| Utilitrack (North East) Ltd | Financial services | 2023 |
| Utility Locker Limited | Extraterritorial | 2017 |
| Utility ROV Services (IP) Limited | Administrative & support | 2021 |
| Utility ROV Services Limited | Manufacturing | 2013 |
| Utility Warrant Services Ltd | Other services | 2026 |
| Utilityexperts Limited | Energy | 2024 |
| Utraining Limited | Education | 2018 |
| Uttara Services Ltd | Health & social care | 2019 |
| Uturns Alternative Provision Ltd | Education | 2018 |
| Uvcr Limited | Extraterritorial | 2021 |
| Uventi Heating & Bathrooms Ltd | Construction | 2018 |
| Uzma Akser Coaching and Consulting Limited | Education | 2023 |
| V and N Private Ltd | Wholesale & retail | 2026 |
| V C Corporation Ltd | Transport & logistics | 2011 |
| V K C (NE) Ltd | Hospitality | 2019 |
| V PAK 84 Limited | Hospitality | 2023 |
| V Smart Idea Ltd | Wholesale & retail | 2023 |
| V Tech Services Ltd | Wholesale & retail | 2021 |
| V&N Deatling Ltd | Manufacturing | 2025 |
| V-Easy AI Ltd | Information & communication | 2026 |
| V.M. North Properties Limited | Real estate | 2019 |
| V9 Limited | Other services | 2005 |
| VA Property Developments Limited | Construction | 2015 |
| VA Tech (UK) Pension Scheme Trustee Limited | Financial services | 1998 |
| Vaaradhiinternational Limited | Information & communication | 2020 |
| VAC Systems Limited | Manufacturing | 2002 |
| Vagabond Photography Ltd | Professional & scientific | 2024 |
| VAI VAI Brunch Ltd | Hospitality | 2026 |
| Vald. Birn (UK) Limited | Manufacturing | 1975 |
| Vale Court (Newcastle) Limited | Households | 2001 |
| Vale Woods Ltd | Real estate | 2025 |
| Valero Ltd | Hospitality | 2025 |
| Valeur Consulting Limited | Information & communication | 2023 |
| Valhelen Holdings Ltd | Financial services | 2026 |
| Valhorn Consult Limited | Professional & scientific | 1998 |
| Valiant Investments Ltd | Real estate | 2023 |
| Valiant Property Group Ltd | Real estate | 2023 |
| Valkyrie Strength & Fitness Limited | Health & social care | 2024 |
| Valle Group Limited | Real estate | 2024 |
| Valley Kegs Limited | Wholesale & retail | 2021 |
| Valley View Promotions Limited | Wholesale & retail | 2009 |
| Valliance Ltd | Information & communication | 2024 |
| Vallum Commercial Limited | Administrative & support | 2018 |
| Vallum Farm Limited | Agriculture & fishing | 2018 |
| Vallum Marquees Limited | Hospitality | 2015 |
| Vallum Properties Limited | Real estate | 1994 |
| Vallum Restaurant Limited | Hospitality | 2014 |
| Vallum Wealth Consulting Limited | Professional & scientific | 2022 |
| Valour Multi-Academy Trust | Education | 2017 |
| Valpal Ltd | Real estate | 2017 |
| Valparaiso Arts Ltd | Information & communication | 2020 |
| Value Cars (Teesside) Limited | Wholesale & retail | 2004 |
| Value Centre (Shiremoor) Ltd | Wholesale & retail | 2013 |
| Value Centre (Whitley Bay) Limited | Wholesale & retail | 2019 |
| Value Partnership Group Limited | Professional & scientific | 2015 |
| VALUE4HEALTH Ltd | Public administration | 2019 |
| Vamos Studio Ltd | Information & communication | 2025 |
| Van DEN Bosch Ltd | Information & communication | 2024 |
| Van HEE Transport Limited | Information & communication | 1965 |
| Van Mildert Group Ltd | Financial services | 2020 |
| Vanagelis Media Limited | Professional & scientific | 2025 |
| Vanari Investments Limited | Financial services | 2022 |
| Vanda North East Ltd | Real estate | 2018 |
| Vandrel Capital Ltd | Professional & scientific | 2025 |
| Vane Homes Ltd | Real estate | 2023 |
| Vanessa Bainbridge Ltd | Professional & scientific | 2024 |
| Vanguard CRE Ltd | Real estate | 2026 |
| Vanguard Marine Ltd | Wholesale & retail | 2022 |
| Vanguard Newcastle CIC | Wholesale & retail | 2025 |
| Vanio Drive Ltd | Transport & logistics | 2024 |
| Vankral Services Ltd | Professional & scientific | 2020 |
| Vanp Residential Limited | Real estate | 2022 |
| Vansh Technologies Ltd | Information & communication | 2025 |
| Vansuns Limited | Real estate | 2024 |
| Vantage North Properties Limited | Real estate | 2025 |
| Vantage Procurement Solutions Ltd | Professional & scientific | 2026 |
| Vantage Safety Ltd | Administrative & support | 2011 |
| Vanu Properties Limited | Administrative & support | 2023 |
| VAP Scot 1 Limited | Hospitality | 2020 |
| Vape Drop NE Wholesale Ltd | Wholesale & retail | 2022 |
| Vape N Chill Ltd | Wholesale & retail | 2023 |
| Vapey Shakey Ltd | Wholesale & retail | 2026 |
| Vapor Bliss Ltd | Wholesale & retail | 2025 |
| Varahi NE Limited | Health & social care | 2019 |
| Vardy 1985 Investments Limited | Professional & scientific | 2013 |
| Vardy Family Office Limited | Professional & scientific | 1999 |
| Vardy Property (Teesside) Limited | Real estate | 2006 |
| Vardy Property Aberdeen Ltd | Real estate | 2005 |
| Vardy Property Group Limited | Real estate | 2002 |
| Vardy Ventures Ltd | Real estate | 2005 |
| Varg Limited | Professional & scientific | 2008 |
| Vargr Virtual Limited | Arts & recreation | 2024 |
| Various Marketing Limited | Professional & scientific | 2005 |
| Varis LUX Ltd | Wholesale & retail | 2025 |
| Varma Holdings Ltd | Other services | 2020 |
| Varndio Limited | Wholesale & retail | 1983 |
| Varsity Briganti Limited | Real estate | 2026 |
| Varughese Associates Ltd | Health & social care | 2017 |
| Vascraft Estates Ltd | Real estate | 2025 |
| Vasp Holdings Ltd | Households | 2019 |