games Ltd | Information & communication | 2021 |
| SD Jointing Services Limited | Construction | 2019 |
| SD Nottingham Ltd | Hospitality | 2023 |
| SD Shop Fitting Limited | Manufacturing | 2016 |
| SDA Global Ltd | Other services | 2018 |
| SDA United Holdings Limited | Other services | 2023 |
| Sdalc Limited | Information & communication | 2013 |
| SDB Projects Limited | Construction | 2015 |
| SDC Automotive Ltd | Wholesale & retail | 2021 |
| Sddv Holdings Limited | Financial services | 2022 |
| Sdee Properties Limited | Real estate | 2018 |
| SDG Caterers Limited | Hospitality | 2024 |
| SDG Enterprises Limited | Hospitality | 2024 |
| SDG Property Services Limited | Real estate | 2017 |
| SDG Vascular Ltd | Health & social care | 2019 |
| Sdgfilmfest Ltd | Information & communication | 2023 |
| SDH Ventures Ltd | Hospitality | 2015 |
| SDL Auctions Limited | Real estate | 2011 |
| SDL BTR Developments Limited | Financial services | 2019 |
| SDL BTR Holdco Limited | Financial services | 2023 |
| SDL BTR Management Limited | Real estate | 2010 |
| SDL Group Services Limited | Professional & scientific | 2017 |
| SDL Retail Ltd | Wholesale & retail | 2020 |
| Sdls Holdings Limited | Financial services | 2025 |
| SDM (Nottingham) Ltd | Administrative & support | 2018 |
| SDM Systems Limited | Information & communication | 2014 |
| SDN Design Ltd. | Professional & scientific | 2015 |
| SDP Asset Management Ltd | Extraterritorial | 2015 |
| SDS Finance Ltd | Professional & scientific | 2019 |
| SDS Plastering and Drylining Limited | Construction | 2026 |
| SDS Trading Limited | Wholesale & retail | 2014 |
| SDT Solutions Limited | Construction | 2025 |
| SDV Properties Limited | Real estate | 2022 |
| SE Painting & Decorating Services Ltd | Construction | 2021 |
| SE7EN Services Limited | Other services | 2022 |
| Sea Cleaning Ltd | Transport & logistics | 2020 |
| Sea Energy Associates Limited | Professional & scientific | 2008 |
| Sea Otter Limited | Extraterritorial | 2018 |
| Sea Soul Ltd | Health & social care | 2015 |
| Sea Star Creative Design Ltd | Wholesale & retail | 2020 |
| Sea Wolf Property Limited | Real estate | 2020 |
| Sea-Esta Lets Ltd | Hospitality | 2023 |
| Seabright Contracts Limited | Manufacturing | 2016 |
| Seachievementgroup Ltd | Administrative & support | 2026 |
| Seacrest Fish Bar Limited | Hospitality | 2024 |
| Seacroft Ltd | Wholesale & retail | 2013 |