| Endeavour Enterprises (Norwich) Limited | Real estate | 2016 |
| Endgrain Carpentry & Build Ltd | Construction | 2023 |
| Endolux Limited | Health & social care | 2025 |
| Endosupportuk Ltd | Administrative & support | 2022 |
| Energerry Ltd | Professional & scientific | 2025 |
| Energy Consultancy Ltd | Manufacturing | 2015 |
| Energy Controls and Instrumentation Group Ltd | Construction | 2025 |
| Energy Development Co-Operative Limited | Construction | 1998 |
| Energy Holdco Limited | Professional & scientific | 2012 |
| Energy Rush Ltd | Health & social care | 2008 |
| Energygroup Consulting Ltd | Wholesale & retail | 2023 |
| Energylogik Ltd | Professional & scientific | 2021 |
| Enfield Norse Limited | Other services | 2009 |
| Engage Media Ltd | Professional & scientific | 2023 |
| Engage Personnel Ltd | Administrative & support | 2019 |
| Engage Visually Ltd | Professional & scientific | 2012 |
| Engage With Business Limited | Administrative & support | 2006 |
| Engineering Magic Ltd | Professional & scientific | 2024 |
| Engineering Projects Integration Consultants Limited | Construction | 2014 |
| Engineering Skill SET Ltd | Professional & scientific | 2024 |
| English @ ICS Limited | Education | 2003 |
| English Hymnal Company Limited(The) | Information & communication | 1926 |
| English Voice Real Estate Limited | Real estate | 2007 |
| English Whisky Co. Limited | Manufacturing | 1981 |
| Engram Ltd | Information & communication | 2013 |
| Enhanced Construction Ltd | Construction | 2017 |
| Enhanced Healthcare Services Ltd | Health & social care | 2014 |
| Enhanced Resource Ltd | Administrative & support | 2014 |
| Enicha Ltd | Construction | 2014 |
| Enigma Estates Limited | Real estate | 2016 |
| Enigma Innovation and Development Ltd | Professional & scientific | 2021 |
| Enixus Apparel UK Ltd | Wholesale & retail | 2006 |
| Enjoy Burger Ltd | Wholesale & retail | 2026 |
| Enjoyeat Ltd | Wholesale & retail | 2024 |
| Enjoys Pizza Ltd | Hospitality | 2019 |
| ENK Limited | Professional & scientific | 2000 |
| ENK Nominee Ltd | Professional & scientific | 2014 |
| Enkel Consulting Ltd | Professional & scientific | 2023 |
| Enlight Technologies Limited | Professional & scientific | 2003 |
| ENM Services Ltd | Water & waste | 2019 |
| ENMASSE2 Limited | Professional & scientific | 2022 |
| Enoch Fuels UK Ltd | Wholesale & retail | 2014 |
| Enodirect UK Limited | Wholesale & retail | 2011 |
| Enquirer Media Group Limited | Information & communication | 2025 |
| Enrich Learning Trust | Education | 2011 |
| Enriched Homes Limited | Real estate | 2022 |
| ENRIQUE21 Limited | Hospitality | 2022 |
| Enriquez Mate Ltd | Wholesale & retail | 2025 |
| Ensco 827 Limited | Households | 2010 |
| Ensley Starlight Property Ltd | Real estate | 2021 |
| Enstrat(Uk) Ltd | Professional & scientific | 2014 |
| ENT and Hearing Healthcare Limited | Health & social care | 2019 |
| ENT Norwich Ltd | Health & social care | 2014 |
| Entada Gigas Ltd | Health & social care | 2023 |
| Enter the Void Limited | Professional & scientific | 2012 |
| Enterprise Agility Limited | Professional & scientific | 2020 |
| Enterprise Digital Services Ltd | Information & communication | 2024 |
| Enterprise Innovation Holdings Limited | Financial services | 2023 |
| Enterprise Private Hire Limited | Transport & logistics | 2003 |
| Entertainment Rescue Limited | Arts & recreation | 2011 |
| Entire Personnel Solutions Limited | Administrative & support | 2012 |
| ENTITY3 Limited | Information & communication | 2015 |
| Entrepreneur Education Limited | Education | 2010 |
| Enviity Ltd | Professional & scientific | 2024 |
| Enviro-Heat Ltd | Wholesale & retail | 2017 |
| Enviro-Pod Limited | Manufacturing | 1999 |
| Envirofacilities UK Limited | Administrative & support | 2021 |
| Enviromate Limited | Manufacturing | 2011 |
| Enviromax Soil Solutions Limited | Professional & scientific | 2024 |
| Environment Innovations Ltd | Professional & scientific | 2024 |
| Environmental Sustainability Associates Limited | Professional & scientific | 2014 |
| Enviroq Design Solutions Ltd | Construction | 2024 |
| Envisage Home Ltd | Wholesale & retail | 2017 |
| Envision Engineering Ltd | Professional & scientific | 2024 |
| Envisioncad Ltd | Administrative & support | 2017 |
| Envs Home Limited | Professional & scientific | 2025 |
| Envy London Limited | Wholesale & retail | 2016 |
| Enzl Limited | Information & communication | 2006 |
| Enzo Engineering Ltd | Professional & scientific | 2021 |
| EO Infraco 1 LEN Limited | Transport & logistics | 2024 |
| EOB Electrical and Inspection Ltd | Construction | 2024 |
| EOC Enterprises Ltd | Arts & recreation | 1994 |
| EOC SPV Limited | Education | 2014 |
| EOE Catering Ltd | Hospitality | 2025 |
| EOL Trading Ltd | Wholesale & retail | 2012 |
| EP Catering Limited | Hospitality | 2022 |
| EP IT Solutions Ltd | Information & communication | 2026 |
| EP Photography & Videography Services Ltd | Information & communication | 2022 |
| EP Property Management (Norfolk) Ltd | Real estate | 2022 |
| Ep&H Properties Ltd | Real estate | 2025 |
| EPA Property Services Ltd | Construction | 2024 |
| EPC Aerospace UK Limited | Manufacturing | 2024 |
| EPC Norfolk Ltd | Professional & scientific | 2015 |
| Epcl Ltd | Hospitality | 2018 |
| Epem Limited | Administrative & support | 1983 |
| Epic EV Studios Limited | Information & communication | 2025 |
| Epicure Digital Marketing Ltd | Administrative & support | 2015 |
| Epicurean Hospitality Services Ltd | Hospitality | 2025 |
| EPM Apps Consulting Ltd | Information & communication | 2013 |
| Eponymous Holdings Ltd | Wholesale & retail | 2015 |