| Epop AI Limited | Information & communication | 2021 |
| Epos NOW (UK) Ltd | Wholesale & retail | 2011 |
| Epos NOW Ltd | Information & communication | 2017 |
| Epping Facilities Limited | Financial services | 2006 |
| Epsilis Limited | Information & communication | 1999 |
| Epworth PM Limited | Real estate | 2019 |
| EQ Films Ltd | Information & communication | 2006 |
| Equestrian Business Ltd | Information & communication | 2001 |
| Equestrian Tweed Ltd | Wholesale & retail | 2024 |
| Equidigit Ltd | Manufacturing | 2018 |
| Equilibrium Medical Aesthetics Ltd | Health & social care | 2019 |
| Equinox Development Partners Limited | Real estate | 2023 |
| Equinoxed Accounting Ltd | Extraterritorial | 2025 |
| Equinoxed Accounting Services Ltd | Professional & scientific | 2024 |
| Equipment Supply Company (G.Y.) Limited | Wholesale & retail | 1987 |
| Equisan Limited | Administrative & support | 2014 |
| ERA (Norwood) Ltd | Professional & scientific | 2013 |
| Eravista Limited | Manufacturing | 2015 |
| Eres Group Ltd | Manufacturing | 2019 |
| ERG Engineering Limited | Mining & quarrying | 2013 |
| Ergo SUM Services Limited | Construction | 1998 |
| Ergofy Limited | Information & communication | 2016 |
| Ergomedica Limited | Professional & scientific | 2007 |
| Eric V Ltd | Health & social care | 2024 |
| Ericsons Events Limited | Administrative & support | 2021 |
| Ericsons Properties Limited | Real estate | 2021 |
| Ericsons Renovations Limited | Construction | 2025 |
| Erin Barry Photography & Design Limited | Professional & scientific | 2013 |
| ERM (Eastern Region Media) CIC | Arts & recreation | 2011 |
| Ernest Cole Developments Limited | Construction | 2016 |
| Ernest MAY Investments Limited | Financial services | 2026 |
| Ernest MAY Recruitment Limited | Administrative & support | 2024 |
| Erpingham Lodges Limited | Construction | 2017 |
| Erskine Dorrell Ltd | Other services | 2016 |
| Erwinspet Limited | Real estate | 2024 |
| Eryilmaz Limited | Transport & logistics | 2019 |
| ES Motorsport Ltd | Wholesale & retail | 2010 |
| ES Services East Anglia Limited | Administrative & support | 2023 |
| ESA Electrics Ltd | Other services | 2020 |
| Esaens Ltd | Financial services | 2021 |
| Esafe Innovations Limited | Information & communication | 2024 |
| Escape the Movies Ltd | Arts & recreation | 2024 |
| Escape to the Water Ltd | Extraterritorial | 2021 |
| Esco Developments (Blaby) Ltd | Construction | 2022 |
| Esco Developments Ltd | Construction | 2010 |
| Eseotech Limited Ltd. | Wholesale & retail | 2024 |
| Esertas Consultancy Ltd | Administrative & support | 2018 |
| Esher Management Services Limited | Professional & scientific | 1991 |
| Esoteric Group Limited | Construction | 2018 |
| Esoteric Services Group Limited | Construction | 2023 |
| ESP Merchandise Ltd | Manufacturing | 2022 |
| Espalier Property Projects 009 Ltd | Real estate | 2000 |
| Espiritos Lumin Ltd | Wholesale & retail | 2026 |
| ESS Financial Services Limited | Financial services | 2005 |
| Essence Competitions Limited | Administrative & support | 2025 |
| Essence of India Dudley Ltd | Hospitality | 2021 |
| Essence of Indulgence Ltd | Hospitality | 2022 |
| Essential Automation Ltd | Manufacturing | 2013 |
| Essential Controls (Norwich) Ltd | Manufacturing | 2024 |
| Essential Heating Solutions Ltd | Construction | 2021 |
| Essential Oils Online Limited | Wholesale & retail | 2006 |
| Essential Solutions Group Ltd | Financial services | 2022 |
| Essentialsmartliving Ltd | Health & social care | 2023 |
| Essentiamarketing Ltd | Administrative & support | 2017 |
| Essex and Suffolk Dart C.I.C. | Transport & logistics | 2016 |
| Essex CAD Limited | Professional & scientific | 2013 |
| Essex Financial Consultancy Limited | Real estate | 2015 |
| Estately Ltd | Real estate | 2020 |
| Estately Management Ltd | Real estate | 2023 |
| Esteem Hair Limited | Other services | 2015 |
| Estetika Studio Ltd | Other services | 2012 |
| Estiro Ltd | Administrative & support | 2017 |
| Ests Guidelines Ltd | Education | 2025 |
| Estuary Reach Ltd | Households | 2016 |
| Esuccesses Healthcare Group Ltd | Other services | 2020 |
| Eswyn Road Limited | Real estate | 2019 |
| ET AL Jewellery Ltd | Wholesale & retail | 2019 |
| ET Consulting Services Limited | Administrative & support | 2015 |
| Etage Property Ltd | Real estate | 2022 |
| ETC (East Anglia) Limited | Information & communication | 2000 |
| ETC. Films Ltd | Information & communication | 2020 |
| Eternity Cars UK Ltd | Transport & logistics | 2018 |
| Eteron Acle Limited | Real estate | 2022 |
| ETF Electrical Contractors Ltd | Construction | 2025 |
| Ethan Laithwaite Consultancy Ltd | Information & communication | 2024 |
| Ethan Reed Global Trading Limited | Wholesale & retail | 2023 |
| Ethco Ltd | Financial services | 2012 |
| Ethco MP Ltd | Real estate | 2021 |
| Ethos Care Group Limited | Health & social care | 2021 |
| Etits Aero Limited | Manufacturing | 2017 |
| Etms Highways Ltd. | Administrative & support | 2014 |
| Etsaw Ltd | Manufacturing | 2020 |
| ETT Industries Limited | Arts & recreation | 2015 |
| Etude Co Ltd. | Other services | 2021 |
| Eudaemonia Consultancy Ltd | Health & social care | 2023 |
| Eudaemonia Group Ltd | Health & social care | 2025 |
| Eudaemonia Therapies Ltd | Health & social care | 2025 |
| Eugene Trading Investments Ltd | Real estate | 2023 |
| Eunomia 64 Limited | Professional & scientific | 2016 |
| Eureka Management Company Limited | Construction | 2005 |