| 21ST Century Productions Limited | Information & communication | 2019 |
| 21ST Century Tanning Ltd | Other services | 2013 |
| 22 Park Place West (Management) Limited | Real estate | 2013 |
| 22, ST. Georges Terrace Limited | Households | 1988 |
| 226 Chillingham RD (Phase 2) Ltd | Real estate | 2024 |
| 226 Chillingham Road Ltd | Real estate | 2021 |
| 23 Inc Group Ltd | Financial services | 2025 |
| 23 Miles Ltd | Financial services | 2012 |
| 23 Osborne Road Limited | Households | 2007 |
| 23 Recruitment Ltd | Education | 2025 |
| 23 to 26 Longwood Close Limited | Households | 2012 |
| 23 Training Ltd | Education | 2025 |
| 230 Westgate Road RTM Company Limited | Real estate | 2006 |
| 24 Hour Plumbing Services Limited | Construction | 2024 |
| 24 West Avenue (Gosforth) Limited | Households | 2001 |
| 24-26 Park Parade Management Company Ltd. | Real estate | 2008 |
| 24-7 Plumbing & Boilers Ltd | Construction | 2025 |
| 24/7 Locksmith Newcastle Ltd | Construction | 2025 |
| 24DIRECT Limited | Wholesale & retail | 2020 |
| 26 Mosley Street Limited | Real estate | 2018 |
| 26 Osborne Road Property Management Co. Limited | Households | 1998 |
| 26-32 (Even Numbers) Jesmond Park Court RTM Company Limited | Households | 2010 |
| 28 Eslington Terrace Management Company Limited | Households | 2000 |
| 2817 Zacfin Ltd | Real estate | 2021 |
| 29 Akenside Terrace (NE2 1TN) Management Company Limited | Real estate | 2019 |
| 29 Akenside Terrace Management Company Limited | Households | 1990 |
| 29-40 Pennyroyal Road RTM Company Limited | Real estate | 2015 |
| 293 Ladbroke Grove Limited | Households | 2017 |
| 2AB Property Management Limited | Real estate | 2023 |
| 2B Communications Ltd | Administrative & support | 2012 |
| 2BOOKAHOLIDAY.COM Limited | Administrative & support | 2005 |
| 2FALZON Limited | Information & communication | 2007 |
| 2KNIVES Bar and Kitchen Ltd | Hospitality | 2018 |
| 2LW Property Ltd | Real estate | 2024 |
| 2M Design Limited | Real estate | 2014 |
| 2PURE Group Limited | Financial services | 2020 |
| 2PURE Products (Distribution) Limited | Manufacturing | 2011 |
| 2PURE Products Limited | Administrative & support | 2009 |
| 3 23 Associates Ltd | Hospitality | 2019 |
| 3 and a Half Ltd | Information & communication | 2025 |
| 3 Granville Road Management Company Limited | Households | 1987 |
| 3 Henshelwood Terrace Limited | Households | 2000 |
| 3 Meldon Terrace Management Company Limited | Extraterritorial | 2009 |
| 3 Phase Enterprise Ltd | Energy | 2025 |
| 3 RXT Ltd | Hospitality | 2022 |
| 3 Steps Project North East Community Interest Company | Hospitality | 2018 |
| 3 Tier Systems UK Limited | Information & communication | 2001 |
| 3 Westfield Avenue Property Management Limited | Households | 2023 |
| 3 WIS UK Limited | Manufacturing | 2023 |
| 30 Grosvenor Place Management Company Limited | Households | 2012 |
| 30 Sanderson Road Limited | Households | 2004 |
| 31 Osborne Road Jesmond Management Ltd | Households | 2020 |
| 31-37 Disbrowe Road Freehold Company Limited | Construction | 2012 |
| 314 Heaton Road Ltd | Real estate | 2025 |
| 3156 Boxing Limited | Administrative & support | 2026 |
| 32 Delaval Road Management Company Limited | Real estate | 2010 |
| 33 Eskdale Terrace Jesmond (Management) Limited | Hospitality | 2004 |
| 342 Enterprises Ltd | Other services | 2019 |
| 35 Albert RD Development Ltd | Construction | 2023 |
| 35 Albert RD Ltd | Real estate | 2023 |
| 35 Heaton Grove Management Company Limited | Real estate | 2005 |
| 35 Station Road Limited | Extraterritorial | 2015 |
| 36 Finborough Road Management Limited | Professional & scientific | 1997 |
| 36 London Road Limited | Health & social care | 2019 |
| 360 a E I Services Ltd | Construction | 2019 |
| 360 GEO Ltd | Professional & scientific | 2021 |
| 360 Growth Partners Limited | Professional & scientific | 2017 |
| 360 OM Limited | Professional & scientific | 2017 |
| 365 Legal Services Ltd | Professional & scientific | 2023 |
| 365 Taxis Limited | Transport & logistics | 2026 |
| 366 LEE High Road Limited | Extraterritorial | 2005 |
| 37 Groat Market Ltd | Hospitality | 2022 |
| 37 ORM Ltd | Real estate | 2025 |
| 374 Durham Road Management Company Limited | Extraterritorial | 2014 |
| 37B Ltd | Hospitality | 2024 |
| 38 Leazes Lane Ltd | Hospitality | 2020 |
| 381 Ward Holdings Ltd | Professional & scientific | 2021 |
| 3842 Osborne Ltd | Real estate | 2016 |
| 38TDG Ltd | Real estate | 2026 |
| 39-49 Wyncote Court RTM Company Limited | Households | 2023 |
| 39B Groat Market Ltd | Hospitality | 2024 |
| 39B1 Ltd | Hospitality | 2024 |
| 39C Ltd | Real estate | 2019 |
| 3D Bio-Tissues Limited | Manufacturing | 2018 |
| 3D Complete Solutions Ltd | Professional & scientific | 2016 |
| 3D Mine Surveying International Limited | Mining & quarrying | 2009 |
| 3EYES Properties Ltd | Hospitality | 2025 |
| 3HD Solutions Limited | Information & communication | 2018 |
| 3K Medical Services Ltd | Health & social care | 2023 |
| 3L Engineering Solutions Ltd | Professional & scientific | 2026 |
| 3L Trade Ltd | Hospitality | 2009 |
| 3ME Properties Ltd | Real estate | 2016 |
| 3ME Residential Properties Ltd | Real estate | 2022 |
| 3R Ainsley Street Limited | Real estate | 2015 |
| 3R Land & Property Ltd | Real estate | 1973 |
| 3R Silver Street Limited | Real estate | 2015 |
| 3S Trading Group Ltd | Administrative & support | 2026 |
| 3SIXTY (North East) Limited | Hospitality | 2022 |
| 3SIXTY Tour Management Ltd | Professional & scientific | 2020 |
| 3T Digital Limited | Information & communication | 2014 |