| Derma Transform Aesthetics Ltd | Other services | 2023 |
| Derma Transform Medical Services Limited | Health & social care | 2016 |
| Dermacist Ltd | Wholesale & retail | 2024 |
| Dermadent for Trading Ltd | Other services | 2021 |
| Dermaesthetica London Ltd | Health & social care | 2015 |
| Dermafix Limited | Other services | 2024 |
| Dermal Aesthetics Clinic Limited | Education | 2016 |
| Dermalogic Limited | Health & social care | 2016 |
| Dermawellness Ltd | Health & social care | 2024 |
| Dermdoc Limited | Professional & scientific | 2016 |
| Dermessence Ltd | Health & social care | 2024 |
| Dermexpert Limited | Health & social care | 2014 |
| Dermis Clinic Medical Aesthetics & Wellbeing Ltd | Health & social care | 2024 |
| Dermspectrum C.I.C. | Education | 2023 |
| Dermwise Ltd | Administrative & support | 2009 |
| Derry GP LLP | | 2019 |
| Derry Holdco Limited | Real estate | 2024 |
| Derry LP | | 2019 |
| Derry Nominees 1 Limited | Extraterritorial | 2018 |
| Derry Nominees 2 Limited | Extraterritorial | 2019 |
| Dertol Consults Limited | Professional & scientific | 2015 |
| Dervtech Limited | Manufacturing | 2015 |
| Derwent Connections Limited | Financial services | 2019 |
| Derwent Heights Management Company Limited | Households | 2004 |
| Derwent Southern (Holdings) Limited | Professional & scientific | 1989 |
| Derwent Trading Ltd | Wholesale & retail | 2025 |
| DES Fildes Limited | Arts & recreation | 1985 |
| DES in Pardes (Manchester) Ltd | Hospitality | 2025 |
| DES in Pardes Ltd | Wholesale & retail | 2021 |
| Desai Enterprise Limited | Wholesale & retail | 2015 |
| Desatascos LOW Cost Cantabria Limited | Construction | 2024 |
| Deseray Ltd. | Health & social care | 2022 |
| Desert Crown Contracting Company Ltd | Other services | 2021 |
| Desert Crown for Contracting Ltd | Wholesale & retail | 2022 |
| Desert Decor & Real Estate Limited | Real estate | 2025 |
| Desert Edge Company Ltd | Other services | 2025 |
| Desert Falcon Group Limited | Construction | 2026 |
| Desert Rose Boutique Ltd | Wholesale & retail | 2014 |
| Desertbox Limited | Hospitality | 2013 |
| Deserts Manchester Ltd | Hospitality | 2025 |
| Deserve IT Limited | Administrative & support | 2021 |
| Desh Properties Limited | Construction | 2018 |
| Deshen Investments Ltd | Real estate | 2018 |
| Deshi Bazar Ltd | Wholesale & retail | 2018 |
| Deshi Cuisine Ltd | Hospitality | 2024 |
| Deshio Attire Limited | Wholesale & retail | 2023 |
| Deshmi Traders Ltd | Wholesale & retail | 2019 |
| Desi Dough Ltd | Other services | 2025 |
| Desi Handi UK Limited | Hospitality | 2024 |
| Desi HUT Ltd | Hospitality | 2024 |
| Desi Khana Online Groceries Store Ltd | Wholesale & retail | 2020 |
| Desi Lounge UK Limited | Hospitality | 2008 |
| Desi Panjeeri Ltd | Wholesale & retail | 2025 |
| Desi Point Motor Repair Zone Ltd Ltd | Wholesale & retail | 2016 |
| Desi Sellers Ltd | Wholesale & retail | 2025 |
| Desi Spice Levenshulme Ltd | Hospitality | 2025 |
| Desi Starlight Collectives Ltd | Arts & recreation | 2024 |
| Desi Taste Private Limited | Hospitality | 2026 |
| Desidistrictentertainment Ltd | Arts & recreation | 2026 |
| Design & Build AI Ltd | Information & communication | 2025 |
| Design 2 Fit Ltd | Manufacturing | 2006 |
| Design 24 Consulting Limited | Professional & scientific | 2017 |
| Design a GIG Ltd | Other services | 2014 |
| Design Alive Holdings Ltd | Financial services | 2025 |
| Design Alive Limited | Education | 2011 |
| Design and Building Contractors Ltd | Construction | 2020 |
| Design and Building Roofing Ltd | Construction | 2025 |
| Design and Home Construction Limited | Construction | 2016 |
| Design Blueprint Ltd | Transport & logistics | 2020 |
| Design Build Dynamics Ltd | Construction | 2025 |
| Design by Emma Ltd | Professional & scientific | 2021 |
| Design by Helium Ltd | Professional & scientific | 2017 |
| Design Chops Limited | Other services | 2021 |
| Design Construct Ltd | Construction | 2025 |
| Design Element (UK) Limited | Wholesale & retail | 2003 |
| Design Essentials Limited | Wholesale & retail | 2011 |
| Design Focuz Ltd | Manufacturing | 2025 |
| Design for Good Club Ltd | Professional & scientific | 2023 |
| Design Help Limited | Real estate | 2022 |
| Design Hub Craft Ltd | Wholesale & retail | 2025 |
| Design in Mental Health Limited | Health & social care | 2010 |
| Design IT Studio Ltd | Information & communication | 2015 |
| Design Line Limited | Other services | 2022 |
| Design Manchester Ltd | Arts & recreation | 2015 |
| Design Manual Limited | Professional & scientific | 2015 |
| Design of the Times (2025) Ltd | Households | 2025 |
| Design of the Times Limited | Real estate | 2019 |
| Design Office Consultancy Limited | Professional & scientific | 2011 |
| Design Plan and Build Construction Ltd | Construction | 2026 |
| Design Quest Limited | Other services | 2024 |
| Design Services (NW) Limited | Professional & scientific | 1976 |
| Design Stars Ltd | Wholesale & retail | 2025 |
| Design to Install Ltd | Construction | 2021 |
| Design Wellness Ltd | Manufacturing | 2018 |
| Design X Build Ltd | Information & communication | 2025 |
| DESIGN2MEDIA Ltd | Professional & scientific | 2018 |
| Designease Limited | Manufacturing | 1993 |
| Designed by TEN Ltd | Professional & scientific | 2023 |
| Designely Ltd | Professional & scientific | 2026 |
| Designer Babies Ltd | Wholesale & retail | 2021 |