| Energy Leads Marketing Ltd | Administrative & support | 2024 |
| Energy Leverage Production Ltd | Information & communication | 2025 |
| Energy Performance Advice Ltd | Professional & scientific | 2023 |
| Energy Plan Savings Limited | Other services | 2020 |
| Energy Pricing and Metering Ltd | Professional & scientific | 2021 |
| Energy Reduction Management Ltd | Construction | 2010 |
| Energy Saver Installations Ltd | Construction | 2018 |
| Energy Saving Company (North West) Ltd | Administrative & support | 2024 |
| Energy Secure Ltd | Construction | 2015 |
| Energy Solutions ECO4 Ltd | Construction | 2024 |
| Energy Tech Friendly Limited | Construction | 2016 |
| Energy Therapy Ltd | Wholesale & retail | 2010 |
| Energy Utilities Ltd | Energy | 2020 |
| ENERGY2BUSINESSES Limited | Other services | 2013 |
| Energypro Connect Ltd | Financial services | 2023 |
| Energyzest Limited | Information & communication | 2011 |
| Enerst Care Ltd | Public administration | 2019 |
| Enervia Limited | Manufacturing | 2025 |
| Enerwell Clinic UK Ltd | Health & social care | 2024 |
| Enesky Facilities Management Ltd | Administrative & support | 2024 |
| Enesther Property Limited | Hospitality | 2024 |
| Enet Ltd | Wholesale & retail | 2025 |
| Enexify Ltd | Wholesale & retail | 2026 |
| Enfield MCR Limited | Wholesale & retail | 2025 |
| Enfold Trading Ltd | Wholesale & retail | 2026 |
| Enforce Ltd | Professional & scientific | 2025 |
| Enforcement Group Ltd | Public administration | 2023 |
| Enforcement Specialists Limited | Professional & scientific | 2016 |
| Enformed Solutions Limited | Information & communication | 2009 |
| Enfudo Consultancy Services Ltd | Information & communication | 2017 |
| ENG E Commerce Ltd | Wholesale & retail | 2025 |
| ENG Holdings Limited | Extraterritorial | 2001 |
| ENG Joinery Ltd | Construction | 2020 |
| Eng-Pm Limited | Other services | 2011 |
| Engage Case Management Ltd | Education | 2024 |
| Engage ESP Limited | Information & communication | 1999 |
| Engage Solutions Group Limited | Information & communication | 2017 |
| ENGAGE2STAGE CIC | Arts & recreation | 2020 |
| Engbox Engineering Services Ltd | Professional & scientific | 2019 |
| Engcon Limited | Professional & scientific | 2002 |
| Engel Johnson LLP | | 2009 |
| Engenis Limited | Real estate | 2006 |
| Engiglass Ltd | Manufacturing | 2024 |
| Engine FIX UK Ltd | Wholesale & retail | 2020 |
| Engine NO 4 Ltd | Arts & recreation | 2019 |
| Engine Pro Auto Service Ltd | Other services | 2021 |
| Engine Supplier Ltd | Wholesale & retail | 2024 |
| Engineer Sounds Ltd | Information & communication | 2015 |
| Engineer Team Network Limited | Construction | 2004 |
| Engineered Building Solutions Ltd | Construction | 2019 |
| Engineered Efficiency Limited | Professional & scientific | 2025 |
| Engineering and Architectural Services Limited | Other services | 2019 |
| Engineering and Motor Sport UK Limited | Professional & scientific | 2012 |
| Engineering Design & Models (Manchester) Limited | Manufacturing | 1994 |
| Engineering Global Services Ltd | Professional & scientific | 2022 |
| Engineering Ideas Ltd | Professional & scientific | 2006 |
| Engineering Services (Manchester) Ltd | Professional & scientific | 2023 |
| Engineering Tech Limited | Professional & scientific | 2017 |
| Enginerate Limited | Construction | 1997 |
| Enginerd Ltd | Professional & scientific | 2018 |
| ENGINES4DAYS Ltd | Wholesale & retail | 2025 |
| Enginuous Ltd | Information & communication | 2025 |
| Engiplus Ltd | Construction | 2020 |
| Engissol Ltd | Information & communication | 2017 |
| Engitech Limited | Wholesale & retail | 2017 |
| England Mexdel Social Limited | Public administration | 2026 |
| England Squash Foundation | Arts & recreation | 2010 |
| England Squash Limited | Arts & recreation | 1989 |
| English Cycling Union Limited | Arts & recreation | 1996 |
| English Lacrosse Association Limited | Arts & recreation | 1997 |
| English Language Channel Ltd | Education | 2012 |
| English-French Language Academy Ltd | Education | 2021 |
| Englisher Ltd | Education | 2022 |
| Engravegifts Limited | Information & communication | 2017 |
| Engraving Services Limited | Manufacturing | 1948 |
| Engtan Holdings Ltd | Construction | 2017 |
| Engturk Ltd | Wholesale & retail | 2023 |
| Enhance Aesthetics (MCR) Ltd | Health & social care | 2016 |
| Enhance Aesthetics at Peak Ltd | Health & social care | 2021 |
| Enhance Beauty Manchester Ltd | Other services | 2020 |
| Enhance IT Solutions Ltd | Information & communication | 2012 |
| Enhance Manchester Education Ltd | Education | 2023 |
| Enhance My Hair Ltd | Other services | 2021 |
| Enhance Performance Ltd | Arts & recreation | 2025 |
| Enhance Physique Ltd | Arts & recreation | 2024 |
| Enhance Property Renovations Ltd | Construction | 2025 |
| Enhance Social Care Ltd | Health & social care | 2021 |
| Enhance YOU Ltd | Wholesale & retail | 2018 |
| Enhanced Care and Support Services Ltd | Public administration | 2026 |
| Enhanced Didsbury Ltd | Real estate | 2016 |
| Enhancing Lives Community Care Ltd | Health & social care | 2021 |
| Enhet Limited | Wholesale & retail | 2026 |
| Enigma Cars Ltd | Wholesale & retail | 2020 |
| Enigma Corp Limited | Wholesale & retail | 2025 |
| Enigma Parfums Ltd | Wholesale & retail | 2024 |
| Enigma Promotions Limited | Wholesale & retail | 2025 |
| Enigma Rise Capital Ltd | Extraterritorial | 2026 |
| Enigma Venture Partners LLP | | 2024 |
| Enigma Ventures LLP | | 2025 |
| Enigmatic Solutions Limited | Extraterritorial | 2024 |