| Secret Sessions Limited | Arts & recreation | 2014 |
| Secure 7 Security Ltd | Administrative & support | 2026 |
| Secured Tite Security Ltd | Administrative & support | 2024 |
| Selectors Group Limited | Information & communication | 2019 |
| Semple Investments Inc | Information & communication | 2015 |
| Sensory Playground Ltd | Wholesale & retail | 2020 |
| Serene Ascent Limited | Health & social care | 2026 |
| Serene Beauty Limited | Other services | 2005 |
| Serene Retail Limited | Other services | 2023 |
| Serenity Properties Suffolk Limited | Real estate | 2025 |
| Service Property Limited | Households | 2025 |
| Services Consortium Ltd | Construction | 2020 |
| Sete Margate Limited | Hospitality | 2022 |
| Setterfield Building Services Ltd | Construction | 2020 |
| Seven Fort Crescent Property Management Ltd | Real estate | 2024 |
| Sewell GAS Works Ltd | Construction | 2025 |
| SEX Brand Group Ltd | Wholesale & retail | 2025 |
| SFA Property Services Ltd | Construction | 2026 |
| Sgpropertybuyers Ltd | Real estate | 2025 |
| Shadowline Glazing Ltd | Manufacturing | 2019 |
| Shaja Fried Chicken Limited | Hospitality | 2026 |
| Shake That Social Ltd | Professional & scientific | 2022 |
| Shakespeare Electrical Services Ltd | Construction | 2016 |
| Shamu Fried Chicken Ltd | Hospitality | 2024 |
| Sharda Food Ltd | Hospitality | 2018 |
| Sharlyn Court Flat Management Limited | Households | 1990 |
| Shashe Ltd | Hospitality | 2019 |
| Shaun Thomas Financial Services Ltd | Financial services | 2022 |
| Shawgate Friend Ltd | Real estate | 2024 |
| Shed Load of Sounds Ltd | Information & communication | 2024 |
| Shelina Limited | Wholesale & retail | 2022 |
| Ship Your Stuff Ltd | Construction | 2017 |
| Shore Lets Limited | Real estate | 2016 |
| Shore Property Limited | Real estate | 2016 |
| Shore Studio Design Ltd | Professional & scientific | 2021 |
| Shoreline Music Ltd | Information & communication | 2017 |
| Short Term LET Fire Risk UK Ltd | Real estate | 2026 |
| Shri Hari Kent Limited | Real estate | 2023 |
| Siddiqi Solution Ltd | Wholesale & retail | 2025 |
| Sierra Estates Spain Limited | Real estate | 2023 |
| Sign and Safety Co Ltd | Public administration | 2026 |
| Simijen Services Ltd | Health & social care | 2023 |
| Simon Spurrier Ltd. | Arts & recreation | 2014 |
| Simtech Computer Systems Limited | Information & communication | 1998 |
| Sinclair Vehicles Limited | Manufacturing | 2023 |
| Sincopallo Ltd | Hospitality | 2019 |
| Singer & Singer Ltd | Information & communication | 2016 |
| Sirca Holdings Ltd | Real estate | 2026 |
| Siren Social Limited | Professional & scientific | 2025 |
| SIX Crown Investments Ltd. | Real estate | 2016 |
| Sixteen Muirkirk RTM Company Limited | Households | 2020 |
| SJC Construction Ltd | Construction | 2017 |
| SJC Windows & Doors Ltd | Construction | 2023 |
| SJG Home Improvements Limited | Other services | 2012 |
| SJG Music Ltd | Arts & recreation | 2024 |
| SJS Dream Spaces Ltd | Construction | 2022 |
| Sketchcube Ltd | Professional & scientific | 2019 |
| SKM Electrical Kent Ltd | Construction | 2019 |
| Skywise Aviation Limited | Arts & recreation | 2019 |
| Slab Fish Bar & Grill Limited | Hospitality | 2026 |
| Slabs Margate Limited | Hospitality | 2020 |
| Slat Limited | Real estate | 2013 |
| Sleek Electrical Services Ltd | Construction | 2026 |
| Sleepy Sound Ltd | Arts & recreation | 2024 |
| Sleepyteepeeuk Ltd | Information & communication | 2018 |
| Sleevenote Ltd | Arts & recreation | 2020 |
| Slice of the PIE Ltd | Financial services | 2026 |
| SLN Cleaning Ltd | Administrative & support | 2021 |
| Slosh Potz Ltd | Wholesale & retail | 2025 |
| Slow Down Limited | Professional & scientific | 2014 |
| Smarden Developments Limited | Construction | 2016 |
| Smart Client Ltd | Other services | 2022 |
| Smart Climate Ltd | Construction | 2026 |
| Smart Jointing Connections Ltd | Manufacturing | 2025 |
| Smart Precision Limited | Administrative & support | 2013 |
| Smart-In Jointing Services Ltd | Manufacturing | 2024 |
| Smartpitch Technologies Ltd | Information & communication | 2026 |
| Smith Classic & Performance Cars Ltd | Wholesale & retail | 2018 |
| Smith James Plumbing Ltd | Construction | 2021 |
| Smiths Court Hotel Limited | Hospitality | 2010 |
| Smiths Installations Limited | Construction | 2022 |
| Smugglers Agency Ltd | Arts & recreation | 2024 |
| SO Branding and Communications Limited | Professional & scientific | 2013 |
| SO Digital Communications Ltd | Administrative & support | 2016 |
| SOC Civils Ltd | Construction | 2024 |
| Social Enterprise Kent CIC | Education | 1985 |
| Socol Limited | Wholesale & retail | 2022 |
| Sofie Hemmet Limited | Other services | 2017 |
| Soft Drink Supplies Limited | Wholesale & retail | 2022 |
| Sohot Clean Limited | Administrative & support | 2021 |
| Sohot Laundry Limited | Administrative & support | 2021 |
| Sohot Luxe Ltd | Hospitality | 2024 |
| Sohot Stays Limited | Hospitality | 2021 |
| Solar Solutions Group Ltd | Other services | 2023 |
| Solarstreamuk Ltd | Construction | 2025 |
| Soliam.Biz Ltd | Information & communication | 2014 |
| Solicare (UK) Limited | Wholesale & retail | 2008 |
| Solidspace Solutions Ltd | Manufacturing | 2024 |
| Solstice Studio Ltd | Education | 2023 |
| Soma Spa Ltd | Wholesale & retail | 2025 |