| CWS (NW) Ltd | Construction | 2023 |
| Cyanelix Ltd | Information & communication | 2016 |
| Cygen Ltd | Information & communication | 2017 |
| Cypress Mews Ltd | Real estate | 2017 |
| D & B COX (Holdings) Ltd | Administrative & support | 2017 |
| D & F Contracting Ltd | Administrative & support | 2016 |
| D a Logistics Management Services Ltd | Wholesale & retail | 2025 |
| D and H Farming Limited | Agriculture & fishing | 2017 |
| D C Landscapes Lytham Ltd | Administrative & support | 2018 |
| D C T Metrology Limited | Manufacturing | 2018 |
| D H S M Properties Limited | Real estate | 2023 |
| D Serghi Holdings Ltd | Financial services | 2024 |
| D&P Prestige Lettings Ltd | Real estate | 2025 |
| D.C.Travis Limited | Construction | 1959 |
| D.M. Wilson T/A Wilson's Transport Contractors Ltd | Transport & logistics | 2019 |
| D.R.I.P Collection Ltd | Wholesale & retail | 2025 |
| D2 Advisory Ltd | Other services | 2025 |
| DAB Test Management Ltd | Other services | 2023 |
| Dabmsb Ltd | Extraterritorial | 2009 |
| Dakota Estates Limited | Real estate | 1993 |
| Dale Hammond Wealth Management Limited | Professional & scientific | 2014 |
| DAN Giles Carpentry Ltd | Construction | 2016 |
| Danbro Employment Umbrella Ltd | Administrative & support | 2017 |
| Danbro Financial Planning Limited | Financial services | 2017 |
| Danbro Trading Group Ltd | Financial services | 2015 |
| Danbro Workforce Solutions Ltd | Administrative & support | 2017 |
| Danny Rowe Football Coaching Ltd | Arts & recreation | 2024 |
| Dantia Media Limited | Information & communication | 2024 |
| Dapper Flooring Limited | Construction | 2018 |
| Darrt Consultancy Limited | Professional & scientific | 2025 |
| DAS Gruselkabinett Grip Services Ltd | Information & communication | 2022 |
| Dassc Ltd | Education | 2025 |
| Dataphrame Ltd | Information & communication | 2013 |
| Dave Holland Associates Ltd | Professional & scientific | 2026 |
| David Hawitt Limited | Professional & scientific | 2012 |
| David Stockton Ltd | Wholesale & retail | 2015 |
| Day of Sunshine (UK) Ltd | Other services | 2012 |
| DB SSC Limited | Education | 2022 |
| DBC Land and Building Ltd | Administrative & support | 2018 |
| DBH Electrical Ltd | Energy | 2021 |
| Dccper Holdings Limited | Information & communication | 2015 |
| Ddks Legacy Systems Limited | Information & communication | 2018 |
| Dearden Ecology Ltd | Professional & scientific | 2026 |
| Declan Brookes Ltd | Wholesale & retail | 2018 |
| Deignan Advisory Limited | Professional & scientific | 2025 |
| Della Holliday Ltd | Health & social care | 2015 |
| Delve & SON Ltd | Real estate | 2024 |
| Dent Experts Limited | Wholesale & retail | 2001 |
| Derbe Developments Limited | Real estate | 2014 |
| Derby Arms Developments Ltd | Construction | 2021 |
| Derby Hill Investments Limited | Real estate | 2014 |
| Derby IT Ltd | Education | 2023 |
| Dermaluxe Advanced Aesthetics Ltd | Health & social care | 2025 |
| Design LAB Studios Ltd | Arts & recreation | 2022 |
| Designer Drapes (Fylde) Limited | Manufacturing | 2005 |
| Designwithdom Ltd | Professional & scientific | 2021 |
| Destinations Coaching Limited | Administrative & support | 2022 |
| DEV Engine Ltd | Information & communication | 2017 |
| Deva Victrix Ltd | Hospitality | 2023 |
| Devally Ltd | Extraterritorial | 2011 |
| Device Innovations Limited | Professional & scientific | 2015 |
| Devine Design Limited | Professional & scientific | 2012 |
| Dexcroft Limited | Real estate | 2016 |
| Dexter 21 Properties Ltd | Real estate | 2020 |
| Dexter Folks Ltd | Hospitality | 2023 |
| DF and JF Rentals Ltd | Real estate | 2023 |
| DH 24 Hour Ltd | Construction | 2024 |
| DH Auto & Electrical Limited | Construction | 2026 |
| DH Aviation Ltd | Other services | 2022 |
| Diamondz Events Ltd | Hospitality | 2025 |
| Diane Rostron Limited | Professional & scientific | 2015 |
| Digital Eagles Studio Ltd | Information & communication | 2025 |
| Dimensions Fixed Seating Limited | Construction | 2017 |
| DINE2GETHER Limited | Hospitality | 2024 |
| Direct Displays & Exhibitions Limited | Administrative & support | 2002 |
| Direct NW Ltd | Wholesale & retail | 2023 |
| Disc Imports Limited | Information & communication | 1965 |
| Discovery Legal Services Limited | Administrative & support | 2019 |
| Discovery Partners Group Ltd | Professional & scientific | 2026 |
| Discoverypartners LLP | | 2019 |
| Disruptive Events Ltd | Professional & scientific | 2024 |
| Distance Accountant Ltd | Professional & scientific | 2020 |
| Ditchfield Glass Limited | Extraterritorial | 2003 |
| Divino Lytham Ltd | Hospitality | 2022 |
| Dixon Grange Ltd | Real estate | 2022 |
| DJT Global Investigations Ltd | Administrative & support | 2018 |
| DLE Project Management Ltd | Professional & scientific | 2025 |
| Dmb.It Consultancy Limited | Professional & scientific | 2011 |
| DMD Business Consultants Ltd | Other services | 2025 |
| DMW Project Management Limited | Information & communication | 2006 |
| Dog World Boarding Limited | Agriculture & fishing | 2024 |
| Doggie Coats Ltd | Manufacturing | 2014 |
| Doggy Day Care Kent Limited | Other services | 2016 |
| Dogma VIP Ltd | Wholesale & retail | 2022 |
| Donson Developments Ltd | Real estate | 2025 |
| Donson Holdings Ltd | Professional & scientific | 2025 |
| Donson Management Services Ltd | Professional & scientific | 2019 |
| Dottvet Ltd | Professional & scientific | 2024 |
| Doveycare Limited | Health & social care | 2025 |
| Downes 105 Ltd | Health & social care | 2019 |