| SOL Bidco Limited | Financial services | 2024 |
| SOL Finco Limited | Financial services | 2024 |
| SOL Midco Limited | Financial services | 2024 |
| Solar Claims UK Ltd | Financial services | 2018 |
| Solar International Freight Limited | Extraterritorial | 1979 |
| Solarcrest (Macclesfield) Ltd | Extraterritorial | 2013 |
| Solarcrest Distribution Ltd | Construction | 2009 |
| Solarcrest Limited | Real estate | 1986 |
| Solcura Care Ltd | Administrative & support | 2025 |
| Sole Heat Limited | Wholesale & retail | 2014 |
| Solterre Partners Limited | Professional & scientific | 2026 |
| Solto Digital Ltd | Professional & scientific | 2022 |
| Soluen Limited | Construction | 2020 |
| Solutions (Work Wear & Corporate Clothing) Limited | Wholesale & retail | 2003 |
| Solutions Work Wear Direct Limited | Extraterritorial | 2015 |
| Solway Investment Property Limited | Real estate | 2024 |
| Something Digital Technologies Ltd. | Information & communication | 2016 |
| Sonia Allam Casting Limited | Arts & recreation | 2019 |
| Sonic Marketing Group Limited | Wholesale & retail | 2026 |
| Sonny Properties Ltd | Real estate | 2013 |
| Sonny TAT Limited | Financial services | 2025 |
| Sonny-Hub Ltd | Other services | 2024 |
| Sonuclar Ltd | Professional & scientific | 2025 |
| Sophia Ames Art Ltd | Arts & recreation | 2025 |
| Soros Limited | Professional & scientific | 2003 |
| Sort N Store 4 U Limited | Administrative & support | 2026 |
| Sound of Islay Ltd | Administrative & support | 2020 |
| Sounds Like Mike Limited | Manufacturing | 2020 |
| Source 7 Ltd | Other services | 2006 |
| South Coast & Nigel J Sellick Independent Funeral Directors Ltd | Other services | 2019 |
| Southern Environmental Solutions Limited | Professional & scientific | 2007 |
| Southgate Mews Limited | Households | 1972 |
| Southpark Developments Limited | Construction | 2003 |
| Southpark Properties (Macclesfield) Limited | Real estate | 2010 |
| Southside (Chorlton) Management Company Limited | Households | 2001 |
| Sowcar Farm Ltd | Agriculture & fishing | 2024 |
| SP & Co (UK) Ltd. | Wholesale & retail | 2011 |
| Space Art Interiors Design Ltd | Construction | 2018 |
| Space Counselling Limited | Other services | 2015 |
| Space Innovation Limited | Manufacturing | 2005 |
| Sparked Into Life Ltd | Administrative & support | 2018 |
| Sparkle Cleaning Macclesfield Limited | Households | 2015 |
| Sparkling Clean (Berkshire) Limited | Administrative & support | 2000 |
| Spearings Limited | Wholesale & retail | 2017 |
| Specialist Deals Ltd | Financial services | 2019 |
| Specialist Finishes London Ltd | Construction | 2024 |
| Specialist Freight Services Ltd | Transport & logistics | 2022 |
| Specialist Parts Solutions Ltd | Manufacturing | 2014 |
| Speed Start Limited | Extraterritorial | 2025 |
| Speedy Nikolov Ltd | Transport & logistics | 2025 |
| Speedy Peppers Limited | Hospitality | 2014 |
| Spencer Engineering Ltd | Professional & scientific | 2023 |
| Spencer-Speak Ltd | Financial services | 2025 |
| SPF Investments Limited | Real estate | 2025 |
| SPF QS Limited | Professional & scientific | 2015 |
| SPH Security & Maintenance Limited | Administrative & support | 2017 |
| Spheredigital Ltd | Manufacturing | 2026 |
| Sphinxs Security Ltd | Administrative & support | 2024 |
| Spicer Coaching & Training Ltd | Education | 2025 |
| Spinleg Ltd | Professional & scientific | 2020 |
| Spinnaker Corporate Finance Limited | Professional & scientific | 2012 |
| Spitfire Doors Limited | Manufacturing | 2015 |
| Splace.World Ltd | Information & communication | 2014 |
| Sport Positive Ltd | Administrative & support | 2018 |
| Sports Branding Limited | Professional & scientific | 2013 |
| Sprayway 2010 Limited | Wholesale & retail | 2004 |
| Sprayway Limited | Extraterritorial | 1972 |
| Spring Farm Holdings Unlimited Company | Agriculture & fishing | 2016 |
| Spring Part Manufacturing Limited | Manufacturing | 1974 |
| Springfield Farm Estates Limited | Agriculture & fishing | 2024 |
| Springfield Nurseries Limited | Agriculture & fishing | 2022 |
| Sproston Property Holdings Limited | Real estate | 2025 |
| SQ2 Projects Ltd | Construction | 2022 |
| Sqeptech Ltd | Information & communication | 2018 |
| Square Green Limited | Real estate | 2022 |
| Square Safety Solutions Limited | Professional & scientific | 2025 |
| Squirrel Communications Limited | Information & communication | 2007 |
| SRI Nihira UK Ltd | Wholesale & retail | 2024 |
| Sril Technologies Limited | Information & communication | 2014 |
| SRT Product Consulting Ltd | Professional & scientific | 2023 |
| SS & Furniture Ltd | Real estate | 2022 |
| Sscp Blink Bidco Limited | Wholesale & retail | 2015 |
| ST Andrews Place Management Company 1 Limited | Real estate | 2014 |
| ST Andrews Place Management Company 3 Limited | Real estate | 2014 |
| ST Annes Development Ltd | Construction | 2024 |
| ST Clement Court (Urmston) RTM Company Limited | Households | 2020 |
| ST Joseph Limited | Hospitality | 2002 |
| ST Luke's Care Home Ltd | Health & social care | 2026 |
| ST Michael's Park Estate Management Company Limited | Real estate | 2021 |
| St.George Import & Export Limited | Hospitality | 2016 |
| St.Peter's House Management Company Limited | Households | 1988 |
| Stableyard Catering Ltd | Hospitality | 2018 |
| Stag Housing and Property Development Limited | Construction | 2018 |
| Stallion Cars Limited | Wholesale & retail | 2018 |
| Stamford Capital Limited | Financial services | 2015 |
| Stanfrank Bond Limited | Construction | 2021 |
| Stanier Farms Limited | Agriculture & fishing | 2025 |
| Stanier Services Limited | Other services | 2011 |
| Stanley Gate Holdings Ltd | Financial services | 2026 |
| Stanley Press Equipment Limited | Manufacturing | 2004 |