| Equitech Group Limited | Information & communication | 2023 |
| Equizapper Ltd | Manufacturing | 2025 |
| ERA Sound Ltd | Information & communication | 2022 |
| ERB Property Management Ltd | Real estate | 2022 |
| Erco Cosmetics Ltd | Other services | 2021 |
| Erco Solutions Limited | Public administration | 2020 |
| ERE Property Group Ltd | Real estate | 2024 |
| Eretailcottage Limited | Wholesale & retail | 2021 |
| Ergo Bibamus Ltd | Wholesale & retail | 2007 |
| Ergonomic Design Limited | Wholesale & retail | 2007 |
| Erika Consulting Limited | Professional & scientific | 2013 |
| Erin's Apron Ltd | Hospitality | 2026 |
| Eris Inc. Ltd. | Information & communication | 2025 |
| Erisoft Ltd | Information & communication | 2014 |
| Erlander Real Estate Limited | Real estate | 2019 |
| Ernc Consultancy Ltd | Professional & scientific | 2025 |
| Ernie Transport Limited | Transport & logistics | 2025 |
| ERP Development Ltd | Professional & scientific | 2023 |
| Errigal Utilities Ltd | Construction | 2013 |
| Erroll Emmanuel Chambers Ltd | Extraterritorial | 2025 |
| ERS Group Limited | Manufacturing | 1976 |
| Ersi 12 Ltd | Transport & logistics | 2023 |
| Erva Cafe Ltd | Hospitality | 2023 |
| Ervi Property Investment Ltd | Real estate | 2026 |
| ES Electrical (Midlands) Ltd | Construction | 2018 |
| ES Group Holdings (Midlands) Limited | Financial services | 2024 |
| ES Properties (Midlands) Limited | Real estate | 2024 |
| ES Roofing Northampton Ltd | Construction | 2024 |
| ESA Auto Design Limited | Wholesale & retail | 2021 |
| Esazen Ltd | Professional & scientific | 2021 |
| Escapade PR & Marketing Limited | Professional & scientific | 2017 |
| Escape Venue Ltd | Hospitality | 2019 |
| Esdo P&P Ltd | Wholesale & retail | 2025 |
| Eshelby Holdings Limited | Professional & scientific | 2013 |
| Eska Ltd | Real estate | 2017 |
| ESM Northampton Ltd | Wholesale & retail | 2024 |
| Esmaj Blessed Hands Cleaning Services Ltd | Administrative & support | 2026 |
| Esme Ltd | Other services | 2020 |
| Esolutionsonline Limited | Information & communication | 2013 |
| Esoteric Solutions Limited | Professional & scientific | 2018 |
| Esotrc Ltd | Wholesale & retail | 2024 |
| Esperanza Healthcare and Beauty Limited | Health & social care | 2025 |
| Esperer Care Limited | Health & social care | 2020 |
| Espi Properties Ltd | Real estate | 2017 |
| Esquared Clothing Limited | Wholesale & retail | 2021 |
| Essay Associates Ltd | Wholesale & retail | 2004 |
| Essence Analytics Limited | Information & communication | 2017 |
| Essence Occupational Therapy Limited | Health & social care | 2019 |
| Essential Central Limited | Manufacturing | 2023 |
| Essenzio Ltd | Wholesale & retail | 2025 |
| Essex Batteries Limited | Manufacturing | 2013 |
| Essex E-Liquid Ltd | Wholesale & retail | 2015 |
| Essex Finishers Ltd | Manufacturing | 2015 |
| Essex Neurosurgical Services Limited | Health & social care | 2018 |
| Essex Skin Limited | Health & social care | 2022 |
| Essex Swifts Basketball Club Limited | Arts & recreation | 1996 |
| Essjay Consulting Ltd | Professional & scientific | 2019 |
| Esteiro Business Solutions Limited | Information & communication | 2001 |
| Esteiro Holdings Limited | Information & communication | 2011 |
| Estelle Healthcare Limited | Health & social care | 2023 |
| Estha Jones School of Dance Limited | Education | 2010 |
| Esther Healthcare Limited | Health & social care | 2022 |
| Esthtrans Ltd | Transport & logistics | 2023 |
| Estia London Ltd | Construction | 2022 |
| Estilo Shop Ltd | Wholesale & retail | 2019 |
| Estol Works Limited | Hospitality | 2023 |
| Esuru Co Limited | Wholesale & retail | 2019 |
| ET Building Limited | Construction | 2016 |
| ET Oldco Limited | Wholesale & retail | 2004 |
| ET Salutem Ltd | Professional & scientific | 2022 |
| Etalon Brick & Stone Ltd | Construction | 2020 |
| Etch & Bond Limited | Health & social care | 2022 |
| Etch Your Dreams Limited | Manufacturing | 2025 |
| Etched Empire Limited | Professional & scientific | 2026 |
| Etchflare Limited | Administrative & support | 2022 |
| Etechod Limited | Information & communication | 2024 |
| Eternia Ltd | Arts & recreation | 2021 |
| Eternity Apparel UK Limited | Wholesale & retail | 2023 |
| Eternum Ltd | Information & communication | 2009 |
| Eteski Ltd | Real estate | 2015 |
| Ethica Leather Limited | Extraterritorial | 2016 |
| Ethical Edge Consulting Ltd | Professional & scientific | 2023 |
| Ethicall Field Services Ltd | Financial services | 2009 |
| Ethikks Ltd | Wholesale & retail | 2026 |
| ETI Electrical Ltd | Construction | 2022 |
| ETI KET Social CIC | Public administration | 2023 |
| Etias Payroll Services Ltd | Professional & scientific | 2025 |
| Etico Group Limited | Financial services | 2006 |
| Etinde House Company Ltd. | Manufacturing | 2019 |
| Etiquette Limited | Real estate | 2020 |
| Etiquette Services Limited | Administrative & support | 2003 |
| Etisec Limited | Administrative & support | 2017 |
| Etiti Global Limited | Administrative & support | 2025 |
| ETM Cars Ltd | Transport & logistics | 2024 |
| Eton Court (Kingsthorpe) Residents Association Limited | Households | 1988 |
| Eton Property Group Ltd | Real estate | 2016 |
| Etone Place (Nuneaton) Residents Management Company Limited | Households | 2007 |
| ETR Sport Ltd | Arts & recreation | 2025 |
| ETS Property Services CIC | Real estate | 2023 |
| ETS Vilatte Ltd | Information & communication | 2025 |