| Sadgiri Limited | Real estate | 2024 |
| Sadiya Academy Limited | Education | 2023 |
| Sadonext Limited | Information & communication | 2024 |
| Saesa Industries Limited | Administrative & support | 2025 |
| SAF Heritage UK Limited | Real estate | 2024 |
| Safa MK Ltd | Hospitality | 2025 |
| Safaah Health Care Limited | Health & social care | 2023 |
| Safari Enterprise MK Limited | Transport & logistics | 2022 |
| Safari Health Hub CIC | Arts & recreation | 2021 |
| Safari MK Ltd | Administrative & support | 2026 |
| Safari MMA Limited | Arts & recreation | 2018 |
| Safari Strike Ltd | Wholesale & retail | 2025 |
| Safari Technology Ltd | Information & communication | 2018 |
| Safe Agent Ltd | Information & communication | 2008 |
| Safe and Healthy Homes (Handyperson) Limited | Construction | 2014 |
| Safe and Healthy Homes Limited | Construction | 2017 |
| Safe AS Houses Locksmiths Limited | Manufacturing | 2021 |
| Safe Check Electrical Ltd | Construction | 2017 |
| Safe Civils Solutions Ltd | Construction | 2024 |
| Safe Hands Medical Ltd | Health & social care | 2014 |
| Safe Haven Community International CIC | Other services | 2024 |
| Safe Lane Trading Company Limited | Administrative & support | 2019 |
| Safe People Services Ltd | Professional & scientific | 2022 |
| Safe Soul Ltd | Professional & scientific | 2024 |
| Safeb Logistics Limited | Transport & logistics | 2017 |
| Safeguards Security Services Ltd | Administrative & support | 2013 |
| Safelet Property Solutions Ltd | Real estate | 2025 |
| Safem FM Ltd | Information & communication | 2021 |
| Safem Ltd | Hospitality | 2013 |
| Safenames Ltd | Information & communication | 1999 |
| Safenames Property Solutions Limited | Real estate | 2024 |
| Safeside Stands Ltd | Other services | 2024 |
| Safesmart Limited | Professional & scientific | 2002 |
| Safesmart SSP Ltd | Professional & scientific | 2024 |
| Safetire Ltd | Other services | 2024 |
| Safety and Learning Discovery Centre Limited | Education | 1998 |
| Safety Centre (Hazard Alley) Limited | Education | 1992 |
| Safety Eagles Limited | Professional & scientific | 2019 |
| Safety Genius Ltd | Professional & scientific | 2017 |
| Safety Inspections (UK) Limited | Professional & scientific | 2002 |
| Safety NET Healthcare Ltd | Public administration | 2022 |
| Safewater Solutions Limited | Water & waste | 2011 |
| Safeway Care Services Limited | Health & social care | 2024 |
| Safeway Enterprises Limited | Transport & logistics | 2019 |
| Saffire Estates Limited | Real estate | 2021 |
| Saffron Street Management Company Ltd | Households | 2007 |
| Saffronduskpublishing Ltd | Arts & recreation | 2024 |
| Safya Limited | Real estate | 2018 |
| Safya Prime Limited | Real estate | 2024 |
| SAG Livinghope Limited | Hospitality | 2022 |
| Saga Consultancy Limited | Health & social care | 2019 |
| Sage Concepts Limited | Wholesale & retail | 2024 |
| Sage Send Solutions Ltd | Education | 2026 |
| Sahaka Limited | Wholesale & retail | 2025 |
| Sahara Hunting UK Ltd | Wholesale & retail | 2023 |
| Sahara Open Ltd | Other services | 2026 |
| Sahishnu Sriman Ltd | Information & communication | 2015 |
| Sahnia Limited | Wholesale & retail | 2021 |
| Sahoon Services Ltd | Information & communication | 2013 |
| Sahtas UK Ltd | Manufacturing | 2010 |
| SAI 4S Limited | Hospitality | 2024 |
| SAI Alupack Ltd | Manufacturing | 2022 |
| SAI Aryan Commercial Properties Limited | Real estate | 2026 |
| SAI Aryan Holdings Ltd | Financial services | 2025 |
| SAI Aryan Properties Limited | Real estate | 2017 |
| SAI Aryan Properties One Limited | Real estate | 2019 |
| SAI Aryan Rentals Limited | Real estate | 2019 |
| SAI Aryan Supported Living CIC | Health & social care | 2026 |
| SAI Baba Properties Ltd | Real estate | 2022 |
| SAI Equities and Assets Limited | Financial services | 2026 |
| SAI Group Private Limited | Information & communication | 2016 |
| SAI Hasika Homes PVT Ltd | Real estate | 2017 |
| SAI JI Real Estates Limited | Real estate | 2025 |
| SAI Kotturu Technologies Ltd | Information & communication | 2017 |
| SAI Logistics Limited | Transport & logistics | 2007 |
| SAI Solutions Limited | Information & communication | 2013 |
| SAI Suhit PVT Ltd | Real estate | 2025 |
| SAI Training Limited | Information & communication | 2010 |
| SAI Virya Limited | Professional & scientific | 2018 |
| Saiarushi Limited | Health & social care | 2013 |
| Saicloud Ltd | Information & communication | 2020 |
| Saidhanya Solutions Limited | Information & communication | 2014 |
| Saidi Estates Ltd | Real estate | 2024 |
| Sail Properties Ltd | Real estate | 2019 |
| Sail Vale Limited | Information & communication | 2016 |
| Sailhouse Cars Limited | Wholesale & retail | 2017 |
| Saim Consulting Ltd | Professional & scientific | 2020 |
| Sainex Motor Group Ltd | Wholesale & retail | 2025 |
| Sainsburg Privated Limited | Health & social care | 2014 |
| Saintly Ltd | Extraterritorial | 2024 |
| Saintly Services Ltd | Extraterritorial | 2024 |
| Saints & Angels Healthcare Services Ltd | Health & social care | 2024 |
| Saints and Sinners Trust Limited(The) | Health & social care | 1961 |
| Saira Lawlor Coaching Ltd | Arts & recreation | 2022 |
| Sairaj UK Ltd | Information & communication | 2015 |
| Sairam Properties Investment Ltd | Real estate | 2024 |
| Saitnair Ventures Ltd | Wholesale & retail | 2025 |
| Sajak Limited | Wholesale & retail | 2020 |
| Sajan House Limited | Real estate | 2019 |
| Sajan Limited | Hospitality | 2005 |