| SB Outdoor Living Ltd | Construction | 2021 |
| SB Real Estates Holdings Ltd | Real estate | 2026 |
| SB Residences Ltd | Real estate | 2022 |
| SB RTM Company Limited | Households | 2020 |
| SB Smartworking Services Ltd. | Administrative & support | 2018 |
| SB Trading PTY Ltd | Wholesale & retail | 2025 |
| SB15 Limited | Professional & scientific | 2025 |
| SB4 Management Ltd | Administrative & support | 2025 |
| SBC Nottingham Ltd | Wholesale & retail | 2024 |
| SBK Housing Limited | Real estate | 2026 |
| SBK Nottingham Properties Limited | Real estate | 2021 |
| SBL Consulting Limited | Professional & scientific | 2025 |
| SBM Surfacing Ltd | Construction | 2018 |
| SBR Collective Entertainment Ltd | Arts & recreation | 2026 |
| SBR Events Limited | Arts & recreation | 2013 |
| SBS Europa Limited | Transport & logistics | 2008 |
| SBS PMS Ltd | Information & communication | 2016 |
| SBS Property Services Ltd | Construction | 2005 |
| Sbss Properties Limited | Real estate | 2017 |
| Sbtdsn Ltd | Information & communication | 2023 |
| SBY Garage Ltd | Wholesale & retail | 2023 |
| SBZ Restaurant Limited | Hospitality | 2018 |
| SC & JLD Properties Limited | Real estate | 2002 |
| SC & K Matthews Property Limited | Households | 2015 |
| SC & PS Saunders Limited | Wholesale & retail | 2013 |
| SC Bakery Solutions Limited | Professional & scientific | 2025 |
| SC GAS Services Limited | Construction | 2017 |
| SC Hardy Estates Limited | Households | 2023 |
| Scaffolding and Working at Height Consultancy Ltd | Professional & scientific | 2024 |
| Scale Africa Limited | Administrative & support | 2026 |
| Scale Swimming Ltd | Manufacturing | 2019 |
| Scalesmart Solutions Limited | Information & communication | 2025 |
| Scaling Infrastructure Management Limited | Construction | 2023 |
| Scam Guardian Services Ltd | Information & communication | 2018 |
| Scampi Cat Investments Ltd | Financial services | 2020 |
| Scan Belts Limited | | 1976 |
| Scape Consulting Limited | Professional & scientific | 2026 |
| Scape Group Limited | Professional & scientific | 2005 |
| Scape Investments Limited | Administrative & support | 2014 |
| Scape Limited | Professional & scientific | 2013 |
| Scape Procure Limited | Professional & scientific | 2016 |
| Scape Reinvest Limited | Administrative & support | 2013 |
| Scape Venture Limited | Professional & scientific | 2011 |
| Scarlet Hudson Ltd | Professional & scientific | 2017 |
| Scarlet Hudson Property Ltd | Real estate | 2022 |
| Scarlett Properties Management UK Ltd | Households | 2020 |
| Scarpgold Limited | Wholesale & retail | 1993 |
| Scarrington Developments Limited | Construction | 2008 |
| Scarsdalevets LLP | | 2009 |
| Scary Mary Cards Limited | Manufacturing | 2012 |
| Scarycaravan Studios Ltd | Professional & scientific | 2021 |
| Scattergood Brothers Limited | Administrative & support | 2000 |
| SCB Logistics Ltd | Transport & logistics | 2012 |
| SCC Accountants Limited | Professional & scientific | 2012 |
| SCC Scientific Consulting Company UK Ltd. | Professional & scientific | 2020 |
| SCD Accounting Consultancy Ltd | Professional & scientific | 2026 |
| SCE Sales Training Consulting Limited | Professional & scientific | 2021 |
| Scele Solutions Ltd | Professional & scientific | 2018 |
| Scenarios Software Ltd | Information & communication | 2026 |
| Scene Photography Limited | Professional & scientific | 2004 |
| Scene Setter Ltd | Other services | 2017 |
| Scennie Royals Ltd | Wholesale & retail | 2026 |
| Scented Moments for YOU Ltd | Wholesale & retail | 2023 |
| Scented Studio Ltd | Manufacturing | 2022 |
| Scgh Limited | Financial services | 2015 |
| Schemata Games LLP | | 2026 |
| Schnell Delivery Ltd | Transport & logistics | 2025 |
| Schoeman Estates Ltd | Real estate | 2019 |
| Schofield Construction Consultants Limited | Construction | 2012 |
| Schofield Travel Limited | Transport & logistics | 1990 |
| Scholarsway Travels Ltd | Administrative & support | 2026 |
| Scholartech ICT Services Ltd | Wholesale & retail | 2018 |
| Scholes Environmental Consultancy Limited | Professional & scientific | 2021 |
| School Catering Support Limited | Hospitality | 2008 |
| School of Calisthenics Ltd | Education | 2017 |
| School of Health and Neural Sciences Limited | Professional & scientific | 2005 |
| Schools Direct Limited | Wholesale & retail | 1955 |
| Sci-Comm Consulting Limited | Information & communication | 2017 |
| Sci-Osg Ltd | Professional & scientific | 2021 |
| Science Health YOU Ltd | Hospitality | 2025 |
| Scientific Intelligence Ltd | Professional & scientific | 2020 |
| Scintam Engineering Ltd | Manufacturing | 2021 |
| Scissor Happy Limited | Other services | 2013 |
| Scissyphus Ltd | Administrative & support | 2022 |
| Scitec PMO Limited | Professional & scientific | 2021 |
| SCM Midlands Ltd | Health & social care | 2019 |
| Scooby Mania Limited | Wholesale & retail | 2004 |
| Scooter & Scooterist Limited | Wholesale & retail | 1986 |
| Scooter Media Limited | Information & communication | 2019 |
| Scooters Plus Ltd | Wholesale & retail | 2023 |
| Scope Projects Limited | Real estate | 2005 |
| Scope Property Group UK Ltd | Real estate | 2024 |
| Scope Signs & Technical Services Limited | Administrative & support | 2003 |
| Score Football Camps Limited | Arts & recreation | 2025 |
| Score Football Soccer Schools Limited | Arts & recreation | 2025 |
| Scorewise Finance Ltd | Financial services | 2025 |
| Scoria Limited | Information & communication | 2016 |
| Scorozio Ltd | Transport & logistics | 2016 |
| Scorpdev Ltd | Information & communication | 2019 |
| Scorpio Signs (Nottingham) Limited | Manufacturing | 2000 |