| Sahara Geophysical Limited | Mining & quarrying | 2013 |
| SAI Anusha Ltd | Hospitality | 2017 |
| SAI Prasanna Ltd | Hospitality | 2015 |
| Saint Solène Ltd | Wholesale & retail | 2026 |
| SAJ Investment Maidstone Ltd | Real estate | 2025 |
| Sajtos & SON Ltd | Transport & logistics | 2021 |
| SAK Consultancy Limited | Health & social care | 2015 |
| Saker's Financial Services Limited | Financial services | 2013 |
| Salaam Watandar Ltd | Education | 2025 |
| Sales Layer Ltd | Information & communication | 2021 |
| Saleskit AI Ltd | Extraterritorial | 2023 |
| Salesmaster Holdings Limited | Financial services | 2020 |
| Salesmaster UK Limited | Information & communication | 2008 |
| Salisbury Road (Farnborough) Management Limited | Households | 1994 |
| Sally Dernie Limited | Administrative & support | 2003 |
| Salmar Shipping and Transportation Limited | Transport & logistics | 1972 |
| Salmon Lane Limited | Administrative & support | 2004 |
| Salt Aquavit Limited | Hospitality | 2018 |
| Salters Law Ltd | Professional & scientific | 2016 |
| SAM Antonen Mental Performance Ltd | Arts & recreation | 2024 |
| SAM Milbery Limited | Wholesale & retail | 2005 |
| SAM Peacock Landscaping Limited | Administrative & support | 2021 |
| Sam's Socials Ltd | Professional & scientific | 2012 |
| Samabek Limited | Health & social care | 2015 |
| Samantha Hadley Case Management Ltd | Health & social care | 2023 |
| Samary Group Ltd | Wholesale & retail | 2026 |
| Samedan Ltd | Information & communication | 2001 |
| Samina&Safia Limited | Wholesale & retail | 2025 |
| Samis Properties Ltd | Real estate | 2026 |
| Samis Properties Ltd Ltd | Real estate | 2026 |
| Samme Allen Limited | Health & social care | 2016 |
| Samo&Gia Ltd | Transport & logistics | 2025 |
| Sampier Trading UK Ltd | Wholesale & retail | 2007 |
| Samprez Ltd | Wholesale & retail | 2023 |
| Samson Property Services (South East) Limited | Construction | 2015 |
| SAN Severo Limited | Hospitality | 2014 |
| Sanctify Holistic Health Limited | Health & social care | 2017 |
| Sandex Group Limited | Construction | 2017 |
| Sandgate Homes Ltd | Real estate | 2014 |
| Sandhar Ltd | Real estate | 2023 |
| Sandling Court (Maidstone) Management Company Limited | Administrative & support | 2005 |
| Sandling Road (Maidstone) Management Company Limited | Households | 2019 |
| Sandor's Exterior Cleaning Ltd | Administrative & support | 2025 |
| Sands Counselling and Psychotherapy Ltd | Extraterritorial | 2023 |
| Sandway Paving & Groundwork Limited | Construction | 2025 |
| Sandway Property Developments Limited | Construction | 2000 |
| Sangers (Maidstone) Limited | Wholesale & retail | 1979 |
| Sansun Company Limited | Real estate | 2026 |
| Santone Fire Safety and Compliance Limited | Public administration | 2025 |
| Sanzi Limited | Other services | 2020 |
| SAP Carpentry Ltd | Construction | 2020 |
| Saphion Limited | Information & communication | 2026 |
| Sapphire Park Management Company Limited | Households | 2021 |
| Sapphire Services (Kent) Limited | Administrative & support | 1996 |
| SAR Court Ltd | Real estate | 2018 |
| SAR Lodge Ltd | Real estate | 2018 |
| Sara Hairdressing & Beauty Ltd | Other services | 2021 |
| Sarah ANN Kennedy Limited | Information & communication | 2003 |
| Saralasathiyakumari Ltd | Health & social care | 2017 |
| Sargeant Services Ltd | Wholesale & retail | 2019 |
| Sargent’S Ltd | Transport & logistics | 2019 |
| Sarim Autos Limited | Wholesale & retail | 2010 |
| Sash Haven Ltd | Real estate | 2020 |
| Sasi Properties Ltd | Real estate | 2025 |
| Saturation Trust | Health & social care | 2008 |
| Savage Gym Ltd | Arts & recreation | 2022 |
| Saved Records & Events Ltd | Information & communication | 2009 |
| Savi Construction and Joinery Ltd | Construction | 2021 |
| Savina O'Neill Limited | Health & social care | 2015 |
| Saxon Mews (Maidstone) Residents' Company Limited | Households | 2015 |
| Saykov Ltd | Transport & logistics | 2019 |
| Saylon Private Limited | Administrative & support | 2014 |
| SB Projects South East Ltd | Construction | 2026 |
| Sbct Properties Ltd | Real estate | 2023 |
| Sbet Properties Limited | Real estate | 2022 |
| SBK Opulent Protection Ltd | Transport & logistics | 2020 |
| SBM83 Ltd | Construction | 2021 |
| Sbmv London Ltd | Wholesale & retail | 2016 |
| SBS 19 Engineering Ltd | Administrative & support | 2018 |
| SCA Tracker Ltd | Information & communication | 2026 |
| Scaldayt Ltd | Information & communication | 2017 |
| Scarpetta Limited | Hospitality | 2013 |
| Scarsas Electrical Limited | Construction | 2016 |
| Scent Envy Ltd | Wholesale & retail | 2025 |
| SCF Investments Limited | Real estate | 2015 |
| Schaefer Securities Limited | Real estate | 2026 |
| Scharge Ltd | Professional & scientific | 2020 |
| Schilling&Co Ltd | Wholesale & retail | 2020 |
| Schion Labs Ltd | Information & communication | 2026 |
| School Mews Hernhill Limited | Households | 2008 |
| School of Therapy Ltd | Education | 2025 |
| Schools Cheer Collective Ltd | Education | 2025 |
| Scientious Consulting Limited | Information & communication | 2023 |
| Sciolto Ltd | Wholesale & retail | 2024 |
| Scion Financial Ltd | Professional & scientific | 2020 |
| Scion Legal Ltd | Professional & scientific | 2021 |
| Scissor Handz Limited | Other services | 2015 |
| Scissor HANDZ2 Limited | Other services | 2016 |
| Scissor HANDZ3 Limited | Other services | 2019 |
| Scissor HANDZ4 Ltd | Other services | 2020 |