| 3V3UK Newcastle Ltd | Arts & recreation | 2023 |
| 4 ALL Electrical NE Ltd | Wholesale & retail | 2025 |
| 4 Belle Grove Terrace (Management) Limited | Households | 2003 |
| 4 Global Safe Air Limited | Professional & scientific | 2018 |
| 4 LOW Strings Ltd | Wholesale & retail | 2022 |
| 4,5,6 and 7 Dene House Freehold Limited | Households | 2024 |
| 40/42 Burdon Terrace Management Company Limited | Households | 1975 |
| 413 Leather Ltd | Wholesale & retail | 2022 |
| 42 Heaton Grove Ltd | Administrative & support | 2015 |
| 42 ST. Georges Terrace Management Company Limited | Households | 2006 |
| 42 the Calls Hotel Limited | Hospitality | 2018 |
| 42 the Esplanade Ltd | Hospitality | 2022 |
| 45 Flaxman Road Limited | Extraterritorial | 2014 |
| 46 North Property Holdings Ltd | Real estate | 2025 |
| 48 Westgate Ltd | Hospitality | 2024 |
| 49 Sanderson Road Management Company Limited | Households | 1994 |
| 49 SBR Ltd | Real estate | 2024 |
| 4BEAT Limited | Arts & recreation | 2018 |
| 4D (North East) Ltd | Real estate | 2023 |
| 4DSPHERE Ltd | Real estate | 2024 |
| 4KIDSVISION Ltd | Health & social care | 2023 |
| 4L Private Limited | Wholesale & retail | 2024 |
| 4MEDIAS Ltd | Information & communication | 2007 |
| 4MPLIFY Ltd | Professional & scientific | 2025 |
| 4PT Limited | Information & communication | 2009 |
| 4USALL Activity Centre C.I.C. | Education | 2025 |
| 4W Properties Ltd | Real estate | 2023 |
| 4WAY Property Services Limited | Real estate | 2018 |
| 5 Armies Pens Ltd | Real estate | 2021 |
| 5 Haldane Terrace Jesmond Management Company Limited | Real estate | 2006 |
| 5 Meldon Terrace Management Company Limited | Extraterritorial | 2014 |
| 5 ST George's Terrace Management Limited | Households | 2019 |
| 5 Star Auto Repair and Car Wash Ltd | Wholesale & retail | 2024 |
| 5 Star North East Ltd | Administrative & support | 2017 |
| 5 Star PR Ltd | Professional & scientific | 2014 |
| 50/52 Shield Street Management Company Limited | Extraterritorial | 2009 |
| 5058 Property Limited | Real estate | 2016 |
| 52 Crowndale Road Freehold Limited | Households | 1992 |
| 55 Degrees Holding Limited | Real estate | 2023 |
| 55 Degrees Management Ltd | Hospitality | 2025 |
| 55 Degrees North Fire Protection Ltd | Public administration | 2025 |
| 55 Degrees North Limited | Households | 2002 |
| 55 Degrees North RTM Company Limited | Extraterritorial | 2013 |
| 555 FL Ltd | Hospitality | 2019 |
| 55TH Parallel Ltd. | Professional & scientific | 2017 |
| 59 Fern Avenue Limited | Hospitality | 1986 |
| 5G Homes Limited | Real estate | 2026 |
| 5G Technologies Europe Limited | Information & communication | 2009 |
| 5STARSOLE Limited | Wholesale & retail | 2021 |
| 6 Ashlake Road Management Limited | Extraterritorial | 2002 |
| 6 Eskdale Terrace Jesmond Management Company Limited | Households | 2002 |
| 6 Eslington Terrace Management Company Limited | Households | 1992 |
| 6 Jesmond Gardens Limited | Households | 1985 |
| 6 Months Sober Ltd | Other services | 2019 |
| 60-63 Broomlee Road Freehold Limited | Professional & scientific | 2014 |
| 61 Strathblaine Road Freehold Limited | Households | 2023 |
| 69 ST. Georges Terrace Management Company Limited | Households | 2005 |
| 6H Properties Ltd | Real estate | 2026 |
| 7 Claremont Terrace Management Company Limited | Households | 1992 |
| 7 Eslington Terrace Limited | Real estate | 1996 |
| 7 Osborne Terrace RTM Company Limited | Households | 2018 |
| 7 Star Lettings Ltd | Real estate | 2022 |
| 7-11 News Limited | Wholesale & retail | 2019 |
| 700 Acres Ltd | Administrative & support | 2018 |
| 7030DRIVE Ltd | Transport & logistics | 2026 |
| 71 ST Georges Terrace Limited | Households | 2014 |
| 79 Concept Ltd | Information & communication | 2025 |
| 8 Signals Group Limited | Financial services | 2024 |
| 8 Signals Limited | Information & communication | 2009 |
| 8 Victoria Square Management Company Limited | Households | 2004 |
| 80 Percent Nutrition Ltd | Wholesale & retail | 2023 |
| 8020 Consultants North East Ltd | Professional & scientific | 2007 |
| 82 ST. Georges Terrace Limited | Households | 1983 |
| 85WESTGATE Limited | Hospitality | 2025 |
| 888 Electrical Services Ltd | Construction | 2022 |
| 88ALPHABARBERS Ltd | Other services | 2026 |
| 8LEVATE Consulting Ltd | Professional & scientific | 2025 |
| 8LEVATE Ltd | Information & communication | 2025 |
| 8ROX Ltd | Wholesale & retail | 2026 |
| 9 Grosvenor Place Management Company Limited | Households | 2004 |
| 9 Otterburn Terrace Management Limited | Hospitality | 1997 |
| 9-11 Hatherley Road Property Management Limited | Other services | 2025 |
| 92 ST. Georges Terrace Jesmond Management Company Limited | Households | 1991 |
| 922 Capital Ltd | Real estate | 2026 |
| 93 Million Ltd | Information & communication | 2019 |
| 9JADUN Food Hub Limited | Wholesale & retail | 2025 |
| 9T8 Limited | Wholesale & retail | 2023 |
| @Pharmaqp Ltd | Professional & scientific | 2020 |
| A & a Contracts N.E. Ltd | Construction | 2025 |
| A & G Land & Property Agents Limited | Administrative & support | 2021 |
| A & H Housing Limited | Real estate | 2018 |
| A & L Motors North East Ltd | Wholesale & retail | 2019 |
| A & N Cerberus Ltd | Professional & scientific | 2025 |
| A & R Jewellery Limited | Wholesale & retail | 2016 |
| A & SA Properties Limited | Real estate | 2015 |
| A & TP Smile Limited | Health & social care | 2021 |
| A & V Pringle Ltd | Health & social care | 2015 |
| A & Z Properties Investment Ltd | Real estate | 2018 |
| A - Z Stores Limited | Wholesale & retail | 2005 |
| A a and Z Properties Ltd | Real estate | 2022 |