| Regal Lion and Eagle Security Limited | Administrative & support | 2025 |
| Regina Industries Limited | Manufacturing | 1949 |
| Reheat Technical Solutions Ltd | Construction | 2022 |
| Relex Solutions UK Limited | Information & communication | 1998 |
| Renew Hair and Body Care Limited | Other services | 2026 |
| Rennard Consulting Limited | Professional & scientific | 2019 |
| Reset Recovery Ltd | Other services | 2026 |
| Resilience UK Care Limited | Health & social care | 2020 |
| Resin Systems Ltd | Construction | 2023 |
| Restmore Limited | Wholesale & retail | 2018 |
| Retaillservices Limited | Wholesale & retail | 2025 |
| Retrofit Laboratories Ltd | Professional & scientific | 2022 |
| Reverie London Limited | Hospitality | 2016 |
| RGH Network Services Limited | Information & communication | 2013 |
| RH Plant Hire Holdings Ltd | Professional & scientific | 2009 |
| Rheumat Ltd | Health & social care | 2023 |
| Rhiwlas Care Ltd | Health & social care | 2022 |
| Rice Building Contracts (NI) Limited | Construction | 2014 |
| Richard Buckley Limited | Construction | 1963 |
| Richard Dalton Ltd | Manufacturing | 2009 |
| Richard Hardie (Gosforth) Limited | Extraterritorial | 1985 |
| Richard Hardie (Stanley) Ltd | Extraterritorial | 1987 |
| Richard Hardie Limited | Wholesale & retail | 1972 |
| Richard Hunt Investments Limited | | 2009 |
| Richard Jacobs Pensions Ltd | Financial services | 1998 |
| Richmond Court (Oldbury) Management Company Limited | Households | 2002 |
| Ricy Trans Ltd | Transport & logistics | 2016 |
| Riders Group Limited | Other services | 2015 |
| Ridgways Hearing Care Limited | Professional & scientific | 2012 |
| Rieter-Scragg Limited | Manufacturing | 1981 |
| Ringing Bells Limited | Construction | 2023 |
| Rinil Limited | Health & social care | 2018 |
| Rio’S Barbering Studio Ltd | Other services | 2026 |
| Rischio Ltd | Real estate | 2017 |
| Ritishu Limited | Wholesale & retail | 2025 |
| River View Holidays Limited | Hospitality | 2003 |
| RJA Consulting Limited | Professional & scientific | 2022 |
| RKC Plastering Limited | Construction | 2026 |
| RL Alderley Ltd | Extraterritorial | 2024 |
| RL Lymm Ltd | Hospitality | 2023 |
| RLM Property Ltd | Real estate | 2024 |
| RLP Engineering Ltd | Manufacturing | 2009 |
| RLP Trading Ltd | Information & communication | 2025 |
| RM Automotive Car Parts Ltd | Wholesale & retail | 2022 |
| RMS Installations (Staffs) Ltd | Construction | 2017 |
| RO Lifts Ltd | Construction | 2016 |
| Roadlink North East Ltd | Construction | 2019 |
| Robin Hill Workshops Limited | Construction | 1979 |
| Robin HX Ltd | Education | 2023 |
| Rochelle Peake Properties Limited | Real estate | 2026 |
| Rockhopper Engineering Solutions Ltd | Administrative & support | 2014 |
| Rockleigh House Limited | Hospitality | 2004 |
| Rockley Stables Ltd | Administrative & support | 2004 |
| Roden Estates Limited | Administrative & support | 1997 |
| Rodgers Construction Limited | Construction | 2011 |
| Rohan Developments Limited | Construction | 2008 |
| Rohoo Rice Ltd | Hospitality | 2023 |
| Rola Alakson Properties Limited | Real estate | 2023 |
| Romanticise Limited | Wholesale & retail | 2022 |
| Romeo & Sons Transport Limited | Transport & logistics | 2018 |
| Rommco (UK) Limited | Extraterritorial | 2011 |
| Room by Julia Brown Ltd | Professional & scientific | 2025 |
| Rooney Equine Limited | Professional & scientific | 2018 |
| Roselle & Co. Ltd | Manufacturing | 2025 |
| Rosetti Games Ltd | Information & communication | 2024 |
| Rosetti Tech Ltd | Information & communication | 2011 |
| Roskell Family Holdings Ltd | Financial services | 2026 |
| Rough Media Limited | Information & communication | 2022 |
| Rowley Holdings Limited | Financial services | 2015 |
| Royals Couriers Limited | Transport & logistics | 2024 |
| Royston Jones Ltd | Construction | 2022 |
| RPB Security Limited | Administrative & support | 2024 |
| RTC Medical Solutions Ltd | Health & social care | 2016 |
| Ruddle Property Limited | Real estate | 2025 |
| Running UP Record Ltd | Information & communication | 2013 |
| Rusman Limited | Health & social care | 2019 |
| Ruth Tappin Limited | Other services | 2003 |
| Rutongci LIY Limited | Wholesale & retail | 2025 |
| Rydale Construction Ltd | Administrative & support | 2017 |
| Rydale Property Limited | Construction | 2017 |
| Rydale Roofing Limited | Construction | 2008 |
| Ryder & Stuart Limited | Wholesale & retail | 2015 |
| S & a Wholesale Limited | Wholesale & retail | 2014 |
| S & L Swim School Limited | Education | 2011 |
| S & P Retail Ltd | Wholesale & retail | 2007 |
| S a Varley Ltd | Construction | 2019 |
| S Anwer&Co Ltd | Health & social care | 2019 |
| S Forrester Engineering Limited | Manufacturing | 2015 |
| S J Etchells Holdings Limited | Financial services | 2021 |
| S P Care Clinic Limited | Health & social care | 2015 |
| S W H Financial Planning Limited | Financial services | 2010 |
| S&P Booze Limited | Wholesale & retail | 2003 |
| S&S Creative Co Ltd | Information & communication | 2025 |
| S.E.N.D GIN and Cheese CIC | Health & social care | 2023 |
| S.F. Management Limited | Real estate | 2009 |
| S.N.P.Y. Construction Ltd | Construction | 2016 |
| S5 Direct Ltd | Wholesale & retail | 2022 |
| Safe Pack AI Ltd | Information & communication | 2025 |
| Safe-T Transport Ltd | Transport & logistics | 2019 |
| Safehands Group Ltd | Administrative & support | 2026 |