| Crispymill Inns Ltd | Hospitality | 2022 |
| Crosby Farming Ltd | Agriculture & fishing | 2026 |
| Cross Property Solutions Ltd | Real estate | 2021 |
| Crossfield Homes Limited | Construction | 2013 |
| Crow Leisure Group Ltd | Administrative & support | 2021 |
| Crow Live Limited | Financial services | 2024 |
| Crows Events & Attractions Ltd | Arts & recreation | 2020 |
| CS Worldwide Ltd | Information & communication | 2017 |
| CSY 2020 Ltd | Professional & scientific | 2020 |
| CUC Solutions Limited | Wholesale & retail | 2014 |
| Cultivate Success Ltd | Professional & scientific | 2023 |
| Customised Cleaning Ltd | Administrative & support | 2025 |
| CW Property Rentals Ltd | Real estate | 2025 |
| D & a Chapman Glamping Limited | Hospitality | 2026 |
| D & R Chappell Ltd | Manufacturing | 2021 |
| D Bellamy Brickwork Ltd | Construction | 2022 |
| D E B Town Planning and Development Ltd | Professional & scientific | 2013 |
| D J Peary Limited | Professional & scientific | 2022 |
| D Mcmahon Sandwich Bars Limited | Hospitality | 2020 |
| D.L. & P.R. Prest Limited | Agriculture & fishing | 1991 |
| D2 Estates Ltd | Real estate | 2024 |
| DAB Golf Ltd | Arts & recreation | 2022 |
| Daikon GC Ltd | Hospitality | 2024 |
| Dales Academies Trust | Education | 2013 |
| Danny Cameron Limited | Professional & scientific | 2013 |
| DAP Motor Services Limited | Wholesale & retail | 2011 |
| Data Stream UK Services Limited | Information & communication | 2023 |
| Davecarterjoinery Ltd | Construction | 2012 |
| Davis Pondscapes Ltd | Administrative & support | 2023 |
| Davis Ventures Limited | Administrative & support | 2026 |
| Dawes London Ltd | Real estate | 2021 |
| Dawson Farms Limited | Agriculture & fishing | 2004 |
| DB Hire Centre Northallerton Ltd | Administrative & support | 2025 |
| DC Designs Limited | Administrative & support | 1999 |
| DC Joinery NE Ltd | Construction | 2025 |
| DC Vehicle Services Ltd | Transport & logistics | 2026 |
| DCM Recruitment Ltd | Education | 2022 |
| DCX Property Group Limited | Real estate | 2018 |
| Dean.Juniper Ltd | Construction | 2026 |
| Deansbury Kitchens Ltd | Manufacturing | 2003 |
| Deere Street Farm Ltd | Agriculture & fishing | 2022 |
| DH Project Management Services Ltd | Professional & scientific | 2022 |
| Diamond Hands Property Ltd | Real estate | 2022 |
| Dick Garner & Sons Limited | Real estate | 1943 |
| Dick Lawson Limited | Real estate | 1968 |
| Dick Lawson Yorkshire Limited | Real estate | 2014 |
| Digital Blonde Ltd | Professional & scientific | 2011 |
| Dinky Drawings Limited | Professional & scientific | 2024 |
| Dinsdale Consulting Ltd | Professional & scientific | 2021 |
| Divinely Guided Ltd | Health & social care | 2026 |
| Dixon & Cowton Cabinet Makers Limited | Manufacturing | 2015 |
| DJH Consultancy Services Ltd. | Professional & scientific | 2016 |
| DMH Hydraulics Ltd | Professional & scientific | 2013 |
| DNS Properties Management Limited | Real estate | 2026 |
| Dobsons Coaches (Bedale) Limited | Transport & logistics | 2006 |
| Doch AI Limited | Information & communication | 2026 |
| Dodgson Holdings Ltd | Real estate | 2021 |
| Dolly Lane Lodges Limited | Hospitality | 2023 |
| Dominic Simpson Finance Limited | Financial services | 2025 |
| Donald PIG & Poultry Ltd | Agriculture & fishing | 2012 |
| Donlen Medical Ltd. | Health & social care | 2018 |
| Doodleaviation Limited | Professional & scientific | 2022 |
| DR1 Aerial Ltd | Professional & scientific | 2021 |
| Draft Structural Detailing Ltd | Professional & scientific | 2008 |
| Dramatic Scope Ltd | Health & social care | 2022 |
| Drapable Limited | Wholesale & retail | 2021 |
| DRC Consultants Limited | Health & social care | 2025 |
| Drew & Co UK Ltd | Administrative & support | 2024 |
| DS Trading Car and Commercial Vehicle Sales Ltd | Wholesale & retail | 2022 |
| Duoserve Ltd | Construction | 2020 |
| DW Courtyard Rooms Welbury Ltd | Hospitality | 2024 |
| Dyno Centre Ltd | Wholesale & retail | 2014 |
| East Appleton Farm Limited | Agriculture & fishing | 2014 |
| East Cawthorne Farming | Agriculture & fishing | 2012 |
| East Cowton Properties Limited | Real estate | 2014 |
| Ebor Compliance Ltd | Administrative & support | 2024 |
| Ebor Education Ltd. | Education | 2014 |
| EC Attractions Limited | Arts & recreation | 2016 |
| EC Events Group Ltd | Arts & recreation | 2021 |
| Eieio Holdings Limited | Construction | 2014 |
| EIS Consulting Limited | Professional & scientific | 2013 |
| EJS Plant Ltd | Wholesale & retail | 2015 |
| Elders Limited | Extraterritorial | 2003 |
| Eldmire Farming Limited | Agriculture & fishing | 2010 |
| Electric Orange Event Services Limited | Professional & scientific | 2003 |
| Electrocare (Northallerton) Ltd | Manufacturing | 2011 |
| Ella Blue Ltd | Wholesale & retail | 2025 |
| ELM Tree Agricultural Limited | Agriculture & fishing | 2017 |
| Elmcote Design Limited | Information & communication | 2005 |
| Elstob Medical Limited | Health & social care | 2012 |
| Eltel-Uk. Limited | Construction | 2009 |
| EM1 Ltd | Construction | 2016 |
| EMHARR267 Ltd | Hospitality | 2025 |
| Emilia and Zybi Property Ltd | Real estate | 2025 |
| Emma Brown Interiors Ltd | Professional & scientific | 2023 |
| Emma Kerfoot's Ladybirds Limited | Education | 2017 |
| Endican Consulting Ltd | Professional & scientific | 2025 |
| Energi North East Ltd | Administrative & support | 2016 |
| Engine Services Ltd | Manufacturing | 2024 |
| English Language Training Ltd | Education | 2014 |