| SGM Joiners Ltd. | Construction | 2004 |
| SGW Property Solutions Ltd. | Administrative & support | 2005 |
| Shadow Haus Ltd | Wholesale & retail | 2024 |
| Shaeroo Ltd | Real estate | 2023 |
| Shah Medics Limited | Health & social care | 2023 |
| Shainingelectrical Limited | Construction | 2014 |
| Sharaz & Co Ltd | Wholesale & retail | 2016 |
| Sharp Print and Design Ltd | Wholesale & retail | 2023 |
| Sharp Property Investments Scotland Ltd | Real estate | 2023 |
| SHC Traders Ltd | Wholesale & retail | 2015 |
| Shear Class Plumbing & Heating Ltd | Construction | 2021 |
| Sheerazii Ltd | Wholesale & retail | 2025 |
| Shelley Mckeand Ltd | Transport & logistics | 2025 |
| Sheperd Limited | Information & communication | 2011 |
| Shepka Productions Ltd | Information & communication | 2022 |
| Shiloh Properties (Scotland) Limited | Real estate | 2024 |
| Shoeshine Music Ltd. | Information & communication | 2019 |
| Shopetra UK Ltd | Wholesale & retail | 2026 |
| Shopping Moon Ltd | Wholesale & retail | 2022 |
| Shotts GAS Ltd | Manufacturing | 2012 |
| Shotts VET Ltd | Professional & scientific | 2016 |
| Shoulder Buddies Ltd | Wholesale & retail | 2025 |
| Shrabs Ltd | Health & social care | 2024 |
| Shsmma Limited | Arts & recreation | 2021 |
| Siddique Consultancy Private Limited | Information & communication | 2015 |
| Siete Ocho Nueve Limited | Hospitality | 2022 |
| SIF Electrical Ltd | Construction | 2021 |
| Siframe Property Ltd | Real estate | 2023 |
| SIG Scots Co Limited | Administrative & support | 2018 |
| Signature by Shama Limited | Financial services | 2019 |
| Signature CCA Limited | Professional & scientific | 2013 |
| Signstreambsl Ltd | Professional & scientific | 2026 |
| Silver Apples of the Moon Ltd | Other services | 2022 |
| Silverbanks Limited | Wholesale & retail | 2023 |
| Silverhound Ltd | Professional & scientific | 2016 |
| Silverton Maintenance Limited | Manufacturing | 2014 |
| Simple Waste Solutions Limited | Water & waste | 2010 |
| Simply Interiors Ltd | Administrative & support | 2010 |
| Simply R & D Ltd | Professional & scientific | 2021 |
| Simply Sweet Events Co. Ltd | Hospitality | 2026 |
| Simpson Physiotherapy Ltd | Other services | 2020 |
| Sims Foundry Technologies Ltd | Wholesale & retail | 2006 |
| Sincere Stationery Limited | Administrative & support | 2009 |
| Sinclair Storage Ltd | Transport & logistics | 2020 |
| Sinclairexpressparcels Limited | Financial services | 2025 |
| Sinky Tyre Wholesale Ltd | Wholesale & retail | 2022 |
| Sivan Ltd | Administrative & support | 2019 |
| SJ Compliance Solutions Ltd | Professional & scientific | 2025 |
| SJ Contract Solutions Ltd | Professional & scientific | 2019 |
| SJ Deli Ltd | Hospitality | 2026 |
| SJ Pro Ltd | Wholesale & retail | 2019 |
| SJ Property Lets Limited | Real estate | 2024 |
| SJD Hair Ltd | Other services | 2015 |
| Sjgh Transport Ltd | Transport & logistics | 2026 |
| Sjlinnovations Limited | Professional & scientific | 2021 |
| SJW Property Group Ltd | Construction | 2026 |
| SK LOW Consulting Ltd | Information & communication | 2020 |
| Sked Construction Limited | Construction | 2002 |
| Skemma Ltd | Arts & recreation | 2023 |
| Skiffington GAS and Plumbing Services Ltd | Construction | 2021 |
| Skmf Limited | Other services | 2023 |
| SKYE6 Ltd | Administrative & support | 2024 |
| Skyforth Limited | Hospitality | 2000 |
| Skyhorse Oriental Food Supplies Ltd | Hospitality | 2016 |
| SL (UK) Limited | Other services | 2008 |
| Slava Group Limited | Hospitality | 2024 |
| Sleepy Valley (Scotland) Limited | Wholesale & retail | 2010 |
| Sliverline Consultancy Ltd | Professional & scientific | 2026 |
| SLO COG Ltd | Other services | 2023 |
| Sloan Dental Carfin Ltd | Health & social care | 2021 |
| SM Lifting Ltd | Wholesale & retail | 2021 |
| Smarca Ltd | Wholesale & retail | 2026 |
| Smart Family Homes Ltd | Real estate | 2023 |
| Smart Pizza Ltd | Hospitality | 2025 |
| Smartways Foods Limited | Hospitality | 2014 |
| Smiths Apartments Ltd | Real estate | 2022 |
| Smiths Hotel Ltd | Financial services | 2003 |
| SMK33 Limited | Wholesale & retail | 2025 |
| Smoke Vapes Ltd | Wholesale & retail | 2025 |
| SMR Specialist Services Ltd | Manufacturing | 2011 |
| Smsworld Ltd | Professional & scientific | 2025 |
| SN Project Services Limited | Administrative & support | 2019 |
| Snackshack Vending Ltd | Wholesale & retail | 2023 |
| Snaq Catering Ltd | Hospitality | 2022 |
| Snowdon Apartments Limited | Hospitality | 2026 |
| SO False Ltd | Wholesale & retail | 2023 |
| SO Irvine Properties Limited | Households | 2019 |
| Soccer Stars Academy Carlisle & Cumbria Ltd | Arts & recreation | 2021 |
| Soccer Stars Academy Dumfries & Galloway Ltd | Arts & recreation | 2025 |
| Soccer Stars Academy East Dunbartonshire Limited | Arts & recreation | 2024 |
| Soccer Stars Academy Glasgow Ltd | Arts & recreation | 2021 |
| Soccer Stars Academy Renfrew Ltd | Arts & recreation | 2022 |
| Sodick Services Ltd | Transport & logistics | 2025 |
| SOF Properties Scotland Ltd | Real estate | 2024 |
| Solar United Ltd | Manufacturing | 2021 |
| Solidtrack Logistics Ltd | Transport & logistics | 2025 |
| Sophia Facades Ltd | Construction | 2025 |
| Sora LC Ltd | Other services | 2026 |
| Sosho Limited | Manufacturing | 2026 |
| Soundsational Community Music Limited | Arts & recreation | 2012 |