| Serya Ltd | Hospitality | 2019 |
| SES Security Limited | Information & communication | 2024 |
| Sesame Technology Limited | Information & communication | 2025 |
| SET UP 4U Ltd | Construction | 2022 |
| Setterfield Cladding Installation Limited | Construction | 2022 |
| Seven Hills Technology Ltd | Wholesale & retail | 2024 |
| Seven Hills Vision Marketing Consultancy Limited | Information & communication | 2013 |
| Severn Compliance Limited | Professional & scientific | 2019 |
| Sewell (Eco) Limited | Construction | 2023 |
| SF Electrical Services Limited | Professional & scientific | 2023 |
| SF Media Solutions Limited | Wholesale & retail | 2011 |
| SFD Enterprises Ltd | Hospitality | 2026 |
| Sgcc Property Ltd | Real estate | 2021 |
| Shabi Limited | Wholesale & retail | 2022 |
| Shacklocks LLP | | 2011 |
| Shacklocks Solicitors and Investment Advisors Limited | Real estate | 2011 |
| Shacklocks Solicitors Limited | Extraterritorial | 2011 |
| Shadow Smile Ltd | Wholesale & retail | 2023 |
| Shahidsobia Limited | Professional & scientific | 2019 |
| Shannon's Little Explorers Ltd | Health & social care | 2026 |
| Sharan Indian Curries Takeaway Ltd | Hospitality | 2025 |
| Shared Service Architecture Ltd | Professional & scientific | 2008 |
| Shark Training Limited | Administrative & support | 2015 |
| Sharmy Limited | Wholesale & retail | 2020 |
| Sharp HAT Trading Cards Limited | Wholesale & retail | 2025 |
| Shaun Curtis Limited | Wholesale & retail | 2010 |
| Shaw Distributing Ltd | Wholesale & retail | 2024 |
| Shaw Financial Services Ltd | Other services | 2018 |
| Shaw Sublimation Group Ltd | Wholesale & retail | 2024 |
| Shaws Global Contractors Limited | Professional & scientific | 2025 |
| Shaws Mechanical Services Ltd | Professional & scientific | 2025 |
| SHB Motions Ltd | Wholesale & retail | 2024 |
| Shear Advice Limited | Other services | 2013 |
| Shed Beds Limited | Manufacturing | 2021 |
| Sheds 4 U Ltd | Manufacturing | 2009 |
| Sheepbridge Estates Ltd | Real estate | 2026 |
| Sheerasbooze Limited | Wholesale & retail | 2017 |
| Shelby Company Nottingham Limited | Administrative & support | 2017 |
| Shelby's Scents Ltd | Manufacturing | 2020 |
| Shephards Retreat Newark Ltd | Real estate | 2025 |
| Sherwood Aluminium Systems Limited | Manufacturing | 1997 |
| Sherwood Binder & Box Ltd | Wholesale & retail | 2025 |
| Sherwood Bistro Ltd | Hospitality | 2025 |
| Sherwood Brickwork Ltd | Construction | 2017 |
| Sherwood Cabinets Ltd | Manufacturing | 2014 |
| Sherwood Care Homes Limited | Health & social care | 2000 |
| Sherwood Construction (East Midlands) Ltd | Professional & scientific | 2017 |
| Sherwood Construction Group Limited | Real estate | 2025 |
| Sherwood Consultancy Limited | Construction | 2018 |
| Sherwood Forest Lodge Limited | Hospitality | 2011 |
| Sherwood Grange Care Ltd | Real estate | 2020 |
| Sherwood Grange Management Limited | Households | 2003 |
| Sherwood Healing Ltd | Health & social care | 2021 |
| Sherwood Healthcare Limited | Health & social care | 2004 |
| Sherwood Home Improvements & Roofing Ltd | Construction | 2025 |
| Sherwood I.T. Consultantcy Limited | Information & communication | 2023 |
| Sherwood Oaks Gymnastics Academy | Arts & recreation | 2017 |
| Sherwood Oaks Leisure Limited | Wholesale & retail | 2013 |
| Sherwood Pines Camping Ltd | Hospitality | 2022 |
| Sherwood Portable Accommodation Limited | Hospitality | 2005 |
| Sherwood Regrind UK Ltd | Manufacturing | 2022 |
| Sherwood Sales Limited | Wholesale & retail | 2024 |
| Sherwood Skin Clinic Ltd | Other services | 2025 |
| Sherwood Training Limited | Professional & scientific | 2014 |
| Sherwood View Limited | Real estate | 2025 |
| Shetliffe Holdings Ltd | Financial services | 2024 |
| Shiloh Health & Homes Ltd | Households | 2025 |
| Shine Nails Spa Ltd | Other services | 2022 |
| Shire Concrete Ltd | Administrative & support | 2018 |
| Shire Fabrications Ltd | Manufacturing | 2019 |
| Shire Group Holdings Ltd. | Financial services | 2019 |
| Shirebrook Barber (F) Ltd | Other services | 2025 |
| Shirebrook Barber Ltd | Other services | 2024 |
| Shirebrook BBQ Ltd | Hospitality | 2024 |
| Shirebrook Business Services Limited | Professional & scientific | 2008 |
| Shirebrook Community Cricket Club CIC | Arts & recreation | 2022 |
| Shirebrook Developments Limited | Construction | 1993 |
| Shirebrook Miners' Welfare Social Club Limited | Hospitality | 1998 |
| Shirebrook Motor Factors Ltd | Wholesale & retail | 2026 |
| Shirebrook Properties Limited | Real estate | 2015 |
| Shirebrook Retail Limited | Wholesale & retail | 1996 |
| Shirebrook Services Limited | Administrative & support | 1981 |
| Shivam Enterprise Ltd | Wholesale & retail | 2018 |
| Shizuka Home Limited | Real estate | 2025 |
| Shoknan Properties Ltd | Real estate | 2024 |
| Shoknan Restaurant & Bar Ltd | Hospitality | 2023 |
| Shortiebullz 24HR Pet Response Limited | Agriculture & fishing | 2022 |
| Shtj Trading Limited | Wholesale & retail | 2021 |
| Shut the Front Door Properties Ltd | Real estate | 2018 |
| SI Home Property Ltd | Real estate | 2025 |
| SIA Care Group Limited | Health & social care | 2025 |
| Siam Boxing Ltd | Wholesale & retail | 2022 |
| Sibbs Ltd | Real estate | 2019 |
| Sibetei Ltd | Transport & logistics | 2018 |
| Sigma Circle UK Ltd | Wholesale & retail | 2023 |
| Sigmatau Design Ltd | Information & communication | 2025 |
| Signature Competition Hub Ltd | Wholesale & retail | 2026 |
| Signature Plates Ltd | Wholesale & retail | 2025 |
| Sihealth Ltd | Information & communication | 2014 |
| Sikwa Limited | Wholesale & retail | 2024 |