| Righi Limited | Construction | 2020 |
| Righi Property Developments Limited | Construction | 2020 |
| RIJ Golf Events and Services Ltd | Arts & recreation | 2026 |
| Rilade Investments Ltd | Professional & scientific | 2021 |
| Rising High Development and Construction Consultancy Ltd | Construction | 2013 |
| Risk and Management Services Limited | Professional & scientific | 2012 |
| Rithu Arts Ltd | Education | 2025 |
| Rjdshop Ltd | Manufacturing | 2026 |
| RK Racing Ltd | Arts & recreation | 2024 |
| RM & K Whittaker Poultry Ltd | Agriculture & fishing | 2012 |
| RMZ Entertainment Limited | Arts & recreation | 2025 |
| RO Engineeria Ltd | Professional & scientific | 2019 |
| Roach's Roaster Limited | Hospitality | 2009 |
| ROB Durham Holdings Ltd | Financial services | 2025 |
| Robin Siddorn Limited | Construction | 2003 |
| Rock Garden Cycles Ltd | Wholesale & retail | 2014 |
| Rockmate Limited | Mining & quarrying | 1998 |
| Roea Limited | Wholesale & retail | 2025 |
| Rogan Electrical Services Limited | Construction | 2021 |
| ROI Automotive Ltd | Extraterritorial | 2025 |
| Roll the Bones Limited | Hospitality | 2024 |
| Romazzino Limited | Hospitality | 2007 |
| Rome Developments Limited | Manufacturing | 2018 |
| RON Darch & Sons Co Ltd | Extraterritorial | 1983 |
| ROOF4U Property Management Limited | Real estate | 2023 |
| Rookery Equine Limited | Administrative & support | 2018 |
| Room 11 Ltd | Professional & scientific | 2024 |
| Rope Lane Management Limited | Households | 2013 |
| Roscoe Regeneration Limited | Construction | 2024 |
| Rose Bridge Enterprise Ltd | Real estate | 2024 |
| Rose Farm Barns Management Company Limited | Water & waste | 2005 |
| Roselevaa Ltd | Information & communication | 2025 |
| Rosie's Beauty Limited | Other services | 2021 |
| Rothy Group Ltd | Wholesale & retail | 2024 |
| Rover on Ltd | Professional & scientific | 2017 |
| Rowland Coaching Ltd | Education | 2022 |
| Rowlands Healthcare Limited | Health & social care | 2019 |
| Rowlinson Consolidated Ltd | Professional & scientific | 2015 |
| Rowlinson Garden Products Limited | Manufacturing | 1946 |
| Rowlinson Group Limited | Real estate | 1961 |
| Rowlinson Packaging Limited | Manufacturing | 1974 |
| Rowlinson Timber Limited | Extraterritorial | 1946 |
| RP Medics Limited | Health & social care | 2021 |
| RP Properties Midlands Limited | Real estate | 2022 |
| RS Ghigo Limited | Manufacturing | 2022 |
| Rsco Actuarial Ltd | Financial services | 2023 |
| RSG Concepts Ltd | Households | 2025 |
| RSG Entrance Solutions Ltd | Manufacturing | 2026 |
| RTC Accommodation Limited | Real estate | 2023 |
| RTL Contracting Limited | Professional & scientific | 2015 |
| Ruci Ltd | Wholesale & retail | 2022 |
| Rufloreo Stays Ltd | Hospitality | 2023 |
| Ruiseart Rock Limited | Professional & scientific | 2024 |
| Rumen Supplies Ltd | Wholesale & retail | 2017 |
| Runners Relief Limited | Manufacturing | 2021 |
| Rupa Lettings Ltd | Real estate | 2021 |
| Rural Church Schools Academy Trust | Education | 2017 |
| Rushton Ventures Limited | Administrative & support | 2016 |
| RVE Consulting Limited | Information & communication | 2025 |
| RWR Property Co Ltd | Construction | 2025 |
| Ryder Rope Access Ltd | Professional & scientific | 2024 |
| Ryley Properties Ltd | Real estate | 2021 |
| Rylstone Consulting Associates Limited | Professional & scientific | 2022 |
| S & M Chantler Investments Limited | Financial services | 2016 |
| S & M Chantler Trading Limited | Financial services | 2017 |
| S a Global Holdings Limited | Financial services | 2024 |
| S a Talents Ltd | Administrative & support | 2025 |
| S Heath Property Developers Ltd | Real estate | 2026 |
| S J Bell Consulting Limited | Professional & scientific | 2017 |
| S.M. Consultancy Cheshire Limited | Professional & scientific | 2008 |
| SA Communications Limited | Professional & scientific | 2016 |
| SA Community Ltd | Education | 2024 |
| Safe Haven SC Limited | Health & social care | 2017 |
| Safetycore Limited | Information & communication | 2026 |
| Sage Chiropractic Ltd | Health & social care | 2024 |
| Sahara Management Solutions Limited | Professional & scientific | 2018 |
| Sales Fraction Co Ltd | Professional & scientific | 2025 |
| Salford Stockport and Trafford Local Medical Committee Limited | Other services | 2022 |
| Salon Forty Eight Limited | Other services | 2011 |
| Salon VIE Hairdressing Limited | Other services | 2003 |
| SAM Stafford Ltd | Administrative & support | 2019 |
| Samantha Rudd Limited | Arts & recreation | 2020 |
| Sandfield Securities Limited | Real estate | 1971 |
| Sandongate Limited | Professional & scientific | 2018 |
| Sandown Reach Limited | Real estate | 2002 |
| Sandrey Properties Limited | Real estate | 2015 |
| Sandstone Wealth Management Ltd | Financial services | 2025 |
| Sanguine European Limited | Wholesale & retail | 2017 |
| Sapphire Living Care Ltd | Real estate | 2024 |
| SAR Consultant Solutions Limited | Professional & scientific | 2010 |
| Sara Triebler Ltd | Professional & scientific | 2016 |
| Sarah's Shoes Limited | Wholesale & retail | 2015 |
| Sassy Number Plates Limited | Administrative & support | 2010 |
| Saxons Business Services Limited | Professional & scientific | 2005 |
| SC Autos Nantwich Ltd | Wholesale & retail | 2025 |
| SC Office Supplies Limited | Wholesale & retail | 2015 |
| Scanlans Holdings Limited | Professional & scientific | 2006 |
| Scimitar Group Limited | Professional & scientific | 2021 |
| Sclcarwash Ltd | Administrative & support | 2025 |
| Score Worldwide Limited | Extraterritorial | 2018 |