| Stuart Covers Limited | Administrative & support | 2003 |
| Studio 43 Brows Ltd | Other services | 2021 |
| Style Creative Products Limited | Wholesale & retail | 2002 |
| Submitfox Ltd | Administrative & support | 2025 |
| SUE Tindall & Associates Limited | Professional & scientific | 2004 |
| Sugar Road Developments Limited | Real estate | 2022 |
| Sultan Kebab House Ltd | Hospitality | 2025 |
| Sun LUX Lounge Ltd | Other services | 2023 |
| Sunho Limited | Hospitality | 2011 |
| Sunley Aviation Ltd | Transport & logistics | 2026 |
| Sunny BBQ Ltd | Hospitality | 2017 |
| Sunny Days Consulting Ltd | Administrative & support | 2026 |
| Sunny Sky Investment Ltd | Real estate | 2020 |
| Sunset Travel (Northwich) Limited | Transport & logistics | 2002 |
| Super North Star Limited | Professional & scientific | 2020 |
| Super Value Tech Limited | Wholesale & retail | 2025 |
| Superbox (Northwich) C.I.C. | Education | 2021 |
| Superellipse Consultancy Services Limited | Professional & scientific | 2025 |
| Superyest Ltd | Education | 2018 |
| Supplestack Ltd | Wholesale & retail | 2025 |
| Supplied Agency Ltd | Wholesale & retail | 2024 |
| Supply Side Focus Ltd | Professional & scientific | 2002 |
| Supreme Development Manchester Ltd | Construction | 2020 |
| Sure Developments Limited | Construction | 2026 |
| Sure Move Part Exchange and Estate Agency Limited | Real estate | 2025 |
| Sure Park Limited | Hospitality | 1998 |
| Surgix Ltd | Health & social care | 2007 |
| Survikaa Limited | Health & social care | 2015 |
| Susan Gilby Limited | Professional & scientific | 2023 |
| Susan Howarth & Co Solicitors Ltd | Professional & scientific | 2012 |
| Sustainable Gift Boxes UK Ltd | Wholesale & retail | 2023 |
| Sutcliffe Torrance Real Estate Ltd | Extraterritorial | 2022 |
| Swag and WAG Ltd | Wholesale & retail | 2014 |
| Sweet Water Holdings (Cheshire) Ltd | Health & social care | 2026 |
| SWN Consultancy Ltd | Information & communication | 2020 |
| Sworn Performance Ltd | Wholesale & retail | 2026 |
| SYB Consulting Limited | Professional & scientific | 2021 |
| Sycamore & Jervis Holdings Limited | Financial services | 2022 |
| Symmetros Consulting Limited | Professional & scientific | 2025 |
| Synapse Dynamic Ltd | Information & communication | 2025 |
| Synapse Electric & AV Ltd | Construction | 2026 |
| Synchroprint Ltd | Manufacturing | 2010 |
| Syncrasoft Ltd | Information & communication | 2024 |
| Synergy Automation Limited | Information & communication | 2013 |
| Synergy Consultancy Services Ltd | Information & communication | 2007 |
| Synthesis Recruitment Ltd | Professional & scientific | 2021 |
| Szark Limited | Transport & logistics | 2024 |
| T Natural Care (UK) Limited | Wholesale & retail | 2026 |
| T Venables Track Works Limited | Construction | 2016 |
| T&A Wash Ltd | Administrative & support | 2024 |
| T.T.R Productions Ltd | Arts & recreation | 2024 |
| T.V. Developments Limited | Construction | 2019 |
| T.W. Crofts Limited | Professional & scientific | 2021 |
| T2SERVICES UK Limited | Extraterritorial | 2014 |
| T9 Data Ltd | Professional & scientific | 2016 |
| Take 2 Couriers Limited | Other services | 2007 |
| Tala Equity Limited | Professional & scientific | 2010 |
| Talkinvest Limited | Financial services | 2017 |
| Tall Trees Farm Limited | Manufacturing | 2014 |
| Tambour Doors Limited | Wholesale & retail | 2001 |
| Tamias Global Ltd | Wholesale & retail | 2023 |
| Tamias UK Ltd | Wholesale & retail | 2023 |
| Tango Down Airsoft Ltd | Wholesale & retail | 2017 |
| Tansley Services Ltd | Professional & scientific | 2026 |
| Tarcroft Ltd | Professional & scientific | 2017 |
| Target Composites Limited | Manufacturing | 2015 |
| Target Trade 1 Ltd | Wholesale & retail | 2024 |
| Tarran Innovation Limited | Professional & scientific | 2025 |
| Tarranbrae Annexe Management Ltd | Households | 2017 |
| Tasty Kitchen Express Limited | Hospitality | 2019 |
| Tata Chemicals Europe Limited | Manufacturing | 1991 |
| Tata Chemicals Magadi Limited | Manufacturing | 1924 |
| Tato Holdings Limited | Financial services | 1996 |
| Tatton Fencing Ltd | Construction | 2017 |
| Tatton Horseboxes Limited | Manufacturing | 2012 |
| Tawakkul Northwich Limited | Hospitality | 2025 |
| Taylor Contracting (NW) Limited | Agriculture & fishing | 2021 |
| Taylor Made Environmental Solutions Ltd | Professional & scientific | 2017 |
| Taylor Wilkinson Leisure Limited | Hospitality | 2021 |
| Taylor Wilkinson Surveyors Limited | Administrative & support | 2014 |
| Taylor, Naylor & Ogden Ltd | Hospitality | 2019 |
| Taylors Property Management Ltd | Households | 2025 |
| Taylory Ltd | Professional & scientific | 2008 |
| TB Electrics and Home Improvements Limited | Construction | 2006 |
| TBS Building Surgery Ltd | Construction | 2024 |
| TC Africa Holdings Limited | Professional & scientific | 1991 |
| Tcam Solutions Ltd | Professional & scientific | 2024 |
| TCE Group Limited | Financial services | 2010 |
| TD Freight-Pro Limited | Wholesale & retail | 2011 |
| TD4 Milkshakes Limited | Wholesale & retail | 2015 |
| TDJ International Limited | Professional & scientific | 2024 |
| TDM Stores Ltd | Information & communication | 2024 |
| TE Consulting Limited | Financial services | 2016 |
| Teacher Absence Limited | Financial services | 2013 |
| Teacher Absence Limited Partnership | | 2018 |
| Tecalliance Limited | Information & communication | 2001 |
| Tech Goro Limited | Wholesale & retail | 2025 |
| Techflow Drainage Ltd | Construction | 2013 |
| Techrad Limited | Administrative & support | 2015 |
| Techwow Ltd | Wholesale & retail | 2022 |