| Caliber & Bore Limited | Wholesale & retail | 2010 |
| Cambium Networks, Ltd | Information & communication | 2011 |
| Cameron J ZAB Ltd | Agriculture & fishing | 2018 |
| Cameron Scott Limited | Professional & scientific | 2004 |
| Camilleri Clinical Psychology Ltd | Health & social care | 2016 |
| Campbell Build Limited | Construction | 2018 |
| Camperworx Ltd | Manufacturing | 2020 |
| Canec Ltd | Construction | 2016 |
| Cannon Commercials Limited | Wholesale & retail | 2003 |
| Canopy Crops Ltd | Wholesale & retail | 2023 |
| CAP Teignbridge CIC | Professional & scientific | 2019 |
| Cape Livia Group Limited | Professional & scientific | 2023 |
| Capital Restaurant & Bars Group Limited | Hospitality | 2024 |
| Capital View International Limited | Construction | 2004 |
| Caps (UK) Ltd | Financial services | 2000 |
| Cara Training and Consultancy Ltd | Other services | 2026 |
| Caraston Hall Housing | Hospitality | 2007 |
| Cardiac Solutions South West Limited | Health & social care | 2019 |
| Cardinal Estates (SW) Ltd | Real estate | 2018 |
| Careright Homecare Limited | Health & social care | 2010 |
| Carew Services Limited | Administrative & support | 2002 |
| Careyourway Franchising Ltd | Financial services | 2021 |
| Careyourway Group Ltd | Financial services | 2022 |
| Careyourway Homecare Ltd | Health & social care | 2005 |
| Caricom Dream Limited | Administrative & support | 2025 |
| Caritas Diocese of Plymouth | Other services | 2023 |
| Carl Cosby Ltd | Extraterritorial | 2025 |
| Carlton House (Paignton) Limited | Professional & scientific | 2005 |
| Carlton House Exmouth Limited | Real estate | 2013 |
| Carol C. Collections Limited | Manufacturing | 2003 |
| Carpenters Court (Newton Abbot) Management Company Limited | Households | 1989 |
| Carrick Johnson Letting & Property Management Ltd | Real estate | 2024 |
| Carson Moore Properties Limited | Real estate | 2016 |
| Carter Hamilton Ltd | Professional & scientific | 2019 |
| Casa (SW) Limited | Financial services | 2022 |
| Casa Teva Ltd | Real estate | 2017 |
| Casino Select Limited | Arts & recreation | 2006 |
| Castle Bricklaying Services Ltd | Construction | 2021 |
| Castle Court Consultancy Limited | Real estate | 2023 |
| Castle Dore Limited | Construction | 2019 |
| Castle Hill Insolvency Ltd | Other services | 2017 |
| Castleford Engineering Limited | Construction | 2015 |
| Castlewood Letting Services Limited | Real estate | 2013 |
| Castodia Ltd | Information & communication | 2026 |
| Catherine House Medical Services Limited | Health & social care | 2017 |
| Catholic Children's Society (Plymouth) | Health & social care | 1981 |
| Cattermole Homes Ltd | Real estate | 2025 |
| Cavendish Estate Property Limited | Real estate | 2011 |
| Cb&A Primary Healthcare Limited | Health & social care | 2025 |
| CC Realisations (2024) LLP | | 2008 |
| CCM Works Limited | Agriculture & fishing | 2026 |
| CDI International Holdings Ltd | Financial services | 2024 |
| CDT Services Limited | Education | 2016 |
| Cecil Street Properties Limited | Real estate | 2023 |
| Cedar Court (Richmond) Limited | Households | 1993 |
| Celsius Systems UK Ltd | Professional & scientific | 2006 |
| CEN Fabrications Ltd | Professional & scientific | 2010 |
| Centek Holdings Limited | Financial services | 2011 |
| Centek Limited | Manufacturing | 2001 |
| Centek Overseas Holdings Limited | Financial services | 2011 |
| Centek Properties Limited | Real estate | 2006 |
| Centek Technologies Limited | Financial services | 2018 |
| Central Garage Bishop Ltd | Wholesale & retail | 2020 |
| Central Garages (Moretonhampstead) Ltd | Wholesale & retail | 2024 |
| Central Hall Bristol Limited | Households | 2014 |
| Centrax Industries Limited | Professional & scientific | 2000 |
| Centrax International Limited | Manufacturing | 1975 |
| Centrax Limited | Manufacturing | 1957 |
| Centrax Power Projects (Holdings) Limited | Professional & scientific | 2008 |
| Centrax Trustees Limited | Financial services | 1957 |
| Centre Line Properties Limited | Construction | 1996 |
| Centristic Limited | Manufacturing | 1981 |
| Centum Books Limited | Information & communication | 2011 |
| Centum Publishing Limited | Information & communication | 2013 |
| CGS Design & Build Ltd | Construction | 2024 |
| Cgsl Consultants Ltd | Professional & scientific | 2020 |
| CGW Groundworks & Drainage Ltd | Construction | 2021 |
| CGX AI Ltd | Education | 2026 |
| CH Alliance C.I.C. | Extraterritorial | 2017 |
| CH Developments South West Ltd | Construction | 2023 |
| CH Site Engineering Ltd | Construction | 2022 |
| Chadwick Complimentary Ltd | Health & social care | 2024 |
| Chadwickventures Ltd | Professional & scientific | 2026 |
| Chagford Florist LP | | 2013 |
| Chagford Market Garden Ltd | Agriculture & fishing | 2019 |
| Chagford Regenerative Farmers CIC | Agriculture & fishing | 2023 |
| Chamberlains Rentals Limited | Real estate | 2011 |
| Chanbury's Woodfired Pizza Ltd | Hospitality | 2021 |
| Chandler Technology Limited | Information & communication | 2014 |
| Chang Media Marketing Ltd | Information & communication | 2017 |
| Changvilla Investments Limited | Real estate | 1960 |
| Channel View Management Services Limited | Health & social care | 2013 |
| Chapel Green (Bideford) Management Company Ltd | Households | 2026 |
| Chard Chiropractic Clinic Limited | Other services | 2019 |
| Charles Blake + Associates Limited | Professional & scientific | 2005 |
| Charles Cleaning Limited | Households | 2021 |
| Charles Darrow Holdings Limited | Real estate | 2022 |
| Charles Darrow Ltd | Real estate | 2013 |
| Charles Scott Interiors LLP | | 2024 |
| Charlie a Allen Consulting Limited | Professional & scientific | 2018 |