| Enii Ltd | Other services | 2024 |
| Enimpro Engineering for Improvement Limited | Professional & scientific | 2017 |
| Enjay NW LLP | | 2023 |
| ENK Services Limited | Professional & scientific | 2015 |
| Enki Infrastructure Ltd | Real estate | 2017 |
| Enkii Technologies Ltd | Professional & scientific | 2026 |
| Enkryptoxs Tech Limited | Information & communication | 2025 |
| Enku Ltd | Wholesale & retail | 2022 |
| Enlair Ltd | Manufacturing | 2021 |
| Enlightened Consulting Ltd | Wholesale & retail | 2024 |
| Enlightenment Care Services Ltd | Administrative & support | 2014 |
| Enliven Detailing Ltd | Wholesale & retail | 2025 |
| ENM Holdings Limited | Real estate | 2024 |
| Ennenga Consultant Limited | Professional & scientific | 2016 |
| Ennervale Developments Ltd | Real estate | 2009 |
| Ennisvale Limited | Real estate | 2017 |
| Ennoway Ltd | Wholesale & retail | 2023 |
| ENO DAN & Bless Foods Limited | Wholesale & retail | 2023 |
| Enol Services Ltd | Administrative & support | 2025 |
| Enoma Care Services Ltd | Health & social care | 2020 |
| Enova Business Ltd | Professional & scientific | 2025 |
| Enoviq Ltd | Wholesale & retail | 2024 |
| Enovy Ltd | Manufacturing | 2022 |
| Enoxtechnologiesuk Ltd | Information & communication | 2023 |
| Enoz X Ltd | Wholesale & retail | 2026 |
| Enpeco Limited | Professional & scientific | 1997 |
| Enplan Consultancy Services Limited | Health & social care | 2011 |
| ENREDA2 Limited | Administrative & support | 2021 |
| Enrich Aesthetics Ltd | Other services | 2022 |
| Enrich Aesthetics Training Ltd | Education | 2022 |
| Enrich Life Tech Ltd | Information & communication | 2018 |
| Enrich ME Limited | Education | 2013 |
| Enrich Medical Ltd | Health & social care | 2022 |
| Enright Limited | Professional & scientific | 2007 |
| Enroy Investment Ltd | Real estate | 2025 |
| Ensal Properties Limited | Real estate | 2017 |
| Ensco 1020 Limited | Professional & scientific | 2013 |
| Ensco 1096 Limited | Information & communication | 2014 |
| Ensco 1162 Limited | Real estate | 2015 |
| Ensco 1174 Limited | Real estate | 2016 |
| Ensco 1183 Limited | Financial services | 2016 |
| Ensco 1390 Limited | Financial services | 2020 |
| Ensco 1469 Limited | Financial services | 2022 |
| Ensco 1477 Limited | Financial services | 2023 |
| Ensco 1534 Limited | Financial services | 2025 |
| Ensco 1535 Limited | Financial services | 2025 |
| Ensco 1536 Limited | Financial services | 2025 |
| Ensco 1537 Limited | Financial services | 2025 |
| Ensco 1546 Limited | Financial services | 2025 |
| Ensco 1562 Limited | Information & communication | 2026 |
| Ensco 9547 Limited | Professional & scientific | 2020 |
| Ensco Finco LLP | | 2020 |
| Enseer Ltd | Information & communication | 2026 |
| Ensemble Technology Ltd | Information & communication | 2024 |
| Ensheng Limited | Hospitality | 2025 |
| Enshore Properties Limited | Real estate | 2023 |
| Enso Accountants Limited | Professional & scientific | 2018 |
| Enso Innovation Limited | Professional & scientific | 2021 |
| Enso Legal Limited | Professional & scientific | 2023 |
| Enso Leisure Trading Ltd | Hospitality | 2024 |
| Enspec Limited | Construction | 2020 |
| Enspection Limited | Professional & scientific | 2020 |
| ENT Consultant Services Limited | Health & social care | 2025 |
| ENT Medical Limited | Health & social care | 2023 |
| Entasko Limited | Information & communication | 2026 |
| Entellfibres Limited | Professional & scientific | 2008 |
| Enteractive Limited | Wholesale & retail | 2019 |
| Enterprise 25/8 Limited | Wholesale & retail | 2018 |
| Enterprise Financial Services (UK) Limited | Financial services | 2001 |
| Enterprise for Therapie and Coaching Ltd | Extraterritorial | 2025 |
| Enterprise Futures Limited | Real estate | 2018 |
| Enterprise Hardware Limited | Wholesale & retail | 2016 |
| Enterprise Information Technologies Limited | Information & communication | 2008 |
| Enterprise Networks Limited | Extraterritorial | 1997 |
| Enterprise One ERP Limited | Information & communication | 2025 |
| Enterprise Portfolio Management Ltd | Administrative & support | 2017 |
| Enterprise Q Ltd. | Manufacturing | 1996 |
| Enterprises & Investments Holding Limited | Wholesale & retail | 2026 |
| Enterprising Youth C.I.C. | Education | 2013 |
| Enterprize Cleaning Services Ltd | Administrative & support | 2011 |
| Enterprizer Technologies Limited | Professional & scientific | 1990 |
| Enterserve Ltd | Information & communication | 2006 |
| Entertainment First Ltd | Information & communication | 2024 |
| Enthalpy Limited | Administrative & support | 2009 |
| Entire Project Solutions Limited | Administrative & support | 2013 |
| Entire Project Solutions Properties Prestwich Limited | Construction | 2025 |
| Entity Streamz Ltd | Hospitality | 2024 |
| Entity Trading Company Ltd | Construction | 2025 |
| Entiyr Limited | Wholesale & retail | 2026 |
| Entmon Limited | Real estate | 2012 |
| Ento FM Limited | Other services | 2018 |
| Entopro Ltd | Manufacturing | 2023 |
| Entr Digital Ltd | Professional & scientific | 2023 |
| Entrance Matting Direct Limited | Construction | 2013 |
| Entred 9 Limited | Professional & scientific | 1936 |
| Entrenched Ltd | Real estate | 2025 |
| Entrepreneur Groundwork Guide Holding Company Limited | Financial services | 2022 |
| Entrepreneur Groundwork Guide Manchester Limited | Financial services | 2022 |
| Entrepreneurgroundworkguide Group UK Ltd | Administrative & support | 2008 |
| Entrepreneurs Unlocked CIC | Education | 2019 |