| Quantenv Consulting Ltd | Professional & scientific | 2026 |
| Quantum Accounting and Business Solutions Ltd | Professional & scientific | 2024 |
| Quay (N.E.) Leisure Limited | Real estate | 1995 |
| Quay 3 Facility Management Limited | Administrative & support | 2015 |
| Quay Bakehouse Limited | Manufacturing | 2025 |
| Quay Cassia Ltd | Hospitality | 2019 |
| Quay Joinery Limited | Construction | 2004 |
| Quayside Images Ltd | Professional & scientific | 2015 |
| Quora Group Ltd | Construction | 2005 |
| Quora Group Service Ltd | Construction | 2019 |
| R - Clean Limited | Administrative & support | 2019 |
| R Diddee Limited | Health & social care | 2019 |
| R Duffield Property Trading Limited | Real estate | 2017 |
| R Duffield Rentals Limited | Real estate | 2023 |
| R W Graham Engineering Ltd | Manufacturing | 2025 |
| R&D Bidding Platform Limited | Real estate | 2025 |
| R&D Demolition UK Ltd | Water & waste | 2016 |
| R&R Waste and Removals Ltd | Water & waste | 2023 |
| R.D. Flooring Limited | Wholesale & retail | 2011 |
| R.Jnr Property Ltd | Real estate | 2025 |
| RA CAB Services Limited | Transport & logistics | 2024 |
| Rach Bakes Ltd | Manufacturing | 2017 |
| Radar Taxis Limited | Transport & logistics | 2014 |
| Rahip Limited | Other services | 2018 |
| Ramsey Consultancy Limited | Professional & scientific | 2026 |
| Random Walk Limited | Professional & scientific | 2007 |
| Rare Flooring Ltd | Wholesale & retail | 2019 |
| Rare Innovations Ltd | Professional & scientific | 2017 |
| Rascals Playtime Childcare Limited | Education | 2015 |
| Rasmussen Engineering Limited | Professional & scientific | 2018 |
| Rawson Studios Ltd | Information & communication | 2025 |
| Rayfire Services Limited | Public administration | 2020 |
| RAZAQ95 Ltd | Professional & scientific | 2019 |
| Razorbill Blue Ltd | Information & communication | 2024 |
| Razzberry Bazaar Ltd | Wholesale & retail | 2017 |
| Razzle Jazzel Leisure Ltd | Hospitality | 2017 |
| RCE Holdings Ltd | Real estate | 2021 |
| Rcjh Properties Limited | Households | 2019 |
| Rdawsonelectrics Ltd | Construction | 2026 |
| Reach Design Limited | Professional & scientific | 2022 |
| Reach North East Ltd | Arts & recreation | 2004 |
| Reactive Development Limited | Information & communication | 2015 |
| Realitysoft Homes Limited | Real estate | 2018 |
| Realitysoft IT Limited | Information & communication | 2025 |
| Reapivav Solutions Ltd | Information & communication | 2022 |
| Rebekkah Dooley Ltd | Professional & scientific | 2022 |
| Recovolt Ltd | Professional & scientific | 2024 |
| Recruitment Helpline Ltd | Administrative & support | 2013 |
| Red Arrow Consulting Ltd | Professional & scientific | 2014 |
| Red FOX Tree Care Limited | Administrative & support | 2023 |
| Red OR Green Ltd | Wholesale & retail | 2011 |
| Red RUM Sailors Ltd | Administrative & support | 2019 |
| Red Zebra Consulting Solutions Limited | Professional & scientific | 2018 |
| Redpath Leisure Ltd | Information & communication | 2025 |
| Reed & Co Capital Ltd | Households | 2025 |
| Regal Sandwich Stop Limited | Hospitality | 2011 |
| Regional Medical Services (Southern) Limited | Administrative & support | 2016 |
| Regular Jo's Ltd | Hospitality | 2015 |
| Relax Travel Limited | Transport & logistics | 2002 |
| Remojo Ltd | Information & communication | 2019 |
| Renewable OIL Services Limited | Construction | 2008 |
| Renewable-Energy-Company UK Limited | Construction | 2017 |
| Resin D'Etre Limited | Professional & scientific | 2007 |
| Resio Limited | Information & communication | 2018 |
| Resource Legal Limited | Financial services | 2003 |
| Reto Group Limited | Wholesale & retail | 2025 |
| Revgear Europe Limited | Wholesale & retail | 2016 |
| RF Coatings Ltd | Construction | 2022 |
| RH Writes Ltd | Arts & recreation | 2025 |
| Rhumbline Limited | Information & communication | 2009 |
| Richard Pickles Limited | Real estate | 1988 |
| Richard W Milne Ltd | Extraterritorial | 2022 |
| Richards Podiatry Limited | Health & social care | 2021 |
| Ricky Graham Limited | Information & communication | 2017 |
| Ridley Electricals Limited | Construction | 2015 |
| Right Choice Roofing and Reclamation Services Ltd | Construction | 2022 |
| Riley's Fish Shack Limited | Hospitality | 2015 |
| Riley's Fish Shop Limited | Wholesale & retail | 2018 |
| RIM Management Ltd | Information & communication | 2017 |
| Rise and Radiate Recovery Ltd | Administrative & support | 2023 |
| Rise and Shine Playgroup Limited | Education | 2014 |
| Rise Compliance Limited | Professional & scientific | 2022 |
| Rise Health and Wellbeing Ltd | Administrative & support | 2025 |
| Rise Lettings Group Limited | Real estate | 2022 |
| Rise North East | Arts & recreation | 2010 |
| River Raine Developments Ltd | Construction | 2023 |
| RJ Gold & Watches Limited | Wholesale & retail | 2025 |
| RJE Renewables Ltd | Construction | 2025 |
| RJT People Development Ltd | Administrative & support | 2026 |
| RJW Services Ltd | Other services | 2023 |
| RK Live Services Ltd | Arts & recreation | 2025 |
| RKM Capital Limited | Professional & scientific | 2012 |
| RLD Consultancy Ltd | Professional & scientific | 2026 |
| RLJ Properties Ltd | Real estate | 2025 |
| Rljj Consultancy Ltd | Professional & scientific | 2026 |
| RLS Property Investments Limited | Real estate | 2018 |
| RMS Electrical Engineering Limited | Construction | 2013 |
| RMS Engineering Consultants Ltd | Professional & scientific | 2025 |
| ROB Cramman Fire Ltd | Public administration | 2025 |
| Robb Inspection Services Ltd | Construction | 2012 |