| Charlie Armitage Properties Ltd | Construction | 2022 |
| Charlies Mill Ltd | Agriculture & fishing | 2019 |
| Charlton Stores Management Company Limited | Households | 2024 |
| Chart Safeguarding Law and Training Ltd | Health & social care | 2024 |
| Charteroak (South West) Limited | Financial services | 2019 |
| Chartwell Electro-Acoustics Limited | Manufacturing | 2015 |
| Chase Groundworks SW Limited | Construction | 2017 |
| Chdz Investments Limited | Real estate | 2022 |
| Check Book Limited | Professional & scientific | 1999 |
| Cheechis Limited | Hospitality | 2015 |
| Chefshare Catering Limited | Hospitality | 2019 |
| Chelston Medical Limited | Health & social care | 2017 |
| CHI & Sons Construction Ltd | Construction | 2019 |
| Children and Families in Grief Limited | Health & social care | 2003 |
| Chiltech Limited | Administrative & support | 2015 |
| Chipley Farm Limited | Agriculture & fishing | 2020 |
| Chitahealthcare Ltd | Health & social care | 2025 |
| Chockland Road Management Company Limited | Extraterritorial | 1998 |
| Choice Accessories Limited | Wholesale & retail | 2019 |
| Choose Plants Limited | Manufacturing | 2021 |
| Chris Cook Building Services Limited | Construction | 2012 |
| Chris COX Limited | Construction | 2003 |
| Chris Darke Paving & Landscaping Ltd | Administrative & support | 2026 |
| Chris Frediani Plastering Limited | Construction | 2010 |
| Chris Honour Racing Ltd | Arts & recreation | 2023 |
| Christie Automotive Ltd | Wholesale & retail | 2016 |
| Christina's Newton Abbot Limited | Hospitality | 2013 |
| Christopher Scales Ltd | Real estate | 2024 |
| Christy W-S Ltd | Professional & scientific | 2025 |
| Chudleigh Chapel Court Management Company Limited | Households | 2015 |
| Chudleigh Chippy Ltd | Hospitality | 2025 |
| Chudleigh Knighton Pre-School Limited | Education | 2010 |
| Chudleigh Legal Services Limited | Professional & scientific | 2015 |
| Chudley Associates Limited | Professional & scientific | 2017 |
| Church Court (Torquay) Limited | Real estate | 2014 |
| Church House Associates Limited | Financial services | 2012 |
| Church House Drive Limited | Households | 2013 |
| Church House Inn Holne Ltd | Hospitality | 2019 |
| Church Radiologists Ltd | Health & social care | 2019 |
| Church View Kingsteignton Limited | Construction | 2015 |
| Churchford Property Care Limited | Construction | 2008 |
| Ciaran Mcclennon Building Contractors Limited | Construction | 2013 |
| Cine Vista Limited | Information & communication | 2005 |
| Cinegear Limited | Administrative & support | 2011 |
| Circle 8 C Store Limited | Wholesale & retail | 2012 |
| Circle One Surf Ltd | Financial services | 2023 |
| Circlewise CIC | Professional & scientific | 2020 |
| Circulux EF Limited | Professional & scientific | 2022 |
| City Noodle Bar Limited | Hospitality | 2018 |
| CJ Gilbert Ltd | Professional & scientific | 2024 |
| Cj's Bar (SW) Ltd | Wholesale & retail | 2025 |
| CJP Engineering Services Limited | Manufacturing | 2016 |
| CK Developments London Limited | Construction | 2019 |
| CKM Beauty & Aesthetics Ltd | Other services | 2025 |
| Clad Scaffolding Ltd | Construction | 2025 |
| Claire Gardin Consulting Ltd | Professional & scientific | 2025 |
| Clarity Computers Limited | Other services | 2000 |
| Clarity Copiers (Holdings) Limited | Professional & scientific | 1999 |
| Clarity Copiers Limited | Wholesale & retail | 1977 |
| Clarity HR South West Limited | Administrative & support | 2025 |
| Classic Bike Revival Ltd | Wholesale & retail | 2021 |
| Classic Window & Conservatory Company Ltd | Construction | 1996 |
| Claudia Aesthetic Practitioner Ltd | Other services | 2021 |
| Claudia Dorsch Interior Design Limited | Other services | 2009 |
| Cleancutts Hygienic Solutions Limited | Administrative & support | 2008 |
| Cleaneco Totnes Limited | Administrative & support | 2016 |
| Cleaners R US Devon Ltd | Households | 2013 |
| Cleaners R US Midlands Limited | Other services | 2014 |
| Cleaners R US Plymouth Ltd | Other services | 2012 |
| Clear Asbestos Solutions Ltd | Construction | 2014 |
| Clearly Glass Ltd | Construction | 2012 |
| Cleave Hill Properties Limited | Real estate | 1996 |
| Cleaves Plumbing & Heating Ltd | Construction | 2019 |
| Clemence Roofing Limited | Construction | 2022 |
| Clennon Developments Limited | Construction | 1969 |
| Clennon Properties Limited | Real estate | 2018 |
| Clifford Friend Ltd | Construction | 2009 |
| Climatic Properties Limited | Real estate | 1998 |
| Climb Global Solutions Holdings UK Ltd | Wholesale & retail | 2020 |
| Climb Global Solutions Ltd | Wholesale & retail | 1982 |
| Clinical Design Technologies Group Ltd | Manufacturing | 2026 |
| Clinical Education | Education | 2014 |
| Clive Davey Haulage Limited | Transport & logistics | 2012 |
| Clockwork Holdings (SW) Ltd. | Professional & scientific | 2017 |
| Clockwork Marketing and Direct Mail Limited | Information & communication | 2003 |
| Cloud Wireless Ltd | Information & communication | 2013 |
| CMC Assessment & Training Ltd | Construction | 2025 |
| Coaching and Education Services CIC | Education | 2015 |
| Coast 2 Coast Comps Ltd | Arts & recreation | 2025 |
| Coast Business Solutions Ltd | Information & communication | 2009 |
| Coast, Town & Country Windows Limited | Manufacturing | 2011 |
| Coastal Anaesthesia Limited | Health & social care | 2012 |
| Coastal Catering Croyde Ltd | Hospitality | 2021 |
| Coastal Estates South West Ltd | Real estate | 2022 |
| Coastal Hideaways Limited | Real estate | 2022 |
| Coastal Home Building Ltd | Construction | 2025 |
| Coastal Living Property Management Limited | Other services | 2014 |
| Cobalt Film Ltd | Information & communication | 2024 |
| Cobel Surveyors Limited | Construction | 2023 |
| Cobell Limited | Extraterritorial | 2023 |