| Enchanted Furnishings Limited | Wholesale & retail | 2017 |
| Enchanted Kitchen Revival Ltd. | Wholesale & retail | 2015 |
| Enclave Studios Limited | Extraterritorial | 2018 |
| Encon Maintain Ltd | Manufacturing | 2011 |
| END Climate Change Limited | Financial services | 2020 |
| END of the Line Stock Ltd | Wholesale & retail | 2021 |
| END Point Assess Ltd | Administrative & support | 2020 |
| Endeavour Construction Limited | Construction | 2005 |
| Endeavour Property & Garden Maintenance Ltd | Construction | 2021 |
| Endera Group Ltd | Wholesale & retail | 2024 |
| Endless Engineering Aerospace Limited | Manufacturing | 2025 |
| Endless Transport Limited | Transport & logistics | 2022 |
| Endshpil Ltd | Wholesale & retail | 2022 |
| Endurosport LLP | | 2021 |
| Enerfac Services Limited | Extraterritorial | 2011 |
| Energise Enterprises Ltd | Information & communication | 2010 |
| Energy Electrical Contracting Limited | Construction | 2008 |
| Energy Engine Ltd | Information & communication | 2014 |
| Energy Partners Solutions Ltd | Construction | 2020 |
| Energyexchangers Limited | Construction | 2008 |
| Enfes Limited | Hospitality | 2016 |
| Enfield's Avionics Support & Engineering Ltd | Transport & logistics | 2015 |
| Enforcement App Ltd | Administrative & support | 2025 |
| Enframe CIC | Energy | 2018 |
| Engage Umbrella Limited | Administrative & support | 2023 |
| Engaged People Limited | Other services | 2015 |
| Engine Mapper Ltd | Manufacturing | 2025 |
| Engineered Foam Products Limited | Manufacturing | 2018 |
| Engineering Entropy Ltd | Other services | 2018 |
| Engineering Milestone Management Limited | Professional & scientific | 2026 |
| Engineering Precision Solutions Limited | Manufacturing | 2014 |
| Engineering Project Solutions Ltd | Professional & scientific | 2019 |
| Engineering Technologies & Manufacturing Limited | Manufacturing | 1998 |
| Enhance Automotive Ltd | Other services | 2025 |
| Enhance Construction & Development Limited | Construction | 2016 |
| ENI Engineering Consulting Ltd | Transport & logistics | 2018 |
| ENI GEE Limited | Construction | 2025 |
| Enil Limited | Construction | 2006 |
| Enimon Limited | Information & communication | 2025 |
| Enitan Holdings Ltd | Hospitality | 2018 |
| Enixcare Limited | Health & social care | 2018 |
| Enjector Software Limited | Information & communication | 2003 |
| Enjoy Construction Ltd | Construction | 2022 |
| Enjoy Creative Ltd | Professional & scientific | 2023 |
| Enlightened Leadership Limited | Professional & scientific | 2013 |
| Enlighters Ltd | Hospitality | 2011 |
| Enmase Ltd | Administrative & support | 2025 |
| Ennd Barbershop Ltd | Other services | 2024 |
| Enpad - European Network of People of African Descent | Other services | 2017 |
| Enrich Beauty Limited | Other services | 2022 |
| Enroute Taxis Ltd | Transport & logistics | 2020 |
| ENT Medical Care Ltd | Health & social care | 2025 |
| Entech Systems Ltd | Information & communication | 2024 |
| Enterprise Analysis Limited | Information & communication | 2007 |
| Enterprise Sourcing Ltd | Wholesale & retail | 2023 |
| Enterprisingh Solutions Limited | Information & communication | 2022 |
| Entheogen Consulting Limited | Professional & scientific | 2025 |
| Enurgent Renewables Ltd | Wholesale & retail | 2026 |
| Env-Uk Limited | Professional & scientific | 2013 |
| Enviro Clean Milton Keynes Ltd | Administrative & support | 2026 |
| Enviro Heating & Cooling Ltd | Construction | 2020 |
| Enviro-Serve Limited | Transport & logistics | 2003 |
| Environ Civil Engineering Limited | Construction | 2014 |
| Environment Ecology Ltd | Water & waste | 2025 |
| Environment Friendly Tyres Ltd | Wholesale & retail | 2020 |
| Environmental Remediation (UK) Limited | Professional & scientific | 2007 |
| Enviroserve Facilities Support Limited | Administrative & support | 2020 |
| Envirotechnology Limited | Professional & scientific | 2023 |
| Enviroval Limited | Extraterritorial | 2001 |
| Envisage Carpentry Ltd | Manufacturing | 2019 |
| Envisionary Ltd | Information & communication | 2021 |
| Envoy Finance Limited | Real estate | 2022 |
| Envoy Real Estate Ltd | Real estate | 2025 |
| Enyx Solutions Ltd | Professional & scientific | 2015 |
| EOB Productions Ltd | Information & communication | 2026 |
| EOS Property Ltd | Real estate | 2023 |
| EP Data Services Limited | Information & communication | 2017 |
| EPC Buildings Limited | Construction | 2018 |
| EPH Services Ltd | Construction | 2017 |
| Eph-Stop Lighting Ltd | Information & communication | 2016 |
| Ephgrave Lighting Limited | Construction | 2012 |
| Epi-No UK Ltd | Health & social care | 2015 |
| Epic Pool and Construction Ltd | Construction | 2021 |
| Epic Sports & Hospitality Ltd | Administrative & support | 2024 |
| Epicurean Essence Ltd | Hospitality | 2024 |
| EPN Communications Ltd | Professional & scientific | 2010 |
| Epos Care Ltd | Health & social care | 2019 |
| Epping High Street Limited | Construction | 2015 |
| Epps Performance Ltd | Arts & recreation | 2026 |
| Epropertysolutions Ltd | Real estate | 2014 |
| EPS Trenchless Installations Ltd | Construction | 2011 |
| Epsilon ADS Limited | Professional & scientific | 2025 |
| Epsom Court Residents Management Company Limited | Households | 1971 |
| Eqate Limited | Financial services | 2006 |
| Eqmp Ltd | Professional & scientific | 2024 |
| Equestriman Limited | Wholesale & retail | 2014 |
| Equilibrion Limited | Professional & scientific | 2022 |
| Equipped Architectural & Engineering Solutions Ltd. | Construction | 2016 |
| Equitas Global Limited | Professional & scientific | 2025 |
| Equitech Electrical Solutions Limited | Construction | 2022 |