| Clwydian Ltd | Hospitality | 2022 |
| CMS UK Holdings Limited | Information & communication | 2021 |
| Coastal Cladding Limited | Construction | 2013 |
| Coastline Cladding Ltd | Construction | 2016 |
| Coating Plant Ltd | Other services | 2025 |
| Cobweb Electrical Consulting Limited | Professional & scientific | 2026 |
| Coed Maes-Mynan Estates Limited | Hospitality | 1963 |
| COFFEE28 Limited | Hospitality | 2024 |
| Collingwood & SON Chimneys Ltd | Construction | 2025 |
| Community Clubhouse and Gardens Ltd | Health & social care | 2005 |
| Connah Draughting Ltd | Information & communication | 2025 |
| Connecting NOW (UK) Ltd | Professional & scientific | 2024 |
| Connecting NOW Group Limited | Financial services | 2025 |
| Conservation Digital | Information & communication | 2023 |
| Consultancy Conveyancing Ltd | Professional & scientific | 2025 |
| Conway Courier Services Ltd | Transport & logistics | 2020 |
| Cooks Holdings Mold Ltd | Financial services | 2025 |
| Cooks Properties (Mold) Ltd | Real estate | 2025 |
| Core Impact Group C.I.C. | Professional & scientific | 2024 |
| Country House Childcare Limited | Health & social care | 2026 |
| Coveira Limited | Real estate | 2015 |
| Cowen-Wright Consultants Limited | Professional & scientific | 2021 |
| CP Landscapes Ltd | Administrative & support | 2016 |
| CPS Monitoring Limited | Administrative & support | 1997 |
| Craig Hughes Plumbing and Heating Ltd | Construction | 2025 |
| Craig Massey Builders Ltd | Construction | 2007 |
| Craig Tree Services Limited | Agriculture & fishing | 2015 |
| Cravin UK Limited | Wholesale & retail | 2025 |
| Crcr Limited | Professional & scientific | 2014 |
| Cresta Cars Private Hire Limited | Transport & logistics | 2021 |
| Crime Prevention Services Group Limited | Administrative & support | 2006 |
| Crime Prevention Services Holdings Limited | Financial services | 2019 |
| Crime Prevention Services Limited | Administrative & support | 1984 |
| Croston Developments Limited | Construction | 2015 |
| Croston Homes Ltd | Construction | 2020 |
| CS Transform Limited | Professional & scientific | 2009 |
| CT Electrical Limited | Construction | 2024 |
| Culinary Affairs Catering Ltd | Hospitality | 2024 |
| Curious Cats Learning Ltd | Professional & scientific | 2025 |
| Customer Touch Point Limited | Professional & scientific | 2016 |
| Cutshorts Ltd | Information & communication | 2026 |
| CW Joinery and Construction Ltd | Construction | 2026 |
| Cwmni Hydro Dwrnudon CYF | Energy | 2015 |
| Cyber Nexus Holding Limited | Financial services | 2025 |
| Cânsing Ltd | Education | 2016 |
| D & B Management Consultants Limited | Administrative & support | 2009 |
| D & N Doherty & SON Builders Ltd | Construction | 2021 |
| D & S Motors Limited | Wholesale & retail | 2008 |
| D a Hughes Electrical Limited | Construction | 2012 |
| D G Hicks Ltd | Professional & scientific | 2013 |
| D G Jones Heating Ltd | Manufacturing | 2011 |
| D G Roberts Haulage Ltd | Transport & logistics | 2019 |
| D H Jones Limited | Manufacturing | 2002 |
| D I H Groundworks Ltd | Construction | 2018 |
| D J Read Haulage Limited | Transport & logistics | 2021 |
| D J Services (Wales) Limited | Extraterritorial | 2002 |
| D Matthews & Daughters Ltd | Construction | 2023 |
| D P Developments North West Ltd | Construction | 2018 |
| D P Williams Group Limited | Mining & quarrying | 2014 |
| D P Williams Quarries Limited | Mining & quarrying | 2019 |
| D Williams Groundworks Ltd | Construction | 2019 |
| D.R. Plumbing & Heating Ltd | Construction | 2019 |
| D.R.Holdings (Wrexham) Ltd | Real estate | 2016 |
| Damitt Events Ltd | Information & communication | 2024 |
| Daniel Ellson Ltd | Construction | 2019 |
| Daniel Owen Community Association | Administrative & support | 1994 |
| Danosh Services Ltd | Professional & scientific | 2007 |
| Data Properties Limited | Construction | 2003 |
| Data Track Process Instruments Limited | Manufacturing | 1993 |
| Data Track Technology Limited | Information & communication | 1979 |
| Davies Homes (N.W.) Limited | Construction | 1999 |
| Daydot Entertainment Ltd | Information & communication | 2025 |
| Daytona Motorsport 1997 Ltd | Wholesale & retail | 2026 |
| DE Prez Training Limited | Professional & scientific | 2018 |
| Decision Archetype Limited | Information & communication | 2021 |
| DED Accountancy Services Ltd | Professional & scientific | 2020 |
| DEE Civil Engineering Limited | Construction | 1969 |
| DEE Valley Roofing Limited | Construction | 2023 |
| Deeps Entertainment Ltd | Information & communication | 2021 |
| Delphinus Properties LLP | | 2015 |
| Delta Connection Electrical Ltd | Manufacturing | 2021 |
| Delyn Safety UK Limited | Professional & scientific | 2013 |
| Denary Ltd | Financial services | 2024 |
| Dentsorted Ltd | Wholesale & retail | 2022 |
| Denvi Cleaning Services Ltd | Administrative & support | 2026 |
| Derwen Information Technology Limited | Information & communication | 2006 |
| Derwen Properties Ltd | Real estate | 1995 |
| Development by Freemans Ltd | Construction | 2011 |
| DF Moore Contracting Limited | Information & communication | 2017 |
| DG Medical Limited | Health & social care | 2015 |
| DG Power Consultancy Ltd | Administrative & support | 2024 |
| DG Pure Homes Ltd | Administrative & support | 2025 |
| DGR Development Projects Limited | Real estate | 2026 |
| Dhenin Ltd | Wholesale & retail | 2024 |
| Dickens of Wrexham Limited | Wholesale & retail | 1987 |
| Digishift Limited | Information & communication | 2018 |
| Digital Marketing and PR Limited | Professional & scientific | 2009 |
| DIJ Management Information Services Limited | Professional & scientific | 2022 |
| Diligent Digital Limited | Information & communication | 2021 |
| Dirtbag Entertainment Ltd | Administrative & support | 2024 |