| Beaverton Limited | Transport & logistics | 2020 |
| Beemoved.Com Limited | Transport & logistics | 2007 |
| Belay Rope Access Ltd | Professional & scientific | 2013 |
| Benecura Limited | Wholesale & retail | 2025 |
| Benwick Kennels & Cattery Ltd | Other services | 2025 |
| Bespoke Build Sussex Ltd | Administrative & support | 2018 |
| Bevan Funnell Group Limited | Manufacturing | 2006 |
| Bigtomskitchen Ltd | Hospitality | 2018 |
| Bike Banshee Limited | Manufacturing | 2013 |
| Bishopstone Building Contractors Limited | Construction | 2012 |
| Bishopstone Property Maintenance Limited | Construction | 2025 |
| BL Engineering Consultancy Services Ltd | Professional & scientific | 2020 |
| Black Moon Distillery Ltd | Manufacturing | 2020 |
| Blecs Limited | Professional & scientific | 2024 |
| Bloomsbury Building Consultancy Ltd | Professional & scientific | 2025 |
| Bloomsbury Waste Management Ltd | Water & waste | 2026 |
| Blue Dart Solutions Ltd | Information & communication | 2017 |
| BN Scaffolding Limited | Construction | 2019 |
| Boat Exhibitions Limited | Administrative & support | 2002 |
| Bowerman Gill Limited | Other services | 2008 |
| Bowfinity Limited | Wholesale & retail | 2023 |
| Bowman's Premium Limited | Wholesale & retail | 2010 |
| Bridge Mews 8 -10 Bridge Street Freehold Company Limited | Households | 2022 |
| Bright White Innovation Limited | Wholesale & retail | 2018 |
| Bright White Living Ltd | Wholesale & retail | 2024 |
| Bright-Tech Investments Group Limited | Financial services | 2017 |
| Brighton Archiving Limited | Administrative & support | 2011 |
| Brighton Cabs Co Ltd | Transport & logistics | 2024 |
| Brighton Developments ( Southern) Ltd | Construction | 2023 |
| Brighton Guitars Limited | Arts & recreation | 2008 |
| Brighton Motorama Limited | Wholesale & retail | 2006 |
| Brighton Properties Maintenance Service Ltd | Construction | 2015 |
| Brightwell Dosing Limited | Manufacturing | 1960 |
| Broe & Co Architects LLP | | 2017 |
| Broe Architecture Limited | Professional & scientific | 2019 |
| BSPOK3 Limited | Construction | 2018 |
| Bspoke FP Limited | Professional & scientific | 2026 |
| Building Integration and Automation Services Limited | Construction | 2015 |
| Building Safety Associates Ltd | Professional & scientific | 2018 |
| Butler Court Leaseholders' RTM Company Limited | Households | 2018 |
| Bwhl Group Limited | Administrative & support | 2012 |
| Byinone Ltd | Wholesale & retail | 2023 |
| C Cohen Tree Care Ltd | Administrative & support | 2019 |
| Caats Ltd. | Professional & scientific | 2017 |
| Callender Creates Ltd | Information & communication | 2007 |
| Campaign Whale | Other services | 1997 |
| CAN Catering Limited | Hospitality | 2019 |
| Canwegame Ltd | Information & communication | 2025 |
| Cape Community (Valencay and Versailles) Freehold Company Limited | Households | 2014 |
| Cape Falaise Limited | Households | 2014 |
| Capitech Limited | Real estate | 2015 |
| Carealign Support Ltd. | Administrative & support | 2025 |
| Cargo Flow Agency Limited | Transport & logistics | 2021 |
| Carraway Property Ltd | Real estate | 2020 |
| CC Electrical Sussex Ltd | Construction | 2026 |
| CCS Plumbing and Heating Solutions Limited | Construction | 2017 |
| Cement Arts Ltd | Arts & recreation | 2025 |
| Central House (Telscombe Cliffs) Limited | Real estate | 2006 |
| Cflo Production Services Ltd | Information & communication | 2021 |
| Charles COX Limited | Administrative & support | 2010 |
| Chess Removals and Storage Limited | Extraterritorial | 2020 |
| Chip Art Ltd | Arts & recreation | 2024 |
| Choctaw Choppers Limited | Wholesale & retail | 2025 |
| Chris Grant Carpets & Flooring Ltd | Construction | 2025 |
| Chyngton House Estate Limited | Households | 1983 |
| Cinevisionary Ltd | Education | 2024 |
| Clairville Management Company Limited | Real estate | 1990 |
| Claremont Designs Ltd | Manufacturing | 2012 |
| Clean by the C Ltd | Administrative & support | 2025 |
| Clean Home Haven Ltd | Transport & logistics | 2024 |
| Cleaning Company and Partners Ltd | Administrative & support | 2024 |
| Clew Communications Limited | Professional & scientific | 2001 |
| Cmd-Shift-R Ltd | Information & communication | 2008 |
| Coddenham Limited | Other services | 2023 |
| Colgate and Gray Land Limited | Real estate | 1948 |
| Collingwood Properties (Eastbourne) Limited | Households | 1998 |
| Combustion Productions Ltd | Information & communication | 2025 |
| Community Transport for the Lewes Area | Transport & logistics | 2002 |
| Complete Properties (Southern) Ltd | Construction | 2022 |
| Complete Property Solutions (Sussex) Limited | Construction | 2011 |
| Complete Rendering Systems Ltd | Construction | 2010 |
| Complete Rendering Systems Repairs and Remedials Ltd | Construction | 2022 |
| Compliance Testing & Solutions Limited | Administrative & support | 2019 |
| Confecto Limited | Wholesale & retail | 2026 |
| Conforta-La Ltd | Wholesale & retail | 2026 |
| Constellation Capital Ltd | Real estate | 2021 |
| Consult Group Limited | Administrative & support | 2021 |
| Control Pollution Limited | Water & waste | 2011 |
| Coombe Lodge (Seaford) Residents Association Limited | Households | 1974 |
| Copperfield House (Eastbourne) Management Limited | Real estate | 1993 |
| Core Cable Networks Limited | Construction | 2022 |
| Cosy Toes Carpets Limited | Wholesale & retail | 2017 |
| Cowa Ltd | Wholesale & retail | 2022 |
| Creekside Music Ltd | Information & communication | 2019 |
| Crossfit Chimera Ltd | Arts & recreation | 2023 |
| Crowdstop.Com Limited | Administrative & support | 2002 |
| CT Electrical Compliance Ltd | Construction | 2020 |
| Culture Connect Project CIC | Education | 2024 |
| Curzon Penthouses Limited | Real estate | 2024 |
| Cyberside Limited | Information & communication | 2026 |