| Empire Service Centre Ltd | Wholesale & retail | 2024 |
| Empire State Developments Ltd | Real estate | 2019 |
| Empleo Community Interest Company | Education | 2013 |
| Employ Co. Limited | Administrative & support | 2025 |
| Employ Recruitment UK Limited | Other services | 2004 |
| Empoke Ltd | Wholesale & retail | 2026 |
| Emporio Barbers-Uk Ltd | Other services | 2024 |
| Emporio Interiors Ltd | Professional & scientific | 2008 |
| Emporior Barbers Ltd | Other services | 2025 |
| Empower Healing CIC | Health & social care | 2025 |
| Empower Health & Performance Ltd | Wholesale & retail | 2024 |
| Empowered Foundations CIC | Education | 2022 |
| Empowered Living Solutions Limited | Health & social care | 2025 |
| Empowering the Youth CIC | Education | 2024 |
| Empowering Through Rhythm CIC | Education | 2024 |
| Empowering Your Future Ltd | Other services | 2023 |
| Empowerment for Heya CIC | Education | 2020 |
| Empowerment Living Ltd | Administrative & support | 2024 |
| Empressa International Ltd | Wholesale & retail | 2025 |
| Emre Property Ltd | Real estate | 2022 |
| Emrise Ltd | Information & communication | 2025 |
| Emrsa Ltd | Wholesale & retail | 2020 |
| EMS (Bulwell) Limited | Manufacturing | 2012 |
| EMS Creations Limited | Administrative & support | 2019 |
| Emsclip Ltd | Wholesale & retail | 2025 |
| Emtacs Accountants Ltd | Professional & scientific | 2011 |
| Emtec Colleges Limited | Education | 2009 |
| Emtec Specialised Services Limited | Education | 2020 |
| Emtelecoms Ltd | Information & communication | 2026 |
| Emtom Fire Safety Ltd | Professional & scientific | 2018 |
| EMW Services Ltd | Other services | 2024 |
| EMW Trade Services Limited | Wholesale & retail | 2016 |
| EMY Trans Limited | Transport & logistics | 2024 |
| EMZ Aesthetics AP Ltd | Education | 2025 |
| EMZ Aesthetics Ltd | Education | 2022 |
| Emzo Retail Ltd | Wholesale & retail | 2023 |
| EN International Ltd. | Wholesale & retail | 2016 |
| EN Kassianidis Ltd | Information & communication | 2012 |
| Enable Physiotherapy Ltd | Other services | 2024 |
| Enable-It Consultancy Limited | Professional & scientific | 2017 |
| Enabling Care Ltd | Administrative & support | 2014 |
| Enactus UK | Education | 2002 |
| Enactus UK Trading Limited | Education | 2013 |
| Enaibel Limited | Information & communication | 2025 |
| Enat Cafe Ltd | Hospitality | 2025 |
| Encarnacao Justo Ltd | Health & social care | 2024 |
| Enchanted Rose Florist Ltd | Wholesale & retail | 2019 |
| Enchanting Moments Nottz CIC | Other services | 2024 |
| Encircle Solutions Limited | Information & communication | 2004 |
| Encompass Logistics Solutions LLP | | 2010 |
| Encompass Print Solutions Holdings Limited | Financial services | 2021 |
| Encompass Print Solutions Limited | Manufacturing | 2006 |
| Encon Associates Limited | Professional & scientific | 2008 |
| Encore Gifts Ltd | Wholesale & retail | 2021 |
| Encore Performing Arts Ltd | Arts & recreation | 2014 |
| Endeavour Group Limited | Financial services | 2015 |
| Endeavour Partners U Ltd | Real estate | 2026 |
| Enderby Detailing & Valeting Limited | Administrative & support | 2022 |
| Enderleigh Mews 2023 Ltd | Households | 2023 |
| Endfield Limited | Financial services | 2005 |
| Endomedical Limited | Health & social care | 2021 |
| Endon Hall Consulting Ltd | Professional & scientific | 2016 |
| Endro Ltd | Financial services | 2025 |
| Endsleigh Consulting Limited | Professional & scientific | 2020 |
| Endurance Sport Consulting Ltd | Arts & recreation | 2026 |
| Endure Gym and Fitness Ltd | Arts & recreation | 2026 |
| Enduring Legacy Limited | Financial services | 2020 |
| Enercomp Limited | Mining & quarrying | 2018 |
| Energi Consulting Services Limited | Professional & scientific | 2005 |
| Energies of the Future Limited | Construction | 2009 |
| Energix Limited | Professional & scientific | 2012 |
| Energy Assessors (Nottingham) Ltd | Professional & scientific | 2007 |
| Energy Bureau Holdings Limited | Administrative & support | 2024 |
| Energy Bureau Ltd | Administrative & support | 2017 |
| Energy Conservation Solutions Consultancy Limited | Professional & scientific | 2009 |
| Energy Developments Limited | Professional & scientific | 2006 |
| Energy Performance and Sustainability Group Limited | Professional & scientific | 2014 |
| Energy Security Strategy Consulting Ltd. | Wholesale & retail | 2025 |
| Energy Street Ltd. | Professional & scientific | 2008 |
| Energy Vending Limited | Wholesale & retail | 2008 |
| Energy X Group Ltd | Construction | 2025 |
| Energytik Developments Limited | Professional & scientific | 2018 |
| Energywize UK Limited | Financial services | 2008 |
| Enerjarden Limited | Information & communication | 2025 |
| Enertech FM Limited | Manufacturing | 2014 |
| Eneyserv Limited | Water & waste | 2014 |
| Eneyserv Properties Limited | Real estate | 2023 |
| Enfield V.E. Limited | Other services | 1996 |
| Engage Communities CIC | Health & social care | 2010 |
| Engage Conservation Ltd | Administrative & support | 2026 |
| Engine Care Solution Ltd | Wholesale & retail | 2025 |
| Engine Exchange Ltd | Manufacturing | 2025 |
| Engine House Theatre Ltd | Arts & recreation | 2010 |
| Engine Mobile Holdings Limited | Financial services | 2019 |
| Engine Parts Direct Limited | Wholesale & retail | 2021 |
| Engine Repair Group Ltd | Professional & scientific | 2025 |
| Engineered Analytics Ltd | Information & communication | 2026 |
| Engineered Moto Tech Ltd | Wholesale & retail | 2024 |
| Engineered Safety Ltd | Professional & scientific | 2025 |
| Engineered Woodwork Ltd | Manufacturing | 2024 |