| E3DESIGN Limited | Professional & scientific | 2007 |
| Ea&A (Exclusive Apparels and Accessories) Ltd | Wholesale & retail | 2012 |
| EAA Hire Ltd | Administrative & support | 2024 |
| EAA Property Ltd | Real estate | 2024 |
| Eachwick Property Investments Limited | Real estate | 2020 |
| Eachwick Property Limited | Real estate | 2020 |
| Eaga Partnership Trustee Limited | Professional & scientific | 1999 |
| Eaga Partnership Trustee Two Limited | Professional & scientific | 1999 |
| Eagle BSW Ltd | Real estate | 2026 |
| Eagle Electrical & Building Limited | Construction | 2008 |
| Eagle NDT Ltd | Professional & scientific | 2014 |
| Eagle Star House Clearance Limited | Water & waste | 2022 |
| Eagles Community Arena Limited | Arts & recreation | 2018 |
| Eagles Community Foundation | Arts & recreation | 2005 |
| Eaglestones House Clearance Limited | Transport & logistics | 2019 |
| Eaglewealth Infinity Limited | Real estate | 2020 |
| EAM Consultancy Services Ltd | Health & social care | 2021 |
| Eapt Ltd | Real estate | 2024 |
| Earl Grey Properties Ltd | Real estate | 2017 |
| Earl Jones Staffing Ltd | Other services | 2025 |
| Earl's Joinery & Construction Limited | Construction | 2021 |
| Early Adventures Ltd | Health & social care | 2016 |
| Earsdon Storage Limited | Other services | 2012 |
| Earsdon View Block a Management Company Limited | Real estate | 2016 |
| Earsdon View Block B Management Company Limited | Real estate | 2015 |
| Earsdon View Management Company Limited | Households | 2011 |
| Earson View Management Limited | Real estate | 2007 |
| Earthbond (Wellness) Ltd | Other services | 2023 |
| Earthlings Cafe Ltd | Wholesale & retail | 2025 |
| Earthmoving Limited | Construction | 2003 |
| Easdale Anaesthesia Ltd | Health & social care | 2025 |
| Easington Greyhound Stadium Limited | Real estate | 1995 |
| East and West Decorating Services (2009) Limited | Administrative & support | 2009 |
| East Architecture, Landscape, Urban Design Limited | Professional & scientific | 2005 |
| East Bridge Europe Ltd | Wholesale & retail | 2025 |
| East Cleveland Connected CIC | Health & social care | 2025 |
| East Coast Fibreglass Supplies Limited | Extraterritorial | 2018 |
| East END Car & Van Sales Ltd | Wholesale & retail | 2024 |
| East END Collective CIC | Arts & recreation | 2026 |
| East END Hand Car Wash Ltd | Administrative & support | 2025 |
| East END Liberal Club,Limited | Hospitality | 1894 |
| East Garth Builders Limited | Construction | 2025 |
| East House (Dissington) | Administrative & support | 2011 |
| East Middle Callerton Residents Management Company Limited | Households | 2019 |
| East Midlands Ltd | Wholesale & retail | 2021 |
| East Mill Residents Management Company Limited | Real estate | 2005 |
| East Powergrid Limited | Extraterritorial | 2011 |
| East Quayside (Newcastle) Management Company Limited | Real estate | 2000 |
| East Quayside Management Limited | Households | 1992 |
| East River PR Ltd | Professional & scientific | 2012 |
| East Shore Village Management Limited | Real estate | 2007 |
| East Slope Residencies Facilities Management Limited | Financial services | 2016 |
| East Slope Residencies Holdings Limited | Financial services | 2016 |
| East Slope Residencies Partner Limited | Financial services | 2016 |
| East Slope Residencies PLC | Financial services | 2016 |
| East Slope Residencies Student Accommodation LLP | | 2016 |
| East Star Group Ltd | Financial services | 2022 |
| East Wick and Sweetwater Finance (Holdings) Limited | Administrative & support | 2018 |
| East Wick and Sweetwater Projects (Finance) Limited | Administrative & support | 2018 |
| East Wick and Sweetwater Projects (Holdings) Limited | Financial services | 2015 |
| East Wick and Sweetwater Projects (Phase 1) Limited | Construction | 2015 |
| East Wick and Sweetwater Projects (Phase 2) Limited | Construction | 2015 |
| East Wick and Sweetwater Projects (Phase 3) Limited | Construction | 2015 |
| East Wick and Sweetwater Projects (Phase 4) Limited | Construction | 2015 |
| East Wick and Sweetwater Projects (Phase 5) Limited | Construction | 2015 |
| East Wick and Sweetwater Projects (Phase 7) Limited | Construction | 2015 |
| East Wick and Sweetwater Projects (Phase 7A) Limited | Construction | 2015 |
| East Yorkshire Buses Limited | Extraterritorial | 1931 |
| East Yorkshire Coach Holidays Limited | Administrative & support | 1929 |
| East Yorkshire Coaches Limited | Extraterritorial | 1937 |
| East Yorkshire Concert Tours Limited | Professional & scientific | 1987 |
| East Yorkshire Holiday Tours Limited | Extraterritorial | 1987 |
| East Yorkshire Motor Services Limited | Transport & logistics | 1926 |
| East Yorkshire Properties Limited | Extraterritorial | 1988 |
| East Yorkshire Tours Limited | Extraterritorial | 1920 |
| East Yorkshire Travel Limited | Extraterritorial | 1996 |
| Eastar Limited | Wholesale & retail | 2006 |
| Eastend Diner Food Hub Ltd | Hospitality | 2024 |
| Eastend Diner NE5 Foods Ltd | Hospitality | 2019 |
| Easter Park Cramlington Management Company Limited | Real estate | 2012 |
| Easter Park Management Limited | Households | 2012 |
| Eastern Aura Limited | Wholesale & retail | 2025 |
| Eastern Meadow Ltd | Hospitality | 2011 |
| Eastern Powergrid Limited | Extraterritorial | 2011 |
| Easternway Ltd | Real estate | 2020 |
| Easteye Limited | Hospitality | 1982 |
| Eastfield House Management Company Limited | Households | 2001 |
| Eastfields (Brett Street) Management Company Limited | Households | 2005 |
| Eastfields Residents Company Limited | Real estate | 2004 |
| Eastgarth Engineering (NE) Limited | Professional & scientific | 2021 |
| Eastgate Developments (Hexham) Limited | Real estate | 2004 |
| Eastland Network Cabling Solutions Limited | Construction | 2025 |
| Eastwood Court Limited | Households | 1982 |
| Eastwynn Limited | Professional & scientific | 2018 |
| Easy AS ... ABC Accountancy Services Limited | Professional & scientific | 2013 |
| Easy Energy Renewal Limited | Energy | 2018 |
| Easy Life JIU Jitsu Club Ltd | Wholesale & retail | 2025 |
| Easypass Limited | Education | 2025 |
| Easyport Customs UK Limited | Transport & logistics | 2021 |
| Easystay North Ltd | Wholesale & retail | 2023 |