| Stefan Nastase Ltd | Construction | 2024 |
| Stefan Thomas Developments Ltd | Manufacturing | 2019 |
| Stefday Leisure Ltd | Other services | 2019 |
| Stella Taps Limited | Extraterritorial | 2020 |
| Stendall Properties Ltd | Real estate | 2022 |
| Stephen Illingworth Architects Ltd | Construction | 2022 |
| Stephen Monk Limited | Information & communication | 2024 |
| Sterling Decorating Services Ltd | Construction | 2001 |
| Steve Hart Haulage Limited | Transport & logistics | 2002 |
| Steve's Pallets Ltd | Other services | 2018 |
| Stevenson Rentals Limited | Real estate | 2017 |
| Sthumytion Ltd | Transport & logistics | 2021 |
| Stichd UK Ltd | Wholesale & retail | 2005 |
| Stockwell House Investment Limited | Real estate | 2026 |
| Stokrotka ML Ltd | Wholesale & retail | 2025 |
| Stone Treasures Limited | Wholesale & retail | 2022 |
| Stonebridge Property Partners Ltd | Real estate | 2026 |
| Stonegate FM Ltd | Administrative & support | 2025 |
| Stoneley's Garage Services Ltd | Wholesale & retail | 2024 |
| Stones Mobile Tyre Specialist Ltd | Transport & logistics | 2026 |
| Stones Recovery Ltd | Transport & logistics | 2026 |
| Stoneworks Education Limited | Education | 2014 |
| Stop & Go Kirkby Ltd | Wholesale & retail | 2025 |
| Stopfords (Chesterfield) Limited | Extraterritorial | 2019 |
| Stopfords (Holdings) Limited | Extraterritorial | 2025 |
| Stopfords (Mansfield) Limited | Professional & scientific | 2001 |
| Storage Masters Limited | Transport & logistics | 2025 |
| Storm Tech International Limited | Wholesale & retail | 2016 |
| Storth Properties Ltd | Real estate | 2024 |
| Story Internet Limited | Information & communication | 2020 |
| STRADA31 Limited | Wholesale & retail | 2023 |
| Strafe Limited | Professional & scientific | 2013 |
| Strafe Ventures Ltd | Financial services | 2020 |
| Strategic Assistance Limited | Professional & scientific | 2013 |
| Strategic Property Limited | Real estate | 2015 |
| Street Lighting Solutions Ltd | Construction | 2025 |
| Strive Construction Training Solutions Ltd | Education | 2021 |
| Strix Business Solutions Limited | Professional & scientific | 2010 |
| Stronghold Legacy Planning Ltd | Financial services | 2022 |
| Strop CRM Ltd | Information & communication | 2023 |
| Structuri Design Ltd | Professional & scientific | 2021 |
| Stuart Richards Driving Limited | Education | 2017 |
| Stuart Sheppard Ltd | Construction | 2014 |
| Stuart Sidwell Conservatories Limited | Construction | 2001 |
| Studio 29 Hair & Beauty Ltd | Other services | 2015 |
| Studio 350 Limited | Professional & scientific | 2024 |
| SUB City Catering Limited | Hospitality | 2026 |
| Subpro Services Ltd | Administrative & support | 2024 |
| Successful Foods Ltd | Manufacturing | 2025 |
| Sudell Franchise Limited | Administrative & support | 2020 |
| SUE Firth Limited | Professional & scientific | 2008 |
| SUE Fish Bar 2 Ltd | Hospitality | 2026 |
| Suite Designs Furniture & Beds Limited | Wholesale & retail | 2015 |
| Suke Property Limited | Real estate | 2013 |
| Sukhnoor Holdings Limited | Households | 2020 |
| Sumal and Son's Haulage Limited | Wholesale & retail | 2019 |
| Sumal Stores Limited | Wholesale & retail | 2022 |
| Summercourt Wealth Management Limited | Administrative & support | 2019 |
| Summers Installations Limited | Construction | 2016 |
| Summit Gate Properties Limited | Real estate | 2025 |
| Summit Park Catering Ltd | Hospitality | 2019 |
| Summit Passive Fire Protection Limited | Construction | 2020 |
| Sun Inn Wheatley Limited | Extraterritorial | 2009 |
| Sunbeach Spas Limited | Wholesale & retail | 2023 |
| Sunflower Wellbeing Ltd | Education | 2021 |
| Sungis Ltd | Wholesale & retail | 2021 |
| Sunlight Analytics Ltd | Information & communication | 2024 |
| Sunner Limited | Hospitality | 2024 |
| Sunny Smiles Residential Care Ltd | Health & social care | 2025 |
| Sunnybees Property Ltd | Real estate | 2025 |
| Sunnydale Nursery Ltd | Education | 2015 |
| Sunraysia (UK) Limited | Administrative & support | 2005 |
| Sunrise Oxford Ltd | Other services | 2017 |
| Sunrixe Ltd | Health & social care | 2025 |
| Sunshine GAS Services Ltd | Construction | 2023 |
| Sunshine Hair & Body Ltd | Other services | 2012 |
| Sunus Property Ltd | Households | 2018 |
| Super Active Ltd | Wholesale & retail | 2019 |
| Super Asia Traders Ltd | Wholesale & retail | 2025 |
| Super E-Cig Ltd | Wholesale & retail | 2015 |
| Superdead Ltd | Professional & scientific | 2024 |
| Superdry Roofing Solutions Ltd | Construction | 2024 |
| Supermarket Milka Ltd | Wholesale & retail | 2023 |
| Supersnax 64582 Limited | Hospitality | 2015 |
| Supersnax Holdings Limited | Hospitality | 2024 |
| Supersnax Limited | Hospitality | 2012 |
| Supersnax Normanton Limited | Wholesale & retail | 2017 |
| Superstore 47 Ltd | Wholesale & retail | 2026 |
| Supertrick Z1 Limited | Wholesale & retail | 2003 |
| SUPPORTCARE24/7 Limited | Public administration | 2024 |
| Supra Communication Ltd | Administrative & support | 2022 |
| Supreme Education Ltd | Education | 2018 |
| Suptest Ltd | Information & communication | 2024 |
| Surgentsupplements Ltd | Health & social care | 2025 |
| Surplus Stock Xchange Limited | Wholesale & retail | 2026 |
| Surrender to IT Ltd | Information & communication | 2023 |
| Sustain Immigration Law Services Ltd | Professional & scientific | 2018 |
| Sustainable Agronomy Limited | Agriculture & fishing | 2001 |
| Sustainable Energy Connections Limited | Construction | 2010 |
| Sutton Convenience Ltd | Wholesale & retail | 2011 |