| Sheeps END Limited | Other services | 2014 |
| Sheer Quality LAL Ltd | Hospitality | 2020 |
| Sheet Metal Products (Newcastle) Ltd | Manufacturing | 2014 |
| Sheffield Property Limited | Information & communication | 2013 |
| Shek Digital Ltd | Information & communication | 2025 |
| Shellbraes Property Ltd | Real estate | 2014 |
| Shellfish Express Limited | Wholesale & retail | 2010 |
| Shenfine Ltd | Health & social care | 2018 |
| Shenton Creative Ltd | Information & communication | 2007 |
| Shepherd COX Hotels (Lymm) Limited | Hospitality | 2015 |
| Shepherd Offshore Engineering Limited | Manufacturing | 1968 |
| Shepherd Offshore Group Limited | Real estate | 2007 |
| Shepherd Offshore Limited | Real estate | 1946 |
| Shepherd Offshore Services Limited | Real estate | 1970 |
| Shepherds Quay Management Company Limited | Households | 2021 |
| Shepherds Waste Management Ltd | Water & waste | 2024 |
| Sheraton Park Residents Management Company Limited | Construction | 2016 |
| Sherburn House Charity | Other services | 2018 |
| Sheriezade Collection Limited | Wholesale & retail | 2020 |
| Sheriffs Place Limited | Construction | 2022 |
| Shero Group Ltd | Information & communication | 2026 |
| Shersoft Ltd | Information & communication | 2020 |
| SHF Medical Limited | Administrative & support | 2014 |
| Shield Electrical Systems Ltd | Construction | 2025 |
| Shield Ventilation Systems Ltd | Manufacturing | 2014 |
| Shields Bargains Ltd | Wholesale & retail | 2019 |
| Shields Construction Ltd | Construction | 2025 |
| Shields Road Barber Limited | Other services | 2014 |
| Shiells Lockwood Shiells Electrical Limited | Construction | 2009 |
| Shift AI Ltd | Information & communication | 2026 |
| Shikara Whitley Limited | Hospitality | 2019 |
| Shina Collins Studios Limited | Manufacturing | 2025 |
| Shine and Companionship Ltd | Public administration | 2025 |
| Shine on Community Launderette CIC | Other services | 2024 |
| Shinevision Ltd | Information & communication | 2009 |
| Shining Light Publications Limited | Information & communication | 2022 |
| Ship Ouseburn Limited | Hospitality | 2015 |
| Shipaid Diesel Services Limited | Manufacturing | 2016 |
| Shipcote Furniture Limited | Wholesale & retail | 2013 |
| Shipyrd.Ai Ltd | Information & communication | 2026 |
| Shiremoor Amatuer Boxing Club CIC | Arts & recreation | 2025 |
| Shiremoor Car Wash Ltd | Wholesale & retail | 2026 |
| Shiremoor Carpet Centre Limited | Construction | 1995 |
| Shiremoor Cars & Commercial Limited | Wholesale & retail | 2024 |
| Shiremoor Diner Limited | Hospitality | 2019 |
| Shiremoor MOT Centre Ltd | Wholesale & retail | 2015 |
| Shiremoor Motor Company Ltd | Wholesale & retail | 2021 |
| Shirtprint Ltd | Manufacturing | 2024 |
| Shisha Fest Limited | Wholesale & retail | 2022 |
| Shisha House NCL Ltd | Wholesale & retail | 2024 |
| Shiv Shakti Property Group Limited | Real estate | 2025 |
| Shivji Properties Ltd | Real estate | 2020 |
| Shld Sports Ltd | Wholesale & retail | 2025 |
| Shnl (051) Limited | Hospitality | 2023 |
| Shnl (061) Limited | Hospitality | 2023 |
| Shnl (071) Limited | Hospitality | 2023 |
| Shnl (081) Limited | Hospitality | 2023 |
| Shnl (091) Limited | Hospitality | 2021 |
| Shnl (101) Limited | Hospitality | 2023 |
| Shnl (121) Limited | Hospitality | 2023 |
| Shnl (131) Limited | Hospitality | 2023 |
| Shnl (151) Limited | Hospitality | 2023 |
| Shnl (161) Limited | Hospitality | 2023 |
| Shnl (171) Limited | Hospitality | 2023 |
| Shnl (191) Limited | Hospitality | 2023 |
| Shnl (201) Limited | Hospitality | 2014 |
| Shnl (211) Limited | Hospitality | 2023 |
| Shnl (221) Limited | Hospitality | 2023 |
| Shnl (231) Limited | Hospitality | 2015 |
| Shnl (241) Limited | Hospitality | 2015 |
| Shnl (251) Limited | Hospitality | 2023 |
| Shnl (261) Limited | Hospitality | 2021 |
| Shnl (271) Limited | Hospitality | 2021 |
| Shnl (301) Limited | Hospitality | 2021 |
| Shnl (331) Limited | Hospitality | 2023 |
| Shnl (341) Limited | Hospitality | 2023 |
| Shnl (CS) Limited | Administrative & support | 2023 |
| Shnl (Holdco 1) Limited | Financial services | 2023 |
| Shnl (Holdco 2) Limited | Financial services | 2023 |
| Shnl (PC1) Limited | Financial services | 2017 |
| Shnl (PC2) Limited | Financial services | 2017 |
| Shnl (PC3) Limited | Real estate | 2023 |
| Shoal Properties Limited | Real estate | 2005 |
| Shoe & Laundry Wash Co Ltd | Other services | 2026 |
| Shoe Lace Capital and Investments (FH) Limited | Real estate | 2024 |
| Shollytem Ltd | Professional & scientific | 2013 |
| Shonelly Engineering Limited | Administrative & support | 2012 |
| Shoo 644 Limited | Extraterritorial | 2020 |
| Shop Genius Store Limited | Wholesale & retail | 2024 |
| Shop Local Adelaide Limited | Wholesale & retail | 2025 |
| Shop Number Nine Ltd | Wholesale & retail | 2022 |
| Shopello Ltd | Wholesale & retail | 2025 |
| Shoppypop Ltd | Wholesale & retail | 2025 |
| Shoptimised Group Limited | Financial services | 2024 |
| Shoptimised Ltd | Information & communication | 2018 |
| Shore Real Estate Limited | Construction | 2016 |
| Shoreline Fibre Services Ltd | Information & communication | 2022 |
| Short Stays Away Ltd | Hospitality | 2018 |
| Short Stays Newcastle Ltd | Hospitality | 2025 |
| Shorza Ltd | Other services | 2024 |