| Stokejetwash Ltd | Administrative & support | 2023 |
| Stone Circle Writing Ltd | Professional & scientific | 2021 |
| Stone Dominoes Football Club Ltd | Arts & recreation | 2022 |
| Stone Label & Security Printers Limited | Manufacturing | 2007 |
| Stone Spice Group Limited | Hospitality | 2024 |
| Stonehall Ltd | Manufacturing | 2015 |
| Stonehouse Three One Ltd | Professional & scientific | 2020 |
| Stonetown Socks Limited | Manufacturing | 2011 |
| Stonewall Motors Ltd | Wholesale & retail | 2020 |
| Stonewright Developments Limited | Construction | 2024 |
| Stonewright Properties Limited | Real estate | 2024 |
| Stoord Ltd | Wholesale & retail | 2026 |
| Storage Solutions for YOU Limited | Transport & logistics | 2019 |
| Storm Advertising & Design Ltd | Professional & scientific | 2007 |
| Stove Glass Replacements Limited | Wholesale & retail | 2013 |
| Strachan Turf Consultancy Ltd | Professional & scientific | 2018 |
| Straight Cabs Limited | Transport & logistics | 2025 |
| Strategi Executive Consulting Limited | Professional & scientific | 2025 |
| Strategi Global Solutions Limited | Professional & scientific | 2025 |
| Strategi Solutions Group Holdings Limited | Professional & scientific | 2023 |
| Strategi Solutions Group Limited | Professional & scientific | 2009 |
| Strategic Integrated Delivery Limited | Professional & scientific | 2024 |
| Stratheden Medical and Orthodontic Services Limited | Health & social care | 2015 |
| Stratstep Consulting Limited | Professional & scientific | 2019 |
| Stratstep Group Holding Limited | Transport & logistics | 2020 |
| Stratstep Technology Limited | Manufacturing | 2020 |
| Streat Newcastle Ltd | Hospitality | 2019 |
| Streetalliance Ltd | Extraterritorial | 2019 |
| Strength Feeds Limited | Hospitality | 2023 |
| Stroka Clinics London Limited | Health & social care | 2026 |
| Stroom Electrical Engineering Limited | Professional & scientific | 2015 |
| Stubbs Trading Education Ltd | Information & communication | 2025 |
| Stubä Systems Limited | Information & communication | 2025 |
| Studio 9 Music Ltd | Information & communication | 2021 |
| Studio Alex Ltd | Professional & scientific | 2025 |
| Studio D2 Architects Ltd | Professional & scientific | 2015 |
| Studio GMI Ltd | Information & communication | 2025 |
| Study Property Consultancy Limited | Professional & scientific | 2023 |
| Subco Engineering Ltd | Professional & scientific | 2023 |
| Subiton Bidco UK Limited | Financial services | 2022 |
| Subscription Capital Ltd | Administrative & support | 2025 |
| Sugartrap AI Ltd | Information & communication | 2025 |
| SUITE167 Limited | Professional & scientific | 2025 |
| SUITE2 Limited | Real estate | 2020 |
| Summit Fit OUT Limited | Administrative & support | 2026 |
| Summit Psychology Services Ltd | Education | 2022 |
| Sunbuild Estates Limited | Real estate | 2001 |
| Sunhill Medical Services Limited | Health & social care | 2019 |
| Sunshinegym Ltd | Extraterritorial | 2015 |
| Super Target Ltd | Wholesale & retail | 2026 |
| Supreme Vehicles Ltd | Wholesale & retail | 2024 |
| Sureseal Properties Ltd | Real estate | 2025 |
| Surface Revival Limited | Construction | 2025 |
| Survi Ltd | Professional & scientific | 2019 |
| Sutherland Court RTM Company Limited | Households | 2013 |
| SVM Technologies Ltd | Information & communication | 2020 |
| Swan Health and Rehabilitation Limited | Health & social care | 2017 |
| Sweet September Ltd | Wholesale & retail | 2025 |
| Swift Response Properties Ltd | Real estate | 2026 |
| Swiftmila Ltd | Wholesale & retail | 2025 |
| Swinchurch Farms Limited | Agriculture & fishing | 1965 |
| Swinglish Properties Limited | Real estate | 2024 |
| Swiss International Ltd | Information & communication | 2026 |
| Swissamc Ltd | Financial services | 2023 |
| SY Medical Services Limited | Health & social care | 2020 |
| Symmo & Sons Ltd | Professional & scientific | 2013 |
| SYN3RGY Ltd | Manufacturing | 2023 |
| Synchro Mortgage Solutions Limited | Financial services | 2008 |
| Synergy Accounting Ltd | Professional & scientific | 2007 |
| Synergy Health Group Ltd | Financial services | 2023 |
| Synergyinspine Private Limited | Health & social care | 2022 |
| Synq Project Limited | Arts & recreation | 2025 |
| Syxi Ltd | Wholesale & retail | 2025 |
| T & P Construction Limited | Construction | 2007 |
| T - Scan Holdings Limited | Information & communication | 2010 |
| T - Scan Limited | Information & communication | 2011 |
| T and S Leisure Ltd | Hospitality | 2012 |
| T G Golf Limited | Arts & recreation | 2018 |
| T.C. Cornwell Limited | Real estate | 1999 |
| T.D.L.E Ltd | Construction | 2015 |
| T.N. Direct Limited | Information & communication | 2008 |
| Tadar Group Ltd | Wholesale & retail | 2016 |
| Tadros Group Ltd | Real estate | 2024 |
| TAH Property Ltd | Hospitality | 2025 |
| Tahat Ltd | Construction | 2017 |
| Tailor Made Conservatories Limited | Wholesale & retail | 1988 |
| Tailored Slate and Stone Ltd | Wholesale & retail | 2022 |
| Talbott's Biomass Power Limited | Professional & scientific | 2026 |
| Talke Tooling Limited | Manufacturing | 2000 |
| Tamanu Property Holdings Ltd | Households | 2026 |
| Tanu Beauty Salon Limited | Other services | 2025 |
| Tanya Ireland Limited | Manufacturing | 2017 |
| Tanya Mack & Co Ltd | Professional & scientific | 2016 |
| Taradiology Limited | Health & social care | 2024 |
| Tarpey Woodfine Architects Limited | Professional & scientific | 2009 |
| Tasty+Kitchen Limited | Wholesale & retail | 2019 |
| Tattoos at 6 Ltd | Arts & recreation | 2026 |
| Taylor Made Property Investment Co Limited | Real estate | 2010 |
| Taylor Wilcox Commercial Ltd | Real estate | 2009 |
| TBA PR London Ltd | Professional & scientific | 2017 |