| Deep Blue Sky Consultants Ltd | Professional & scientific | 2024 |
| Deep Red Creative Limited | Wholesale & retail | 2010 |
| Deeper Being LLP | | 2017 |
| Deepland Studios Limited | Information & communication | 2024 |
| Deevine Healthcare Ltd | Health & social care | 2022 |
| Deezi Management Limited | Arts & recreation | 2007 |
| Defender UK Consultants Limited | Information & communication | 2013 |
| Defined Space Limited | Wholesale & retail | 2023 |
| Definitive Housekeeping Group (DHG) Ltd | Administrative & support | 2023 |
| Defy by Isla Ltd | Other services | 2022 |
| Defy by Isla Retail Ltd | Wholesale & retail | 2024 |
| Degrace Supported Living Ltd | Health & social care | 2025 |
| Deice Limited | Health & social care | 2024 |
| Deivisbuild Limited | Construction | 2014 |
| Deja VU Restaurant Ltd | Hospitality | 2023 |
| Dekel Limited | Hospitality | 2019 |
| Dekey Technologies UK Limited | Information & communication | 2018 |
| Delamain-Blunt Limited | Professional & scientific | 2007 |
| Delange Design Limited | Professional & scientific | 2011 |
| Delaporte Enterprises Ltd | Financial services | 2017 |
| Delapre Abbey Enterprises Limited | Hospitality | 2016 |
| Delapre Abbey Preservation Trust | Arts & recreation | 2006 |
| Delapre Court (Management) Limited | Households | 1985 |
| Delapre Golf Centre Limited | Arts & recreation | 2003 |
| Delapre Real Estate Limited | Real estate | 2021 |
| Delapre Roofing Ltd | Construction | 2019 |
| Delasole Group Ltd | Other services | 2025 |
| Delato Finance Ltd | Financial services | 2024 |
| Delcons Northampton Limited | Construction | 2016 |
| Deldun Services Ltd | Construction | 2021 |
| Delf Mews Limited | Households | 2016 |
| Delf Mews Management Ltd | Households | 2020 |
| Delicious Northampton Ltd | Hospitality | 2017 |
| Delicious Pizza & Kebab Ltd | Hospitality | 2025 |
| Delight Northampton Ltd | Hospitality | 2024 |
| Delight Physiotherapy Limited | Health & social care | 2026 |
| Deliorman Ltd | Hospitality | 2019 |
| Delivery Specialist Ltd | Transport & logistics | 2026 |
| Delivux Logistics Ltd | Transport & logistics | 2024 |
| Delizia ITA Ltd | Hospitality | 2024 |
| Delkii Group Ltd | Construction | 2022 |
| Delkim Developments Limited | Professional & scientific | 2001 |
| Delkim Limited | Manufacturing | 1991 |
| Delkim Products Limited | Manufacturing | 1985 |
| Dellavita Ltd | Wholesale & retail | 2025 |
| Delnet Limited | Professional & scientific | 2004 |
| Delta Actuarial Services Ltd | Professional & scientific | 2018 |
| Delta Consultants Services Limited | Administrative & support | 2017 |
| Delta Cosworth Limited | Administrative & support | 2005 |
| Delta Demolition Limited | Construction | 2001 |
| Delta Ecowild Safaris (PTY) Ltd | Administrative & support | 2026 |
| Delta Nursing Agency Ltd | Administrative & support | 1998 |
| Delta OIL Ltd | Manufacturing | 2016 |
| Deltaneutral Limited | Arts & recreation | 2022 |
| Delteva Ltd | Manufacturing | 2019 |
| Deltin Ltd | Administrative & support | 2017 |
| Deltrans Limited | Wholesale & retail | 2004 |
| Deluxe Developers Limited | Construction | 2012 |
| Deluxe Windows Ltd | Construction | 2020 |
| Deluxurie Ltd | Real estate | 2023 |
| Delvitae Ltd | Wholesale & retail | 2022 |
| Delz Couriers Ltd | Transport & logistics | 2025 |
| Demand Flow Analytics Limited | Information & communication | 2024 |
| Demarie Ltd | Professional & scientific | 2014 |
| Demayol International Limited | Professional & scientific | 2016 |
| Demidav Ltd | Health & social care | 2018 |
| Demo Properties (Broad Haven) Limited | Real estate | 2020 |
| Demograffix Publishing Services Limited | Hospitality | 1995 |
| Demorti Ltd | Real estate | 2026 |
| Denby Camphill C.I.C. | Health & social care | 2026 |
| Dendale Limited | Construction | 1975 |
| Denim Consulting Limited | Professional & scientific | 2025 |
| Deniroes Heating Limited | Construction | 2017 |
| Denis Nicolae Ltd | Transport & logistics | 2020 |
| Deniss Solutions Ltd | Energy | 2026 |
| Dennis Gifts Ltd | Manufacturing | 2021 |
| Dent and Prefect Holdings Limited | Financial services | 2025 |
| Dentacruit Services Ltd | Health & social care | 2015 |
| Dental Partners (Disa) Limited | Health & social care | 2007 |
| Dental Partners Bidco Limited | Health & social care | 2016 |
| Dental Partners Conisbrough Limited | Health & social care | 2019 |
| Dental Partners Finco Limited | Health & social care | 2016 |
| Dental Partners Group Limited | Health & social care | 2016 |
| Dental Partners Holdings Limited | Health & social care | 2009 |
| Dental Partners Kiveton Limited | Health & social care | 2019 |
| Dental Partners Midco Limited | Health & social care | 2016 |
| Dental Partners Morley Limited | Health & social care | 2019 |
| Dental Partners Trading Limited | Health & social care | 2017 |
| Dental Sense Limited | Health & social care | 2007 |
| Dentapol Limited | Health & social care | 2006 |
| Denticheck Limited | Health & social care | 2006 |
| Denton Blinds Limited | Wholesale & retail | 2005 |
| Denton Legacy Limited | Financial services | 2025 |
| Denu Services Ltd | Health & social care | 2018 |
| Denwer Ltd | Professional & scientific | 2021 |
| Denymar Trans Ltd | Transport & logistics | 2024 |
| Denys Transportation Ltd | Transport & logistics | 2025 |
| Deprop Limited | Real estate | 2016 |
| Dept 68 Limited | Hospitality | 2025 |
| Derac Ltd | Transport & logistics | 2024 |