| Roland Moss Limited | Wholesale & retail | 1946 |
| Roller Discos Ltd | Arts & recreation | 2022 |
| Rollers Corporate Ltd | Arts & recreation | 2023 |
| Rollinson Building and Maintenance Ltd | Construction | 2014 |
| Rollinson Plumbing & Heating Ltd | Construction | 2015 |
| Rolph & Co Photography Ltd. | Professional & scientific | 2017 |
| Romano Security Consulting Limited | Information & communication | 2019 |
| Romek Music Limited | Information & communication | 2008 |
| Ronan Construction Ltd | Construction | 2026 |
| Ronan Consulting Ltd | Construction | 2023 |
| Ronan FOX Ltd | Real estate | 2025 |
| Roob Investments Limited | Real estate | 2025 |
| Roofing AMB Ltd | Construction | 2023 |
| Roofman Nationwide Limited | Administrative & support | 2016 |
| Rookery (2004) Management Company Limited | Real estate | 2003 |
| Roomi Faris Limited | Real estate | 2026 |
| Roost (North West) Ltd | Hospitality | 2020 |
| Roost (Stockport) Ltd | Hospitality | 2020 |
| Ropar Ltd | Construction | 2025 |
| Rosanero Restaurant Ltd | Hospitality | 2010 |
| Rosegarth House Limited | Real estate | 2021 |
| Rosegarth Management Limited | Households | 2022 |
| Rosehill Furnishings Group Limited | Manufacturing | 2023 |
| Rosey Dog Walks Ltd | Other services | 2026 |
| Rosico Limited | Administrative & support | 2010 |
| Rosso Associates Limited | Information & communication | 2006 |
| Rosyth Property Management (UK) Limited | Financial services | 2019 |
| Rough HEY Management Limited | Real estate | 2015 |
| ROW Services Ltd | Construction | 2021 |
| Rowdie Clothing Ltd | Wholesale & retail | 2025 |
| ROY Mccarthy Coaches Limited | Transport & logistics | 2010 |
| Royle Windows, Doors and Conservatories Ltd | Construction | 2015 |
| Royston Sport Horses Equestrian Centre Ltd | Agriculture & fishing | 2023 |
| Royston Waller Ltd | Wholesale & retail | 2017 |
| Rprunty Limited | Hospitality | 2020 |
| RRI Consulting Ltd | Information & communication | 2014 |
| Rtab Logistics Ltd | Transport & logistics | 2026 |
| RTP Independent Financial Advice Limited | Financial services | 2012 |
| RTR Commercial Ltd | Real estate | 2023 |
| RTR Installations Ltd | Construction | 2025 |
| Rtribe Ltd | Information & communication | 2017 |
| Rubena Solar Limited | Construction | 2011 |
| Rubicon Estates Limited | Construction | 2021 |
| Rubicon Homes (Fairoak) Limited | Construction | 2021 |
| Rubicon Homes (Gorsey) Limited | Construction | 2023 |
| Rubicon Homes (Hilltop) Limited | Construction | 2021 |
| Ruby Hotel Collection Holdings Limited | Real estate | 2019 |
| Ruckfunning Limited | Arts & recreation | 2024 |
| Rudyard Management Company Limited | Households | 1994 |
| Rugby House (Macclesfield) Maintenance Limited | Households | 1973 |
| Run Walk Draw Ltd | Arts & recreation | 2023 |
| Rural Resources Limited | Agriculture & fishing | 2011 |
| Rushmere GSL & Associates Ltd | Transport & logistics | 2018 |
| Rushton Spencer Limited | Professional & scientific | 1994 |
| Rushton Spencer Trustee Limited | Professional & scientific | 2025 |
| Russell Cardiology Limited | Health & social care | 2015 |
| Russell Clements Group Ltd | Real estate | 2017 |
| Russell Clements Property Investments Ltd | Real estate | 2018 |
| Russell Clements Property Solutions Limited | Real estate | 2014 |
| Russell Ward Property Maintenance Ltd | Construction | 2023 |
| Rutkowski Consulting Limited | Health & social care | 2022 |
| Rutter Enterprise Limited | Wholesale & retail | 2017 |
| Ruud Property Limited | Real estate | 2021 |
| RWP Digital Ltd | Information & communication | 2025 |
| Rylemount Green Ltd | Professional & scientific | 2014 |
| Rythmroom Limited | Information & communication | 2025 |
| S a Laughton Limited | Professional & scientific | 2014 |
| S and J Lyons Limited | Extraterritorial | 2013 |
| S Brown Engineering (Stockport) Limited | Manufacturing | 2005 |
| S C Consulting Ltd | Professional & scientific | 2026 |
| S K Contracting Limited | Agriculture & fishing | 2003 |
| S K F Electrical Ltd | Construction | 2007 |
| S M Horner Limited | Health & social care | 2010 |
| S R Workman Associates Ltd | Real estate | 2020 |
| S Roberts Electrical Contractors Limited | Construction | 2007 |
| S Rothwell Consultancy Limited | Professional & scientific | 2024 |
| S&A Brothers Investments Ltd | Real estate | 2025 |
| S&C Kershaw Limited | Real estate | 2020 |
| S&J Automotive Ltd | Wholesale & retail | 2017 |
| S. James Engineering Ltd | Professional & scientific | 2025 |
| S.D. Cowley Limited | Energy | 2003 |
| S.O.S. Heating Limited | Other services | 1993 |
| S.O.S. Plumbing Limited | Construction | 1992 |
| S.R. Ogden Ltd | Construction | 2010 |
| S2 Medical Communications Ltd | Professional & scientific | 2026 |
| S8R Ltd | Mining & quarrying | 2026 |
| SAA Commercial Services Limited | Professional & scientific | 2023 |
| Saara Medical Ltd | Professional & scientific | 2012 |
| Saas Hunters Ltd | Administrative & support | 2024 |
| Saba Energy Consulting Ltd | Professional & scientific | 2012 |
| Sabeel Limited | Health & social care | 2022 |
| Sabiha Studios Ltd | Information & communication | 2025 |
| Safe Engineering Solutions Ltd | Public administration | 2009 |
| Safety 2 Business Limited | Professional & scientific | 2007 |
| SAFETY2BUSINESS (South) Limited | Professional & scientific | 2026 |
| Safeway Rail Limited | Professional & scientific | 2025 |
| Safewire Limited | Information & communication | 2003 |
| Saffron Mall Limited | Wholesale & retail | 2025 |
| Sailing Along Limited | Education | 2010 |
| Sale Indian Cultural Society | Health & social care | 2013 |