| Desrin Elixir Limited | Professional & scientific | 2022 |
| Dessert Island RUW Ltd | Hospitality | 2017 |
| Desserted & Co. Ltd | Hospitality | 2023 |
| Destination Milton Keynes Limited | Other services | 2006 |
| Destiny Healthcare Provider Limited | Health & social care | 2024 |
| Detac Limited | Information & communication | 2006 |
| Detailr Ltd | Administrative & support | 2014 |
| Detour Care Group Ltd | Health & social care | 2022 |
| Detour Properties Limited | Real estate | 1986 |
| Deut 316 Limited | Real estate | 2018 |
| Deutsch Tech Performance Limited | Wholesale & retail | 2016 |
| Deutsche Telekom Global Business Solutions UK Ltd. | Information & communication | 1978 |
| Deutschtech Ltd | Wholesale & retail | 2012 |
| DEV Sonic Limited | Information & communication | 2026 |
| Deva & Sons Ltd | Construction | 2023 |
| Deva Ductwork Limited | Construction | 2006 |
| Devanvi Ltd | Financial services | 2025 |
| Develop Life Ltd | Administrative & support | 2005 |
| Develop ME Ltd | Administrative & support | 2015 |
| Development Projects Ltd | Construction | 2024 |
| Developmk Ltd | Professional & scientific | 2020 |
| Devenish Estates (Lettings) Limited | Real estate | 2017 |
| Devenish Estates Limited | Real estate | 1997 |
| Devgun Production Ltd | Information & communication | 2019 |
| Devi Retail Limited | Wholesale & retail | 2024 |
| Devikav Ltd | Wholesale & retail | 2022 |
| Devine Feminine Ltd | Other services | 2025 |
| Devine Visitation Angels Limited | Health & social care | 2017 |
| Devish Tech Limited | Information & communication | 2019 |
| Devki Properties Limited | Real estate | 2025 |
| Devon & Cornwall Hampers Limited | Wholesale & retail | 2016 |
| Devon Composites Limited | Manufacturing | 2007 |
| Devonish Pantlin Limited | Information & communication | 2020 |
| Devonshire Architects Limited | Administrative & support | 2020 |
| Devonshire House Network Ltd | Administrative & support | 2013 |
| Devos Maintenance Ltd | Extraterritorial | 2017 |
| Devsource Limited | Information & communication | 2006 |
| Dewsco Holdings Ltd | Financial services | 2025 |
| Dexr Scan Ltd | Health & social care | 2026 |
| Dexsam Consulting Limited | Education | 2014 |
| DEY BBQ Burrito Ltd | Hospitality | 2024 |
| Dezel Estates Ltd | Real estate | 2020 |
| Dezola Ltd | Information & communication | 2022 |
| DFA Logistics Limited | Transport & logistics | 2022 |
| DFA UK & IRL Limited | Other services | 2017 |
| DFH MK Motors Ltd | Wholesale & retail | 2022 |
| DFL Transport One Ltd | Transport & logistics | 2015 |
| DG Construction Utilities Ltd | Construction | 2025 |
| DGA One Limited | Construction | 2016 |
| DGF Flooring Limited | Construction | 2022 |
| DGK Partners Ltd | Real estate | 2023 |
| DGM Properties Ltd | Real estate | 2021 |
| Dgspecialist Consulting Limited | Other services | 2026 |
| DGT Design Studio Ltd | Professional & scientific | 2024 |
| DGW Consultancy Ltd | Construction | 2012 |
| DH Construction and Sons Ltd | Construction | 2020 |
| Dhal Saas Solutions Limited | Information & communication | 2023 |
| Dhami M.D. Ltd | Health & social care | 2024 |
| DHD Investments Limited | Real estate | 2024 |
| DHD Logistic Solutions Limited | Administrative & support | 2025 |
| DHD Logistics Ltd | Transport & logistics | 2025 |
| DHD Temperature Controlled Transport Ltd | Transport & logistics | 2011 |
| Dhila Investments PTY Limited | Real estate | 2015 |
| Dhillon Logistics Services Ltd | Transport & logistics | 2024 |
| Dhindsa Build Ltd | Administrative & support | 2025 |
| DHL GBS (UK) Limited | Administrative & support | 1981 |
| DHL Real Estate (UK) Limited | Wholesale & retail | 1973 |
| DHL Services Limited | Administrative & support | 1997 |
| DHL Supply Chain International Limited | Transport & logistics | 1956 |
| DHL Supply Chain Limited | Transport & logistics | 1954 |
| Dhmg Limited | Information & communication | 2009 |
| Dhruvika Group Ltd | Transport & logistics | 2026 |
| DHS Packaging Services Limited | Administrative & support | 2024 |
| DHS Partners Ltd | Information & communication | 2008 |
| Dhylan Services Limited | Professional & scientific | 2016 |
| DI Napoli Limited | Hospitality | 2026 |
| DI ZHU QIU Ltd. | Wholesale & retail | 2025 |
| Diabexo Limited | Professional & scientific | 2025 |
| Dial a Delivery Ltd | Wholesale & retail | 2015 |
| Dialhouse HR Limited | Administrative & support | 2018 |
| Diallo Peli Cuisine Ltd | Hospitality | 2025 |
| Diamate Biotechnologies Limited | Financial services | 2015 |
| Diamate UK Ltd | Wholesale & retail | 2001 |
| Diamond 2000 Ltd | Other services | 2000 |
| Diamond Associate Limited | Administrative & support | 2020 |
| Diamond Cleaning Services (UK) Limited | Other services | 2003 |
| Diamond Club MK Ltd | Other services | 2025 |
| Diamond Court Management (MK) Limited | Real estate | 2006 |
| Diamond LUX Ltd | Health & social care | 2022 |
| Diamond Luxe Ltd | Real estate | 2026 |
| Diamond Meadow Properties Limited | Real estate | 2025 |
| Diamond MK Property Limited | Real estate | 2020 |
| Diamond Phoenix Automation Limited | Other services | 2012 |
| Diamond Properties (MK) Limited | Real estate | 2020 |
| Diamond Tax & Consulting Ltd | Professional & scientific | 2025 |
| Diamondrome Ltd | Administrative & support | 2025 |
| Diaspora Business Networks Limited | Professional & scientific | 2023 |
| Diaspora Freight Services Ltd | Transport & logistics | 2013 |
| Diaspora Global CIC | Information & communication | 2026 |
| Diatribe Consultants Limited | Information & communication | 2011 |