| Robert Lewandowski Refurbishment Ltd | Construction | 2024 |
| Robinas Group Ltd | Real estate | 2018 |
| Robore Cuts Limited | Construction | 1992 |
| Robore Holdings 2022 Ltd | Financial services | 2022 |
| Robotics Automation and Workflow (RAW) Ltd | Information & communication | 2024 |
| Robted Ltd | Construction | 2026 |
| Rocco DEA Ltd | Hospitality | 2024 |
| Rocha Property Management Ltd | Households | 2025 |
| Rocket Project Productions Limited | Arts & recreation | 2023 |
| ROI Marketers Ltd | Financial services | 2021 |
| Romeoville Construction UK Ltd | Construction | 2022 |
| Romeoville Properties UK Limited | Real estate | 2015 |
| Romlyn Freehold Limited | Real estate | 2016 |
| Rooster Zone 4U Ltd | Hospitality | 2020 |
| ROR Couriers Limited | Transport & logistics | 2025 |
| Rora Couriers Limited | Transport & logistics | 2025 |
| Rosetta Luxury Stays Ltd | Hospitality | 2026 |
| Rospuda Building Limited | Construction | 2021 |
| Rotorpix Ltd | Professional & scientific | 2022 |
| Roxet Ltd | Wholesale & retail | 2020 |
| Royalty Care Consultancy Ltd | Health & social care | 2020 |
| Royce 01 Limited | Wholesale & retail | 2024 |
| Royce 02 Limited | Wholesale & retail | 2025 |
| Royce-Hall Building Services Ltd | Construction | 2020 |
| Rozelle Lodge Limited | Households | 1991 |
| Rozran Sports Limited | Wholesale & retail | 2025 |
| RP Building Limited | Construction | 2007 |
| Rrnvithu Ltd | Health & social care | 2024 |
| RSL Business Solutions Ltd | Other services | 2015 |
| Ruby IT Solutions Limited | Information & communication | 2019 |
| Rudaba Holding Ltd | Real estate | 2024 |
| Rudri Ecom Limited | Wholesale & retail | 2025 |
| Ruiz Galan Studio Ltd | Professional & scientific | 2024 |
| Rumbold Investments Limited | Extraterritorial | 1958 |
| Rumbold Securities Limited | Extraterritorial | 1973 |
| Run-Time Group Ltd | Information & communication | 2023 |
| Rupert & Rupella Ltd | Information & communication | 2023 |
| Russell Hewes Limited | Construction | 2016 |
| Russell Hewes Studios Ltd | Arts & recreation | 2022 |
| RYE Express Limited | Wholesale & retail | 2012 |
| Ryntr Ltd | Real estate | 2025 |
| Ré-Luxe Beauty Ltd | Other services | 2025 |
| S Ayngaran Ltd | Wholesale & retail | 2024 |
| S Bismillah Investment 2 Ltd | Real estate | 2025 |
| S Bismillah Investment Ltd | Real estate | 2023 |
| S H Builder Ltd | Construction | 2009 |
| S P Homes Limited | Health & social care | 2004 |
| S Yanev Ltd | Construction | 2023 |
| S&B Painting Decorating Ltd | Construction | 2021 |
| S&K Traders Ltd | Wholesale & retail | 2018 |
| S&N Limited | Administrative & support | 2019 |
| S&S Matters Ltd | Health & social care | 2017 |
| S.Cheveron Ltd | Real estate | 2012 |
| S.F. & Daughter’S Limited | Real estate | 2026 |
| S.M Building Team Ltd | Construction | 2016 |
| S.O.T.G Ltd | Manufacturing | 2021 |
| S19 Ltd | Professional & scientific | 2008 |
| S1A Consulting Ltd | Professional & scientific | 2010 |
| SA Prime Limited | Wholesale & retail | 2013 |
| Saad to Happy by X Ltd | Wholesale & retail | 2025 |
| SAC Trade Company Ltd | Other services | 2017 |
| Sadasothy Gold House Limited | Wholesale & retail | 2023 |
| Sadasothy Private Limited | Wholesale & retail | 2017 |
| Safari Cars Limited | Wholesale & retail | 1969 |
| Safeguarded Ltd | Public administration | 2010 |
| Safehaven Property Services Ltd | Hospitality | 2025 |
| Safi&Safi Property Investments Limited | Real estate | 2023 |
| Saful Express Limited | Transport & logistics | 2013 |
| Safz Heating & Plumbing Ltd | Construction | 2020 |
| Saga Builders Ltd | Construction | 2026 |
| Sahana Mitcham Limited | Other services | 2022 |
| SAI Education Ltd | Education | 2017 |
| SAI RAM Trading Ltd | Wholesale & retail | 2021 |
| Saima Developers Limited | Real estate | 2026 |
| Saimaz Limited | Wholesale & retail | 2023 |
| Sairam VS Investments UK Ltd | Real estate | 2025 |
| SAL Abubakar Car Repairs and Sprays Ltd | Administrative & support | 2016 |
| Sallymawufemo Limited | Health & social care | 2013 |
| Salo & Co. Ltd | Wholesale & retail | 2013 |
| Salomè Holistics Limited | Wholesale & retail | 2024 |
| Salsa GOT Soul: CIC | Education | 2026 |
| Salt & Paper Tooting Ltd | Hospitality | 2026 |
| SAM & HI Equestrian Limited | Manufacturing | 2013 |
| Sam&Co Property Management Limited | Real estate | 2026 |
| Samada Solutions Ltd | Professional & scientific | 2019 |
| Samasia Ltd | Wholesale & retail | 2020 |
| Sameer&Co Holdings Limited | Financial services | 2026 |
| SAMJ12 Limited | Real estate | 2024 |
| Sammi Sunshines Ltd | Arts & recreation | 2021 |
| Sammy Garden Ltd | Administrative & support | 2021 |
| Samuel Odede-Parker Limited | Health & social care | 2021 |
| Samz Accountancy Services Limited | Professional & scientific | 2020 |
| Samz Construction Services Ltd | Construction | 2021 |
| Samz Nutrition Services Limited | Health & social care | 2021 |
| Samz Property Services Ltd | Real estate | 2025 |
| SAN Foster Limited | Real estate | 2021 |
| SAN George Construction Ltd | Manufacturing | 2026 |
| Sanbooks Limited | Professional & scientific | 2026 |
| Sancta Familia Catholic Academy Trust | Education | 2023 |
| Sand and Crafts Ltd | Wholesale & retail | 2024 |