| Eventival Ltd | Arts & recreation | 2019 |
| Evie Loves Toast Limited | Wholesale & retail | 2020 |
| Excelpoint Limited | Information & communication | 2004 |
| EXO Grade Ltd | Wholesale & retail | 2022 |
| EXO Grading Ltd | Wholesale & retail | 2022 |
| EXO Grafix Ltd | Wholesale & retail | 2022 |
| Exortus Ltd | Arts & recreation | 2020 |
| Extratime Gifts Ltd | Manufacturing | 2015 |
| F & B Property Developments Limited | Hospitality | 2020 |
| F S Industrial Maintenance Limited | Manufacturing | 2016 |
| FAB Shop Limited | Manufacturing | 2009 |
| Fab-Tech(Uk) Ltd | Extraterritorial | 2024 |
| Fairfield House Limited | Hospitality | 2012 |
| Fame Media Tech Limited | Information & communication | 2018 |
| Fangdale Financial Limited | Financial services | 2003 |
| Fawcett Goods Ltd | Extraterritorial | 2025 |
| FAY Donaldson Music Limited | Information & communication | 2023 |
| FBH Roofing & Cladding Limited | Construction | 2020 |
| Fend Recruitment Ltd | Manufacturing | 2024 |
| Finley Holdings Ltd | Professional & scientific | 2015 |
| Finley Leisure Ltd | Arts & recreation | 2015 |
| Finley Structures Ltd | Manufacturing | 2000 |
| Fire-Tech Engineering Ltd | Manufacturing | 2010 |
| First Stop Property Solutions Ltd | Administrative & support | 2011 |
| Fitpro Education Ltd | Extraterritorial | 2012 |
| Fixin’ Vixen Logistics Ltd | Transport & logistics | 2025 |
| Flagpoles Limited | Extraterritorial | 1993 |
| Flawless Organics Limited | Wholesale & retail | 2018 |
| Florian Logistics Ltd | Transport & logistics | 2017 |
| Focus Cladding Holdings Limited | Construction | 2020 |
| Forest Park School Ltd | Education | 2023 |
| Forget ME NOT Pet Crematorium Limited | Other services | 2004 |
| Foster Groundworks Limited | Construction | 2006 |
| Foundry & Fable Ltd | Manufacturing | 2024 |
| Four Plus Limited | Professional & scientific | 2025 |
| FOX GAS Supplies Limited | Wholesale & retail | 2003 |
| Fracks Transport Limited | Transport & logistics | 1982 |
| Frances Stays Ltd | Real estate | 2025 |
| Fresh (Aycliffe) Ltd | Hospitality | 2023 |
| Fulbeck Holdings Limited | Financial services | 2020 |
| Fulbeck Limited | Manufacturing | 2006 |
| Full Stack Collective Ltd | Professional & scientific | 2025 |
| Future Destinations Ltd | Transport & logistics | 2026 |
| Future Focus AP Ltd | Education | 2024 |
| G Brown Building & Roofing Services Ltd | Construction | 2025 |
| G Pallister & SON Farming Limited | Agriculture & fishing | 2007 |
| G S Rudd Properties Limited | Construction | 2025 |
| G Stiller (Transport) Limited | Financial services | 2019 |
| G T Coatings Limited | Manufacturing | 1954 |
| Gadget Madness Ltd | Wholesale & retail | 2020 |
| Garage 85 Auto Centre Limited | Wholesale & retail | 2018 |
| Garden Cottage Lettings Ltd | Real estate | 2025 |
| Garden Path Grounds Maintenance Ltd | Administrative & support | 2024 |
| Gardena GB Ltd | Manufacturing | 1908 |
| Gardena UK Limited | Wholesale & retail | 1999 |
| Gardner's Yard Limited | Wholesale & retail | 2015 |
| Gardners Guns Limited | Wholesale & retail | 2004 |
| Geddes Holdings (NE) Limited | Financial services | 2021 |
| Geospatial Consultants UK Ltd | Professional & scientific | 2026 |
| GES Recycling Ltd. | Water & waste | 2012 |
| Gestamp Tallent Limited | Manufacturing | 1948 |
| GET SET Go LET Ltd | Real estate | 2023 |
| Ghobadi Trading Limited | Manufacturing | 2025 |
| Ginja Ninja Ltd | Professional & scientific | 2025 |
| Glenfield Distilleries Ltd | Manufacturing | 2024 |
| Global Health Support Ltd | Health & social care | 2021 |
| Global Transnational Education Network CIC | Education | 2022 |
| Glow Church UK Ltd | Education | 2013 |
| GNA Automotive Limited | Professional & scientific | 2016 |
| Go Geothermal Ltd | Wholesale & retail | 2006 |
| GO2 Renewables Ltd | Construction | 2021 |
| Gold Couture Limited | Wholesale & retail | 2019 |
| Golden Paws Dog Grooming Ltd | Other services | 2022 |
| Gracloem Holdings Ltd | Financial services | 2009 |
| Graph's Gaff Ltd | Hospitality | 2023 |
| Grass Roots Agri Trucking & Agricultural Ltd | Wholesale & retail | 2026 |
| GRD Retail Ltd | Wholesale & retail | 2018 |
| Great Aycliffe Garden Guild C.I.C. | Wholesale & retail | 2023 |
| Great Price Buy NOW Ltd | Wholesale & retail | 2025 |
| Green Arts Newton Aycliffe Community Interest Company | Arts & recreation | 2023 |
| Green Moor Enterprises Ltd | Administrative & support | 2025 |
| Green Power Servicing Limited | Manufacturing | 2018 |
| Greenwell GAS Services Ltd | Construction | 2019 |
| Greystone Carpentry & Construction Limited | Construction | 2019 |
| Greywood Leisure Ltd | Arts & recreation | 2025 |
| Groundwork North East | Other services | 1992 |
| Group Sport Limited | Arts & recreation | 2024 |
| Gserry Ltd | Arts & recreation | 2023 |
| GYR Investments Limited | Professional & scientific | 2015 |
| H & L Property Maintenance Limited | Professional & scientific | 2006 |
| Hackett Rigging NE Ltd | Construction | 2025 |
| Hall JO Limited | Wholesale & retail | 2025 |
| Hammer & Spade DIY Services Ltd | Other services | 2019 |
| Hammerflip Limited | Information & communication | 2015 |
| Happy Land Adventures Ltd | Extraterritorial | 2023 |
| Harold Howe Electronics Limited | Professional & scientific | 2010 |
| Harper & Vale Ltd | Other services | 2025 |
| Harrison Brown Financial Services Limited | Financial services | 2003 |
| Harrison External Display Systems Limited | Extraterritorial | 2001 |
| Harrison Flagpoles Limited | Extraterritorial | 1999 |