| Vassallo Motorsport Limited | Arts & recreation | 2015 |
| Vastale Engineering Limited | Wholesale & retail | 1983 |
| Vaten & Boogle Ltd | Financial services | 2025 |
| Vaulkhard Group Limited | Real estate | 1999 |
| Vaulkhard Investment Properties Limited | Real estate | 1994 |
| Vaulkhard Leisure Limited | Hospitality | 2004 |
| Vault 151 Ltd | Wholesale & retail | 2026 |
| Vault Competitions Group Limited | Arts & recreation | 2025 |
| Vaultcomms Ltd | Financial services | 2019 |
| Vauxhall Holiday Park Limited | Hospitality | 1960 |
| VAZ03 Limited | Administrative & support | 2021 |
| Vbfc Ltd | Information & communication | 2023 |
| VD Design Limited | Wholesale & retail | 2023 |
| Vdss Services Ltd | Wholesale & retail | 2025 |
| Vedas Events Ltd | Administrative & support | 2025 |
| Veer Property Management Limited | Real estate | 2019 |
| Vegane Ltd | Hospitality | 2019 |
| Vegano Vegano Limited | Hospitality | 2018 |
| Vegivert Ltd | Professional & scientific | 2024 |
| Vegvisir International Production Industry Specialists Limited | Professional & scientific | 2019 |
| Vehicle Assist (NE) Limited | Wholesale & retail | 2025 |
| Vehicle Movements (North East) Limited | Transport & logistics | 1986 |
| Vela Wealth Limited | Financial services | 2025 |
| Velari Travel Limited | Administrative & support | 2025 |
| Velocity Vehicles Limited | Wholesale & retail | 2023 |
| Velocoach NE Limited | Professional & scientific | 2013 |
| Velora Vapes Ltd | Wholesale & retail | 2026 |
| Veltrex Limited | Information & communication | 2025 |
| Veltrixtech Limited | Information & communication | 2025 |
| Vemury Construction Company Ltd | Construction | 2021 |
| Vemury Structural Consultancy Ltd | Professional & scientific | 2017 |
| Vendsmart Solutions Ltd | Wholesale & retail | 2025 |
| Venkateshwara Foods Ltd | Hospitality | 2025 |
| Venncode Ltd | Information & communication | 2014 |
| Veno Digital Ltd | Education | 2022 |
| Vent Club UK CIC | Health & social care | 2025 |
| Venters Group Limited | Administrative & support | 2022 |
| Ventisei Solutions Ltd | Information & communication | 2025 |
| Ventiyates Breathing Services Limited | Health & social care | 2025 |
| Ventrihouse Limited | Real estate | 2019 |
| Venture 247 Hospitality Ltd | Hospitality | 2026 |
| Venture Enterprises Ltd | Administrative & support | 2019 |
| Venture Fleet Limited | Professional & scientific | 2022 |
| Venture Group Berkshire Ltd | Professional & scientific | 2024 |
| Venture Sunderland CIP LLP | | 2024 |
| Venture Sunderland Fund LP | | 2024 |
| Venture Sunderland GP LLP | | 2024 |
| Venturepace Limited | Households | 1982 |
| Venus Foods NCL Ltd | Hospitality | 2024 |
| Venus Surgical Services Ltd | Health & social care | 2026 |
| Verandern Ltd | Professional & scientific | 2013 |
| Verbena Fine Foods Ltd | Hospitality | 2020 |
| Verdant Maintenance Ltd | Agriculture & fishing | 2026 |
| Verdara Group Limited | Water & waste | 2024 |
| Verismart Newcastle Limited | Real estate | 2021 |
| Verisure Services (UK) Limited | Administrative & support | 2014 |
| Veritas Group Ltd | Construction | 2022 |
| Verne Newsagents Ltd | Wholesale & retail | 2024 |
| Versatile Community Social and Wellbeing Services CIC | Health & social care | 2025 |
| Vertax Accountants Ltd | Professional & scientific | 2019 |
| Vertex Home Solutions Ltd | Construction | 2026 |
| Vertigo Management Limited | Administrative & support | 2006 |
| Very Speedy Relocation Services LLP | | 2023 |
| Vesco ADR Limited | Professional & scientific | 2016 |
| Vespa Restaurant & Bar Ltd | Hospitality | 2024 |
| Vessel Telematics & Systems Ltd | Transport & logistics | 2018 |
| Vesta (General Partner) Limited | Professional & scientific | 2015 |
| Vesta Limited Partnership | | 2015 |
| Vetmedica Instruments Ltd | Professional & scientific | 2025 |
| Vetsetters Ltd | Administrative & support | 2026 |
| VG Digital Solutions Limited | Information & communication | 2026 |
| Vgrb Limited | Health & social care | 2019 |
| VH Vision Limited | Health & social care | 2025 |
| VHV Investments UK Limited | Financial services | 2013 |
| Vi-Vus Properties (NE) Ltd | Real estate | 2022 |
| Viani Stores Ltd | Wholesale & retail | 2020 |
| Viannas Food Ltd | Hospitality | 2019 |
| Viator International Limited | Administrative & support | 2015 |
| Viborna Ltd | Administrative & support | 2025 |
| Vibra Latina Ltd | Other services | 2025 |
| Vibra Latina Newcastle Ltd | Other services | 2025 |
| Vibrant Ventures Limited | Real estate | 2003 |
| Viburnum SW Ltd | Construction | 2019 |
| Vicki Moffat Limited | Administrative & support | 2013 |
| Vicky Brockley Consulting Ltd | Professional & scientific | 2022 |
| Vicky Myers PT Ltd | Arts & recreation | 2015 |
| Vicsmere Ltd | Wholesale & retail | 2026 |
| Victor M. a. Property Limited | Real estate | 2016 |
| Victoria Court (Southport) Limited | Construction | 1995 |
| Victoria Mews (Whickham) Management Company Limited | Real estate | 2003 |
| Victoria Ramez Architecture Ltd | Professional & scientific | 2023 |
| Victoria Square Management Company Limited | Households | 1996 |
| Victory and Innsbruck Limited | Wholesale & retail | 2021 |
| Victory Leisure Limited | Hospitality | 2016 |
| Victory Promotions Limited | Arts & recreation | 2020 |
| Victory Railway Holdings Limited | Professional & scientific | 1996 |
| Vida Property Ltd | Real estate | 2018 |
| Vidan Lawnes Limited | Professional & scientific | 2011 |
| Video Core Ltd | Information & communication | 2026 |
| Video Production News Ltd | Professional & scientific | 2022 |