| Rosie Harris Ltd | Real estate | 2015 |
| Rosies Place Dog Daycare Ltd | Professional & scientific | 2018 |
| Rosina Homes Ltd | Real estate | 2023 |
| Roskai Limited | Wholesale & retail | 2019 |
| Ross & WES Bar Split & Consultancy Service Ltd | Professional & scientific | 2023 |
| Ross Buttigieg Ltd | Transport & logistics | 2016 |
| Ross Elliott Surveying Limited | Professional & scientific | 2007 |
| Ross Mepstead Logistics Ltd | Transport & logistics | 2025 |
| Ross Pringle Inspections Ltd | Professional & scientific | 2019 |
| Rotary Machine Tool Co.Limited(The) | Manufacturing | 1968 |
| Rotary Power Ltd. | Manufacturing | 1968 |
| Rotation Finance Limited | Financial services | 1986 |
| Roth Properties LLP | | 2010 |
| Rothbury Cottage Care Ltd | Health & social care | 2022 |
| Rothko Limited | Arts & recreation | 1993 |
| Rothko Properties Limited | Real estate | 2002 |
| Rothley Park Investments Limited | Real estate | 2002 |
| Rothley Residential Limited | Real estate | 2020 |
| Rothwell & Robertson Limited | Extraterritorial | 1976 |
| Rothwell Advisory Ltd | Information & communication | 2025 |
| Rouf & Rizwana & Sons Ltd | Hospitality | 2018 |
| Round Sun Limited | Information & communication | 2004 |
| Roundhill Property Investments Ltd | Real estate | 2021 |
| Route 72 Cafe Ltd | Hospitality | 2024 |
| Route 72 Coffee & Kitchen Ltd | Hospitality | 2026 |
| Route Xpress Ltd | Hospitality | 2018 |
| Routledge Residential Ltd | Real estate | 2022 |
| Routledges the Bakers Limited | Manufacturing | 2002 |
| Rovin Group Holdings Limited | Professional & scientific | 2025 |
| ROW and Scott Limited | Professional & scientific | 2010 |
| Row-Mech (Mechanical Building Services Engineers Northern Region) Limited | Construction | 2025 |
| Rowan Court (Newcastle) Management Company Limited | Households | 1996 |
| Rowan Media Group Limited | Information & communication | 2020 |
| Rowe GXP Ltd | Professional & scientific | 2019 |
| Rowe Property Limited | Real estate | 2018 |
| Rowells (1924) Limited | | 1924 |
| ROX Media Limited | Professional & scientific | 2026 |
| Roxcare Ltd | Health & social care | 2017 |
| Roxid Ltd | Information & communication | 2023 |
| Roxxal Ltd | Manufacturing | 2024 |
| Roxy Cleaning AS Limited | Administrative & support | 2025 |
| ROY4LE Ltd | Wholesale & retail | 2026 |
| Roya Roya Ltd | Wholesale & retail | 2025 |
| Royal IHC Limited | Manufacturing | 1997 |
| Royale Gifts Limited | Wholesale & retail | 2021 |
| Royale Meat Limited | Wholesale & retail | 2024 |
| Royel Security Ltd | Other services | 2010 |
| Royston Vale Limited | Real estate | 2023 |
| Rozzy Pro Services Limited | Administrative & support | 2025 |
| RP 365 Ltd | Real estate | 2020 |
| Rpav Limited | Real estate | 2011 |
| RPH Access Ltd | Manufacturing | 2023 |
| RPM Music Newcastle Ltd | Wholesale & retail | 2025 |
| RPM Tuning Group Ltd | Wholesale & retail | 2019 |
| Rprsnt.Uk Sales Ltd | Professional & scientific | 2025 |
| RPU Group Limited | Construction | 1960 |
| RQ Hanlin Ltd | Real estate | 2022 |
| RR IT Consultants ( PVT) Limited | Information & communication | 2018 |
| RR Projects Limited | Construction | 2019 |
| RR Property Holdings Ltd | Real estate | 2026 |
| Rr&Mw Ltd | Real estate | 2013 |
| Rrbc Solutions Limited | Real estate | 2024 |
| RRNT4 Limited | Households | 2020 |
| RRNT7 Ltd | Wholesale & retail | 2024 |
| RRNT8 Ltd | Hospitality | 2022 |
| RRNT9 Limited | Wholesale & retail | 2020 |
| Rrscaffholdingn.E Limited | Construction | 2025 |
| Rrscott Homes Limited | Real estate | 2025 |
| RS Barberz Ltd | Other services | 2024 |
| RS Foods NE Ltd | Hospitality | 2025 |
| RS Land & Property Ltd | Other services | 2019 |
| RS Masonry Ltd | Construction | 2024 |
| RS Mortgages NE Ltd | Financial services | 2017 |
| RS Roof Solutions Limited | Construction | 2025 |
| RS Security & FM Ltd | Construction | 2024 |
| RS Services (Newcastle) Ltd | Construction | 2017 |
| RS185 Investments Limited | Real estate | 2026 |
| Rsafoods Ltd | Wholesale & retail | 2026 |
| RSC Land & Property Ltd | Real estate | 2019 |
| RSL Electrical Solutions Ltd | Construction | 2024 |
| RSL NE Limited | Mining & quarrying | 2016 |
| Rspi Limited | Real estate | 2024 |
| RSR Capital Ventures Ltd | Other services | 2023 |
| RSR Hospitality SF Ltd | Hospitality | 2026 |
| RST Prints Ltd | Manufacturing | 2024 |
| RST Wholesale Ltd | Wholesale & retail | 2021 |
| Rstpi Ltd | Real estate | 2022 |
| RT Aesthetics Ltd | Other services | 2018 |
| RT Healthcare Limited | Public administration | 2020 |
| RT Staffing Ltd | Health & social care | 2018 |
| RT Technical Consultancy Ltd | Professional & scientific | 2015 |
| RTC Property Developments Ltd | Real estate | 2025 |
| RTC Retail Limited | Professional & scientific | 2016 |
| RTC Sports | Arts & recreation | 2006 |
| RTH Foods BB1 Ltd | Wholesale & retail | 2022 |
| RTH R to Home Ltd | Real estate | 2025 |
| RTM North East Limited | Administrative & support | 2012 |
| Rtts (Recovery and Treatment Services) Holdings Ltd | Financial services | 2014 |
| RTW Property Surveys Ltd | Administrative & support | 2026 |
| Rtxns Limited | Professional & scientific | 2023 |